Effect of transcranial direct current stimulation on postoperative delirium in elderly patients undergoing hip fracture surgery: study protocol for a randomized controlled trial DOI Creative Commons

Li Xue,

Hai-Jie Ji,

Shasha Fan

и другие.

Frontiers in Medicine, Год журнала: 2025, Номер 12

Опубликована: Май 15, 2025

To evaluate the efficacy of transcranial direct current stimulation (tDCS) in reducing incidence postoperative delirium (POD) elderly patients undergoing hip fracture surgery. This single-center, double-blind, randomized controlled trial will enroll 160 participants aged 65 years and older, scheduled for elective surgery under spinal anesthesia. Participants be randomly assigned to either active-tDCS group or sham-tDCS group. The receive two sessions: one pre-surgery post-surgery, with electrodes positioned over left dorsolateral prefrontal cortex right supraorbital area. Each session includes 15-second ramp-up phase at start, 20 min simulation 2 mA ramp-down end. sham procedures no actual delivered. Functional brain activity monitored before after each procedure assess changes cortical activation connectivity using functional near-infrared spectroscopy (fNIRS). primary outcome measure POD, assessed 3-Min Diagnostic Interview Confusion Assessment Method (3D-CAM). Secondary outcomes include severity delirium, pain, anxiety, depression, cognitive function, sleep quality. was registered ClinicalTrials.gov (NCT06678529) on Oct 22, 2024.

Язык: Английский

25 Rehabilitation Measures and Prognosis of Acquired Language Disorders: Aphasia DOI

Katharina Albrecht,

Elisabetta Banco, Charles Ellis

и другие.

European manual of medicine, Год журнала: 2025, Номер unknown, С. 249 - 309

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0

Neural modifications of transtibial prosthesis (TTP) users: an event-related potentials study DOI Creative Commons
Ampika Nanbancha, Weerawat Limroongreungrat, Manunchaya Samala

и другие.

Journal of NeuroEngineering and Rehabilitation, Год журнала: 2025, Номер 22(1)

Опубликована: Март 26, 2025

Abstract Background Individuals with lower-limb amputations are highly dependent upon prostheses to perform daily activities and adapt environmental changes. Transtibial prosthesis (TTP) users in particular, experience greater challenges motor control demonstrate impaired cognitive functions, when compared able-bodied persons. The identification of neural mechanisms underlying adaptation or compensation may contribute the development expansion rehabilitation strategies. Objective To examine neuroplasticity changes transtibial amputees by analyzing event-related potentials (ERPs) obtained from Electroencephalogram (EEG) during Go/No-Go tasks assess adaptations. Methods Twenty-eight TTP twenty-eight persons were recruited. EEG was recorded eyes-open resting states, ERPs a Go/No-go task. Results Our findings that, resting-state, group exhibited no significant differences brain activity across regions. However, task, an increase N2 amplitude observed, reduction P3 noted group. Conclusion These demonstrated modifications individuals amputation, particularly relation inhibitory control, which is essential for effective attentional control. Deficits interfere decision-making processes, thereby impairing execution that require sustained attention flexibility. Based on these adaptions, it be necessary consider targeted interventions aimed at enhancing incorporating specific cortical training strategies users.

Язык: Английский

Процитировано

0

Neuroplasticity and Technology DOI
K. Jayasankara Reddy

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0

Effect of transcranial direct current stimulation on postoperative delirium in elderly patients undergoing hip fracture surgery: study protocol for a randomized controlled trial DOI Creative Commons

Li Xue,

Hai-Jie Ji,

Shasha Fan

и другие.

Frontiers in Medicine, Год журнала: 2025, Номер 12

Опубликована: Май 15, 2025

To evaluate the efficacy of transcranial direct current stimulation (tDCS) in reducing incidence postoperative delirium (POD) elderly patients undergoing hip fracture surgery. This single-center, double-blind, randomized controlled trial will enroll 160 participants aged 65 years and older, scheduled for elective surgery under spinal anesthesia. Participants be randomly assigned to either active-tDCS group or sham-tDCS group. The receive two sessions: one pre-surgery post-surgery, with electrodes positioned over left dorsolateral prefrontal cortex right supraorbital area. Each session includes 15-second ramp-up phase at start, 20 min simulation 2 mA ramp-down end. sham procedures no actual delivered. Functional brain activity monitored before after each procedure assess changes cortical activation connectivity using functional near-infrared spectroscopy (fNIRS). primary outcome measure POD, assessed 3-Min Diagnostic Interview Confusion Assessment Method (3D-CAM). Secondary outcomes include severity delirium, pain, anxiety, depression, cognitive function, sleep quality. was registered ClinicalTrials.gov (NCT06678529) on Oct 22, 2024.

Язык: Английский

Процитировано

0