Gut virome in inflammatory bowel disease and beyond
Gut,
Год журнала:
2023,
Номер
73(2), С. 350 - 360
Опубликована: Ноя. 10, 2023
The
gut
virome
is
a
dense
community
of
viruses
inhabiting
the
gastrointestinal
tract
and
an
integral
part
microbiota.
coexists
with
other
components
microbiota
host
in
dynamic
equilibrium,
serving
as
key
contributor
to
maintenance
intestinal
homeostasis
functions.
However,
this
equilibrium
can
be
interrupted
certain
pathological
states,
including
inflammatory
bowel
disease,
causing
dysbiosis
that
may
participate
disease
pathogenesis.
Nevertheless,
whether
causal
or
bystander
event
requires
further
clarification.
Язык: Английский
Torque Teno Virus: Lights and Shades
Viruses,
Год журнала:
2025,
Номер
17(3), С. 334 - 334
Опубликована: Фев. 27, 2025
Torque
Teno
Virus
(TTV)
is
a
highly
prevalent
non-pathogenic
DNA
virus
whose
plasma
levels
may
be
related
to
the
host’s
immune
status.
TTV
gained
attention
about
25
years
ago,
but
its
replication
not
fully
understood,
nor
relationship
with
host's
system.
Despite
this
lack
of
knowledge,
currently
being
investigated
as
functional
biomarker
system
in
patients
immunological
damage
and
inflammatory
diseases.
Monitoring
viral
load
over
time
help
clinicians
making
therapeutic
decisions
regarding
immunosuppression
well
likelihood
infectious
complications.
This
review
summarizes
what
we
do
know
enigmatic
virus.
Язык: Английский
Microbiota-associated mechanisms in colorectal cancer
Advances in genetics,
Год журнала:
2024,
Номер
unknown, С. 123 - 205
Опубликована: Янв. 1, 2024
Язык: Английский
Intratumoral microbiota in colorectal cancer: focus on specific distribution and potential mechanisms
Cell Communication and Signaling,
Год журнала:
2024,
Номер
22(1)
Опубликована: Сен. 26, 2024
Язык: Английский
Anelloviruses and Cancer
The Journal of Infectious Diseases,
Год журнала:
2024,
Номер
231(2), С. 298 - 306
Опубликована: Дек. 14, 2024
Anelloviruses
are
among
the
most
prevalent
viruses
within
human
virome,
detected
in
>90%
of
healthy
individuals.
Despite
their
ubiquity,
role
anelloviruses
health
remains
elusive.
This
review
examines
potential
associations
torque
teno
virus
(TTV),
midi
(TTMDV),
and
mini
(TTMV)
with
various
cancers,
highlighting
mixed
conclusions
from
current
epidemiological
studies.
may
modulate
cancer
development
through
abnormal
gene
fusion,
immune
response,
Toll-like
receptor
9
(TLR9)
activation.
On
other
hand,
might
suppress
tumor
formation
TTV-derived
apoptosis-inducing
protein
(TAIP)
NF-κB
signaling
inhibition.
The
high
prevalence
patients
could
also
be
attributed
to
immunocompromised
status
rather
than
a
direct
causative
viruses.
underscores
need
for
more
comprehensive
studies,
including
vitro
vivo
experiments,
clarify
progression.
Язык: Английский