Personalizing Approaches to Management of HPV+ Oropharyngeal Cancer DOI
Fan Zhu, Musaddiq Awan

The Cancer Journal, Год журнала: 2025, Номер 31(3)

Опубликована: Май 1, 2025

HPV+ oropharyngeal cancer represents a unique disease entity in the realm of head and neck with distinct incidence prevalence, pathogenesis, treatment outcome. Management this needs to be personalized consideration combination factors both patient characteristics. Overall outcomes population are excellent. Therefore, late side effects gaining increasing importance attention. Here we present brief overview approaches for population, illustrated by discussion several cases.

Язык: Английский

ASSESSMENT OF FUNCTIONAL OUTCOMES OF TREATMENT IN PATIENTS WITH STAGE III-IV OROPHARYNGEAL CANCER DOI Creative Commons
V.V. Rakhmanov

Clinical and Preventive Medicine, Год журнала: 2025, Номер 2, С. 14 - 22

Опубликована: Апрель 17, 2025

Introduction. Quality of life (QoL) studies in patients with oropharyngeal cancer can assist formulating targeted treatment plans, optimising patient care, and improving follow-up strategies. Aim. To conduct a dynamic prospective study the quality stage III-IV cancer, focusing on assessing long-term functional outcomes. Materials methods. A comprehensive involved clinical morphological examinations, pathohistological immunohistochemical analyses selected biopsy samples, QoL assessments 120 (T3-4N0-3M0-1). These underwent inpatient at ENT-2 (oncology) department Dnipropetrovsk Regional Clinical Hospital named after I.I. Mechnikov, Council, between 2018 2023. was assessed three time points: during treatment, 3- 6-months post-treatment, by bioethical principles using EORTC QLQ-HN43 questionnaire module. Statistical analysis performed Microsoft Excel (https://www.microsoft.com/microsoft-365/free-office-online-for-the-web) R Commander (version 4.2.1 – https://www.R-project.org). Results. Patients who (surgery, radiation therapy, and/or chemotherapy) demonstrated better short-term outcomes 3 months post-treatment compared to those received monotherapy. However, these also exhibited increased levels anxiety. By 6 all experienced significant improvements QoL, including reduced pain improved swallowing function. Comprehensive surgery, chemotherapy, more effective achieving than Despite elevated anxiety levels, strategy showed an overall positive impact both psychosocial aspects patients' QoL. Conclusions. The strategy, grounded examinations analyses, proved be effective. This evidenced particularly terms reduction function, observed post-treatment.

Язык: Английский

Процитировано

0
Commentary on “Predictors of survival among head and neck cancer patients after radiotherapy based on health-related quality of life indices and symptoms-specific outcomes: a systematic review” DOI
Efsun Somay, Erkan Topkan, Uğur Selek

и другие.

Quality of Life Research, Год журнала: 2025, Номер unknown

Опубликована: Май 30, 2025

Язык: Английский

Процитировано

0
Personalizing Approaches to Management of HPV+ Oropharyngeal Cancer DOI
Fan Zhu, Musaddiq Awan

The Cancer Journal, Год журнала: 2025, Номер 31(3)

Опубликована: Май 1, 2025

HPV+ oropharyngeal cancer represents a unique disease entity in the realm of head and neck with distinct incidence prevalence, pathogenesis, treatment outcome. Management this needs to be personalized consideration combination factors both patient characteristics. Overall outcomes population are excellent. Therefore, late side effects gaining increasing importance attention. Here we present brief overview approaches for population, illustrated by discussion several cases.

Язык: Английский

Процитировано

0