Molecules,
Год журнала:
2024,
Номер
29(9), С. 2014 - 2014
Опубликована: Апрель 27, 2024
Polyphenols
are
ubiquitous
plant
metabolites
that
demonstrate
biological
activities
essential
to
plant–environment
interactions.
They
of
interest
food
consumers,
as
well
the
food,
pharmaceutical
and
cosmetic
industry.
The
class
comprises
both
widespread
(chlorogenic
acids,
luteolin,
quercetin)
unique
compounds
diverse
chemical
structures
but
common
biosynthetic
origin.
next
sesquiterpenoids
regarded
major
Inuleae-Inulinae
responsible
for
pharmacological
activity
medicinal
plants
from
subtribe
(Blumea
spp.,
Dittrichia
Inula
Pulicaria
spp.
others).
Recent
decades
have
brought
a
rapid
development
molecular
analytical
techniques
which
resulted
in
better
understanding
taxonomic
relationships
within
Inuleae
tribe
plethora
data
concerning
constituents
Inuleae-Inulinae.
current
taxonomical
classification
has
introduced
changes
well-established
botanical
names
rearranged
genera
based
on
genetic
studies.
newly
created
together
with
earlier
phytochemical
studies
may
provide
some
complementary
information
biochemical
subtribe.
Moreover,
they
at
least
partly
explain
preparations
traditionally
used
therapy.
review
aimed
systematize
knowledge
polyphenols
Inulae-Inulinae.
BMC Complementary Medicine and Therapies,
Год журнала:
2024,
Номер
24(1)
Опубликована: Фев. 2, 2024
Abstract
Citrus
fruit
essential
oil
is
considered
one
of
the
widely
studied
oils
while
its
leaves
attract
less
attention
although
being
rich
in
nearly
same
composition
as
peel
and
flowers.
The
bitter
orange
or
sour
(
aurantium
L.)
were
extracted
using
three
different
techniques
namely;
hydrodistillation
(HD),
steam
distillation
(SD),
microwave-assisted
(MV)
to
compare
their
chemical
composition.
samples
analyzed
through
GC/FID
GC/MS
analyses.
tested
vitro
antioxidant
(DPPH,
ABTS,
CUPRAC,
FRAP,
PBD,
MCA),
neuroprotective
enzyme
inhibitory
activities
(acetylcholine
butyl
choline
enzymes),
antidiabetic
(α-amylase
α-glucosidase).
results
showed
that
thirty-five
volatile
ingredients
detected
quantified.
Monoterpenes
represented
most
abundant
class
followed
by
sesquiterpenes.
C.
carried
potential
activity
where
SD
exhibited
highest
activity,
with
values
arranged
following
order:
FRAP
(200.43
mg
TE/g),
CUPRAC
(138.69
ABTS
(129.49
DPPH
(51.67
TE/g).
also
presented
potent
α-amylase
(0.32)
inhibition
MV
α-glucosidase
(2.73
mmol
ACAE/g),
HD
(2.53
(2.46
ACAE/g).
BChE
AChE
(3.73
2.06
GALAE/g),
respectively).
Thus,
can
act
a
source
antioxidant,
antidiabetic,
for
future
drug
leads.
BMC Complementary Medicine and Therapies,
Год журнала:
2024,
Номер
24(1)
Опубликована: Июль 10, 2024
Bitter
orange
(Citrus
aurantium)
is
a
fruiting
shrub
native
to
tropical
and
subtropical
countries
around
the
world
cultivated
in
many
regions
due
its
nutraceutical
value.
The
current
study
investigated
metabolic
profiling
enzyme
inhibitory
activities
of
volatile
constituents
derived
from
C.
aurantium
peel
Egypt
by
three
different
extraction
methods.
International Journal of Molecular Sciences,
Год журнала:
2025,
Номер
26(8), С. 3902 - 3902
Опубликована: Апрель 20, 2025
β-carotene
(β-C)
is
a
hydrophobic
compound,
easily
degradable
by
light
and
oxygen
with
low
solubility,
limiting
its
applications.
β-cyclodextrin
(β-CD)
can
encapsulate
β-C,
protecting
it
from
degradation
maintaining
bioactivity.
Therefore,
this
research
aimed
to
characterize
determine
the
antioxidant
erythroprotective
activity
of
β-C/β-CD
inclusion
complexes.
The
co-precipitation
technique
was
used
elaborate
in
40:60
ratio,
obtaining
high
yield
(94.10%),
an
entrapment
efficiency
82.47%,
loading
11.92%.
moisture
2.93%.
β-C
release
increased
over
time
216
h
(80.8%,
92.8%,
97.4%
at
8
°C,
25
37
respectively).
A
UV–visible
analysis
confirmed
presence
complex,
indicating
successful
encapsulation
without
significant
structural
changes.
According
adsorption–desorption
isotherms,
complexes
showed
type
II
isotherm.
FT-IR
Raman
spectroscopy
formation
which
interacted
hydrogen
bonds,
interactions,
or
van
der
Waals
forces.
DSC
endothermic
peak
118
°C
β-C/β:CD.
TGA
revealed
reduced
water
loss
β-carotene/β-cyclodextrin
limited
binding
due
encapsulation.
microscopic
surface
morphologies
observed
SEM
were
irregular-shaped
clumps
particle
average
size
8.09
µm.
X-ray
diffraction
crystalline
structure
complex.
zeta
potential
determination
indicated
negative
charge
(−23
−32
mV).
ABTS,
DPPH,
FRAP
demonstrated
β-C/β:CD
(34.09%,
21.73%,
8.85.
mM
ET/g,
respectively),
similar
pure
(34.64%,
22.63%,
9.12
μM
effect
inhibiting
hemolysis
(64.09%).
these
characteristics,
β-CD
good
encapsulant
for
complex
could
be
applied
food
pharmaceutical
industries.
Pharmaceuticals,
Год журнала:
2024,
Номер
17(7), С. 844 - 844
Опубликована: Июнь 27, 2024
In
this
study,
UHPLC-HRMS
analysis
of
the
defatted
methanol
extract
obtained
from
Inula
salicina
L.
led
to
identification
58
compounds—hydroxycinnamic
and
hydroxybenzoic
acids
their
glycosides,
acylquinic
caffeoylhexaric
acids,
flavonoids
glycosides.
addition,
a
new
natural
compound,
N-(8-methylnepetin)-3-hydroxypiperidin-2-one
was
isolated
its
structure
elucidated
by
NMR
spectroscopy.
The
presence
flavoalkaloid
in
genus
is
described
now
for
first
time.
Chlorogenic
acid
main
compound
followed
3,5-,
1,5-
4,5-dicaffeoylquinic
acids.
studied
antioxidant
potential
DPPH,
ABTS,
FRAP
assays
sun
protective
properties.
study
conducted
assess
effectiveness
tested
inhibiting
biofilm
formation
Gram-positive
Gram-negative
strains.
Results
crystal
violet
tests
revealed
notable
decrease
mass
due
extract.
anti-biofilm
efficacy
confirmed
through
observation
viability
live/dead
staining.
results
showed
that
plant
could
be
used
development
cosmetic
products
with
antibacterial
protection
Polyphenols
are
ubiquitous
plant
metabolites
that
demonstrate
biological
activities
essential
to
the
plant-environment
interactions.
They
of
interest
food
consumers,
as
well
food,
pharmaceutical
and
cosmetic
industry.
The
class
comprises
both
widespread
(chlorogenic
acids,
luteolin,
quercetin)
unique
compounds
diverse
chemical
structures
but
common
biosynthetic
origin.
Polyphenols,
next
sesquiterpenoids
regarded
major
Inuleae-Inulinae
responsible
for
pharmacological
activity
medicinal
plants
from
subtribe
(Blumea
spp.,
Dittrichia
Inula
Pulicaria
spp.
others).
Recent
decades
have
brought
a
rapid
development
molecular
analytical
techniques
which
resulted
in
better
understanding
taxonomic
relationships
within
Inuleae
tribe
plethora
data
concerning
constituents
Inuleae-Inulinae.
current
taxonomical
classification
has
introduced
changes
well-established
botanical
names
rearranged
genera
based
on
genetic
studies.
newly
created
together
with
earlier
phytochemical
studies
may
provide
some
complementary
information
biochemical
subtribe.
Moreover,
they
at
least
partly
explain
preparations
traditionally
used
therapy.
review
aimed
systematize
knowledge
polyphenols
Inulae-Inulinae.
Natural Product Research,
Год журнала:
2024,
Номер
unknown, С. 1 - 5
Опубликована: Июль 17, 2024
L.
is
a
desert
aromatic
herb
with
characteristic
fragrance
and
taste
belonging
to
the
family
Asteraceae.
This
study
aimed
evaluate
chemical
composition
of
essential
oil
isolated
from
