Phytochemical Profile and Biological Activities of Extracts Obtained from Young Shoots of Blackcurrant (Ribes nigrum L.), European Blueberry (Vaccinium myrtillus L.), and Mountain Cranberry (Vaccinium vitis-idaea L.)

Horticulturae, Год журнала: 2023, Номер 9(11), С. 1163 - 1163

Опубликована: Окт. 24, 2023

This study explores the bioactive potential of young shoots from blackcurrant, European blueberry, and mountain cranberry, widely employed in gemmotherapy phytotherapy, as rich sources antioxidants, antimicrobial agents, anti-inflammatory components. The primary aims this were to enhance extraction conditions for compounds blackcurrant using Modde software experimental design, conduct a comprehensive phytochemical analysis cranberry shoot extracts through LC–MS analysis, evaluate vitro biological activities these optimized extracts. design comprised multiple variables: techniques, solvent type, time, apparent pH, solvent-to-vegetal product ratio. responses included total phenolic content, flavonoid condensed tannin antioxidant activity determined DPPH assay. Furthermore, was validated cell culture experiments, addition cytotoxicity assessments conducted on both normal cancer lines. Extracts obtained Ultra-Turrax 70% acetone displayed high levels polyphenolic enhanced potential, regardless origin. revealed predominant occurrence chlorogenic acid, hyperoside, isoquercitrin all examined samples. also significant when evaluated These results provide valuable insights into potent components present extracts, paving way further exploration therapeutic applications.

Язык: Английский

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UPLC-ESI-QTRAP-MS/MS Analysis to Quantify Bioactive Compounds in Fennel (Foeniculum vulgare Mill.) Waste with Potential Anti-Inflammatory Activity

Metabolites, Год журнала: 2022, Номер 12(8), С. 701 - 701

Опубликована: Июль 27, 2022

Foeniculum vulgare is a perennial aromatic plant whose cultivation produces large amounts of waste rich in bioactive compounds with promising anti-inflammatory activities. Nine selected metabolites were quantified through Ultra Performance Liquid Chromatography (UPLC) hyphenated to QTRAP mass spectrometry by using MRM (multiple reaction monitoring) was performed on four parts fennel: bulb, stem, little and leaf. Analysis revealed significant differences the amount metabolites, suggesting that stem leaf are most valuable waste. Phenolic acids glycosylated flavonoids for their known possible activities; fact, due this reason ability inhibit COX-1 COX-2 isoforms evaluated fluorometric assay, resulting specific inhibitors at certain concentrations. In conclusion, as fennel may be beneficial human health, clinical studies should include it nutraceuticals or functional foods consumption.

Язык: Английский

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An In Vitro and In Vivo Assessment of Antitumor Activity of Extracts Derived from Three Well-Known Plant Species

Plants, Год журнала: 2023, Номер 12(9), С. 1840 - 1840

Опубликована: Апрель 29, 2023

One of the objectives this study consists assessment antitumor activity several extracts from three selected plant species: Xanthium spinosum L., Trifolium pratense and Coffea arabica L. also a comparative biological activity, with aim establishing superior herbal extract for benefits. The phytochemical profile was established by HPLC-MS analysis. Further, were screened in vitro their antioxidant potential on two cancer cell lines: A549—human lung adenocarcinoma T47D-KBluc—human breast carcinoma normal cells. per vivo an Ehrlich ascites mouse model. presented high content compounds such as caffeoylquinic acids case X. (7.22 µg/mL—xanthatin, 4.611 µg/mL—4-O-caffeoylquinic acid) green coffee beans (10.008 µg/mL—cafestol, 265.507 acid), well isoflavones T. (6806.60 ng/mL—ononin, 102.78 µg/mL—biochanin A). Concerning results, strongest anticancerous effects. In vivo, viability decreased after bean administration, whereas oxidative stress reduction important tumor samples Cell administration cyclophosphamide associated extracts, respectively. These results suggested that or combination chemotherapy can induce lipid peroxidation cells decrease especially, extract.

Язык: Английский

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Role of the Green Husks of Persian Walnut (Juglans regia L.)—A Review

Horticulturae, Год журнала: 2023, Номер 9(7), С. 782 - 782

Опубликована: Июль 9, 2023

Green husks are the outer layer of walnut fruits. They form part agro-residues discarded away upon nut maturity in industry. Although it is not used, research studies show that green husk a rich source natural bioactive phytochemicals. A total 83 individual phenolic compounds were identified husks, mainly consisting naphthoquinones, flavonols, and hydroxycinnamic acids. There no standard profile walnuts; quantity quality vary by cultivar. Walnut extracts exhibit strong antioxidant activities play an important role plant’s defence mechanisms against diseases, attacking different plant organs. The study provides review content cultivars as documented studies. It also explores application various industries such traditional medicine, textile, wood, leather, beverage, agriculture. In addition, effects on biotic abiotic factors evaluated.

Язык: Английский

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Exploring the Ecological Implications, Gastronomic Applications, and Nutritional and Therapeutic Potential of Juglans regia L. (Green Walnut): A Comprehensive Review

Nutrients, Год журнала: 2024, Номер 16(8), С. 1183 - 1183

Опубликована: Апрель 16, 2024

The green walnut, which is frequently overlooked in favor of its more mature sibling, becoming a topic great significance because unique ecological role, culinary flexibility, and therapeutic richness. investigation the bioactive substances found walnuts their possible effects on human health has potential. Juglans regia L. an important component that affects soil health, biodiversity, overall dynamic habitats. Comprehending recording these consequences are essential for environmental management sustainable land-use strategies. Regarding cuisine, while black main attraction, have distinct tastes textures used variety dishes. Culinary innovation preservation cultural food heritage depend understanding exploration gastronomic characteristics. Omega-3 fatty acids, antioxidants, vitamins, minerals abundant walnuts, comprehensive nutritional profile. Walnuts possess wide range pharmacological properties, including antioxidant, antibacterial, antiviral, anticancer, anti-inflammatory, cognitive-function-enhancing properties. Consuming as part one's diet helps with antioxidant defense, cardiovascular general well-being. L., distinctive flavor texture combination, not only delicious but also supports nutrition practices. This review explores properties can be further studies various pharmaceutical applications.

Язык: Английский

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