Solvent Fractionation and LC-MS Profiling, Antioxidant Properties, and α-Glucosidase Inhibitory Activity of Bombyx batryticatus
Molecules,
Год журнала:
2025,
Номер
30(5), С. 1021 - 1021
Опубликована: Фев. 23, 2025
Bombyx
batryticatus
is
the
dried
body
of
silkworm
(Bombyx
mori
Linnaeus)
larvae
infected
with
Beauveria
bassiana.
It
widely
used
in
traditional
Chinese
medicine
for
treating
convulsions,
epilepsy,
and
hyperglycemia.
In
this
study,
its
extract
were
prepared.
The
total
reducing
power,
hydroxyl
radical
scavenging
superoxide
anion
activities,
as
well
α-glucosidase
inhibitory
activity
superior
to
those
normal
extract.
Among
them,
IC50
value
was
5.76
mg/mL,
while
that
7.0
mg/mL.
Untargeted
metabolomic
analysis
employed
compare
material
composition
batryticatus.
results
revealed
101
metabolic
differences
between
two
groups,
including
a
significant
increase
fatty
acids
their
derivatives
Further
separation
purification
performed
using
solvents
varying
polarity.
chloroform
fraction
exhibited
highest
against
α-glucosidase,
an
0.217
LC-MS
further
identified
compounds
fraction,
suggesting
alkaloids,
acids,
may
be
responsible
strong
activity.
This
study
elucidates
basis
underlying
pharmacological
effects
batryticatus,
particularly
hypoglycemic
components,
thereby
providing
critical
experimental
support
future
development
application
medicine.
Язык: Английский
Optimization of the Microwave-Assisted Extraction Conditions for Phenolic Compounds from Date Seeds
Foods,
Год журнала:
2024,
Номер
13(23), С. 3771 - 3771
Опубликована: Ноя. 25, 2024
Date
seeds,
often
discarded
during
industrial
processing,
are
an
underexploited
by-product
rich
in
polyphenols
with
significant
antioxidant
potential.
This
study
explores
the
extraction
of
from
date
seeds
using
microwave-assisted
(MAE)
organic
solvent.
The
process
was
optimized
response
surface
methodology
(RSM),
focusing
on
time,
ethanol
concentration,
and
temperature.
optimal
conditions
were
46%
(
Язык: Английский