Innovative approaches for cancer treatment: graphene quantum dots for photodynamic and photothermal therapies

Journal of Materials Chemistry B, Год журнала: 2024, Номер 12(18), С. 4307 - 4334

Опубликована: Янв. 1, 2024

Recent advancements pertaining to the application of GQD-based nanosystems in photothermal and photodynamic cancer therapies are discussed, highlighting crucial challenges, advantages, future perspectives.

Язык: Английский

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Design and numerical simulation of CuBi2O4 solar cells with graphene quantum dots as hole transport layer under ideal and non-ideal conditions

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Янв. 2, 2025

Язык: Английский

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Graphene Quantum Dots from Natural Carbon Sources for Drug and Gene Delivery in Cancer Treatment

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(19), С. 10539 - 10539

Опубликована: Сен. 30, 2024

Cancer therapy is constantly evolving, with a growing emphasis on targeted and efficient treatment options. In this context, graphene quantum dots (GQDs) have emerged as promising agents for precise drug gene delivery due to their unique attributes, such high surface area, photoluminescence, up-conversion biocompatibility. GQDs can damage cancer cells exhibit intrinsic photothermal conversion singlet oxygen generation efficiency under specific light irradiation, enhancing effectiveness. They serve direct therapeutic versatile platforms capable of being easily functionalized various targeting molecules agents. However, challenges achieving uniform size morphology, bandgap engineering, scalability, along minimizing cytotoxicity the environmental impact production, must be addressed. Additionally, there need more comprehensive understanding cellular mechanisms release processes, well improved purification methods. Integrating into existing systems enhances efficacy traditional treatments, offering less invasive options patients. This review highlights transformative potential in while acknowledging that researchers overcome broader application.

Язык: Английский

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Photoactive Dye‐Loaded Polymer Materials: A New Cutting Edge for Antibacterial Photodynamic Therapy

Advanced Functional Materials, Год журнала: 2024, Номер 34(44)

Опубликована: Июль 29, 2024

Abstract Healthcare‐associated infections remain a significant health concern, particularly with the emergence of antibiotic resistance. While these antibiotics have saved countless lives, their overuse reduces efficacy promoting multidrug‐resistant (MDR) bacteria. This prompts researchers to explore new alternatives for treating bacteria proliferation. In this context, antibacterial photodynamic therapy (aPDT) has emerged as promising approach localized infections. It utilizes reactive oxygen species (ROS) oxidative stress agents, thereby minimizing risk developing MDR. The success aPDT significantly hinges on careful selection photosensitizers (PSs) and polymer matrices synthesis polymer‐based photoactive materials. Various light‐absorbing PSs are therefore designed enhancing ROS production antimicrobial efficacy. By incorporating into matrices, materials can harness light power generate ROS, destroying bacterial cells upon irradiation. review aims provide comprehensive overview advancements in field, specifically focusing use mechanism four main generated aPDT, methods used detection, mode action against been outlined. recent improvement also addressed.

Язык: Английский

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Efficiency of Graphene Quantum Dots in Water Contaminant Removal: Trends and Future Research Directions

Water, Год журнала: 2025, Номер 17(2), С. 166 - 166

Опубликована: Янв. 10, 2025

This review explores the efficiency and mechanisms of GQDs in removing contaminants from water, emphasizing their potential for environmental applications. possess unique physicochemical properties, such as a high surface area, tunable photoluminescence, strong adsorption capacities, which enable effective removal diverse contaminants, including heavy metals, organic compounds, dyes. Their electron-hole separation functionalizability enhance reactivity selectivity. Notable findings include integration into advanced nanocomposites supramolecular networks, significantly improving catalytic performance. However, challenges variability synthesis methods, stability under conditions, impact remain. Addressing these limitations understanding interaction between are critical. Future research should prioritize scalable green techniques, long-term assessments, optimized functionalization strategies to establish sustainable solution water purification technologies.

Язык: Английский

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Nitrogen-doped carbon dots/indium-doped zinc sulfide heterostructures for enhanced photocatalytic seawater splitting

Journal of environmental chemical engineering, Год журнала: 2025, Номер unknown, С. 115414 - 115414

Опубликована: Янв. 1, 2025

Язык: Английский

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Graphene Quantum Dots Hybrids in Energy Storage/Conversion Systems—State-of-the-art and Advances

Hybrid Advances, Год журнала: 2025, Номер unknown, С. 100431 - 100431

Опубликована: Март 1, 2025

Язык: Английский

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Utilizing copper-doped graphene quantum dots as a fluorescent sensor for determination of carbamazepine in exhaled breath condensate

Journal of Pharmaceutical and Biomedical Analysis, Год журнала: 2025, Номер 260, С. 116815 - 116815

Опубликована: Март 10, 2025

Язык: Английский

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A holistic review on red fluorescent graphene quantum dots, its synthesis, unique properties with emphasis on biomedical applications

Heliyon, Год журнала: 2024, Номер 10(16), С. e35760 - e35760

Опубликована: Авг. 1, 2024

Graphene quantum dots (GQDs) are an evolving class of carbon-based nanomaterial, seizing tremendous attention owing to their intense optical property, engineered shapes and structures, good photostability. Being a zero-dimensional form carbon structure, GQDs have superior photoluminescent behavior, tunable emission absorption, excellent biocompatibility, low cytotoxicity, hydrophilic nature, modifying surface states. Their water dispersibility functionalized involving heteroatoms various functional groups onto the GQDs, make them particularly suitable for biological applications. Based on absolute luminescence properties, emit blue, green, yellow, red light under ultraviolet irradiation. Amongst three colors, can achieve deeper penetration into tissues, cellular distribution, bio-sensing cell imaging, drug delivery, serves as better candidate photodynamic therapy. The overall objective this review is provide comprehensive overview synthesis methods fluorescence graphene (RF-GQDs), critical comparative analyses spectral techniques used characterization, photoluminescence mechanisms underpinning emission, significance chemically functionalizing GQDs' edges in achieving discussed depth. This also discusses effective applications challenges associated with RF-GQDs examined, providing insights future potential clinical industrial

Язык: Английский

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Development of Graphene-Based Materials with the Targeted Action for Cancer Theranostics

Biochemistry (Moscow), Год журнала: 2024, Номер 89(8), С. 1362 - 1391

Опубликована: Авг. 1, 2024

Язык: Английский

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