The Effect of Bioactive Aliment Compounds and Micronutrients on Non-Alcoholic Fatty Liver Disease
Antioxidants,
Год журнала:
2023,
Номер
12(4), С. 903 - 903
Опубликована: Апрель 10, 2023
In
the
current
review,
we
focused
on
identifying
aliment
compounds
and
micronutrients,
as
well
addressed
promising
bioactive
nutrients
that
may
interfere
with
NAFLD
advance
ultimately
affect
this
disease
progress.
regard,
targeted:
1.
Potential
NAFLD,
specifically
dark
chocolate,
cocoa
butter,
peanut
butter
which
be
involved
in
decreasing
cholesterol
concentrations.
2.
The
role
of
sweeteners
used
coffee
other
frequent
beverages;
sense,
stevia
has
proven
to
adequate
for
improving
carbohydrate
metabolism,
liver
steatosis,
fibrosis.
3.
Additional
were
shown
exert
a
beneficial
action
namely
glutathione,
soy
lecithin,
silymarin,
Aquamin,
cannabinoids
lower
serum
concentration
triglycerides.
4.
effects
especially
vitamins,
NAFLD.
Even
if
most
studies
demonstrate
vitamins
pathology,
there
are
exceptions.
5.
We
provide
information
regarding
modulation
activity
some
enzymes
related
their
effect
disease.
conclude
can
prevented
or
improved
by
different
factors
through
involvement
signaling,
genetic,
biochemical
pathways
underlie
Therefore,
exposing
vast
knowledge
public
is
particularly
important.
Язык: Английский
Development of dark chocolate with inulin and sweetened with stevia extract obtained by pressurized hot water
Revista colombiana de investigaciones agroindustriales,
Год журнала:
2024,
Номер
11(2), С. 32 - 47
Опубликована: Сен. 2, 2024
Because
of
its
taste,
texture,
and
aroma,
chocolate
is
consumed
as
a
way
to
generate
pleasant
sensations.
Due
high
caloric
density,
moderate
consumption
recommended.
Seeking
offer
the
benefits
this
product
more
selective
public,
aim
research
was
determine
chemical
composition
sensory
properties
sugar-free
dark
added
with
inulin
sweetened
stevia
extract
obtained
by
pressurized
hot
water,
which
compared
commercial
accompanied
analysis
samples.
A
completely
randomized
statistical
experimental
design
used
compare
alternative
chocolates.
The
treatments
were
carried
out
in
triplicate
results
analyzed
descriptive
statistics
one-way
variance
95
%
confidence
level.
showed
that
treatment
leaves
water
allowed
an
extraction
41.51
g
steviol
glycosides
for
rebaudioside
6.76
stevioside
per
100
subjected
processing.
chocolates
indicated
fat
total
dietary
fiber
contents
no
significant
difference
(p
>
0.05)
between
chocolates,
unlike
other
components.
Moisture,
ash,
fat,
protein
slightly
higher
two
types
chocolate,
carbohydrate
content
4.1
lower
than
chocolate.
Both
products
had
0
sugars
(>
37
%),
there
reduction
kcal/100
brand.
Consumer
evaluation
level
liking
<
elaborated
respect
attributes
such
appearance,
color,
texture.
These
findings
suggest
use
extracts
non-caloric
sweetener
healthy,
suitable
people
diabetes.
Язык: Английский
Plasma-Derived Exosomes from NAFLD Patients Modulate the Cannabinoid Receptors’ Expression in Cultured HepaRG Cells
International Journal of Molecular Sciences,
Год журнала:
2023,
Номер
24(2), С. 1739 - 1739
Опубликована: Янв. 16, 2023
Exosomes
produced
by
hepatocytes
upon
lipotoxic
insult
play
a
relevant
role
in
pathogenesis
of
nonalcoholic
fatty
liver
disease
(NAFLD),
suggesting
an
inflammatory
response
the
activation
monocytes
and
macrophages
accelerating
progression.
In
NAFLD
fibrosis,
endogenous
cannabinoids
their
major
receptors
CB1
CB2
appear
to
be
highly
involved.
This
study
aimed
at
evaluating
expression
(CB1R
CB2R)
plasma-derived
exosomes
extracted
from
patients
with
NAFLD,
as
well
investigating
vitro
effects
circulating
cultured
human
HepaRG
cells
following
introduction
into
culture
medium.
The
results
demonstrated
that
are
vehicles
for
transport
CB1R
able
modulate
CB
receptors'
cells.
particular,
drivers
cells,
acting
through
downregulation
CB2R.
Moreover,
upregulation
was
associated
increased
levels
PPAR-γ,
well-known
mediator
tissue
injury.
conclusion,
this
provides
evidence
suggests
mediated
cannabinoid
receptors.
Язык: Английский