ACS Biomaterials Science & Engineering,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 10, 2024
Mussel
refers
to
a
marine
organism
with
strong
adhesive
properties,
and
it
secretes
mussel
adhesion
protein
(MAP).
The
most
vital
feature
of
MAP
is
the
abundance
3,4-dihydroxyphenylalanine
(DOPA)
group
lysine,
which
have
antimicrobial,
anti-inflammatory,
antioxidant,
cell
adhesion-promoting
properties
can
accelerate
wound
healing.
Polydopamine
(PDA)
currently
widely
used
mussel-inspired
material
characterized
by
good
adhesion,
biocompatibility,
biodegradability.
It
mediate
various
interactions
form
functional
coatings
on
cell-material
surfaces.
Nanofibers
based
materials
been
exerting
role
in
repair,
while
there
no
comprehensive
review
presenting
them.
This
Review
introduces
structure
MAPs
their
mechanisms
materials.
Second,
functionalized
modification
inspired
electrospun
nanofibers
application
repair.
Finally,
future
development
direction
coping
strategies
are
discussed.
Moreover,
this
offer
novel
for
repair
bring
about
new
breakthroughs
innovations
tissue
engineering
regenerative
medicine.
Polymers,
Год журнала:
2023,
Номер
15(13), С. 2831 - 2831
Опубликована: Июнь 27, 2023
A
silver-containing
gel
based
on
polyvinyl
alcohol
and
aryloxycyclotriphosphazene
containing
β-carboxyethenylphenoxy
p-formylphenoxy
groups
has
been
developed.
Phosphazene
was
synthesized
via
the
Doebner
reaction
from
hexakis[(4-formyl)phenoxy]cyclotriphosphazene
malonic
acid
characterized
by
1H,
13C,
31P
NMR
spectroscopy
MALDI-TOF
mass
spectrometry.
The
study
of
using
scanning
electron
microscopy
showed
that
contains
open
pores
can
absorb
wound
exudate.
maximum
water
absorption
capacity
272%,
which
reached
after
80
min
testing.
antimicrobial
activity
obtained
evaluated
diffusion
method.
found
to
inhibit
growth
main
microorganisms
in
contact
with
skin:
bacteria
S.
aureus,
P.
aeruginosa,
E.
coli,
B.
subtilis,
epidermidis,
C.
stationis
fungus
albicans.
wound-healing
effect
vivo
a
decrease
area
rabbit
hind
limb
91.43%
(p
<
0.05)
10th
day
observation
content
C-reactive
protein
blood
serum
1.3
times
0.05).
Molecules,
Год журнала:
2024,
Номер
29(9), С. 2050 - 2050
Опубликована: Апрель 29, 2024
Deferoxamine,
an
iron
chelator
used
to
treat
diseases
caused
by
excess
iron,
has
had
a
Food
and
Drug
Administration-approved
status
for
many
years.
A
large
number
of
studies
have
confirmed
that
deferoxamine
can
reduce
inflammatory
response
promote
angiogenesis.
Blood
vessels
play
crucial
role
in
sustaining
vital
life
facilitating
the
delivery
immune
cells,
oxygen,
nutrients,
as
well
eliminating
waste
products
generated
during
cellular
metabolism.
Dysfunction
blood
may
contribute
significantly
development
life-threatening
diseases.
Anti-angiogenesis
therapy
pro-angiogenesis/angiogenesis
strategies
been
frequently
recommended
various
Herein,
we
describe
mechanism
which
promotes
angiogenesis
summarize
its
application
chronic
wounds,
bone
repair,
respiratory
system.
Furthermore,
discuss
drug
system
treating
diseases,
providing
constructive
ideas
inspiration
new
treatment
strategies.
ACS Biomaterials Science & Engineering,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 10, 2024
Mussel
refers
to
a
marine
organism
with
strong
adhesive
properties,
and
it
secretes
mussel
adhesion
protein
(MAP).
The
most
vital
feature
of
MAP
is
the
abundance
3,4-dihydroxyphenylalanine
(DOPA)
group
lysine,
which
have
antimicrobial,
anti-inflammatory,
antioxidant,
cell
adhesion-promoting
properties
can
accelerate
wound
healing.
Polydopamine
(PDA)
currently
widely
used
mussel-inspired
material
characterized
by
good
adhesion,
biocompatibility,
biodegradability.
It
mediate
various
interactions
form
functional
coatings
on
cell-material
surfaces.
Nanofibers
based
materials
been
exerting
role
in
repair,
while
there
no
comprehensive
review
presenting
them.
This
Review
introduces
structure
MAPs
their
mechanisms
materials.
Second,
functionalized
modification
inspired
electrospun
nanofibers
application
repair.
Finally,
future
development
direction
coping
strategies
are
discussed.
Moreover,
this
offer
novel
for
repair
bring
about
new
breakthroughs
innovations
tissue
engineering
regenerative
medicine.
