CNS Neuroscience & Therapeutics,
Год журнала:
2022,
Номер
28(12), С. 1921 - 1929
Опубликована: Сен. 16, 2022
Immunological
dysfunctions
in
eating
disorders
have
recently
gained
increasing
scientific
attention.
Furthermore,
the
reciprocal
association
between
anorexia
and
autoimmune
diseases
is
of
particular
interest
suggests
a
role
autoimmunity
pathogenesis
disorders.
Anorexia
nervosa
(AN)
are
linked
by
bidirectional
relationship
based
on
common
immunopathological
mechanisms.
In
this
review,
addition
to
reporting
numerous
cases
described
which
associated
with
or
vice
versa,
we
summarize
many
aspects
immune
system
(IS)
AN.
We
describe
how
microbiota
affects
IS,
disrupts
gut-brain
communication,
possibly
triggers
also
shared
immunological
pathways
occurrence
disrupted
T
cell
tolerance
autoantibodies
The
observations
represent
starting
point
for
possible,
future
research
directions.
Current Opinion in Allergy and Clinical Immunology,
Год журнала:
2023,
Номер
23(2), С. 185 - 192
Опубликована: Янв. 11, 2023
Purpose
of
review
This
summarizes
current
evidence
on
the
potential
link
between
severe
acute
respiratory
syndrome
coronavirus
2
(SARS-CoV-2)
infection
and
autoimmunity.
Recent
findings
Several
viral
infections
are
triggers
reactive
autoimmune
diseases
by
inducing
type
II
IV
hypersensitivity
reactions.
demonstrated
that
SARS-CoV-2
is
not
an
exception,
triggering
production
tissue-specific
autoantibodies
during
phase
disease
2019
(COVID-19)
leading
to
development
as
long-term
complication.
The
significant
immune
dysregulation
with
cytokine
storm
organ
damage
observed
in
patients
critical
COVID-19
considered
main
mechanism
explaining
high
levels
autoantibodies,
which
also
implicated
severity
need
for
intensive
care
assessment.
Multisystem
inflammatory
children
(MIS-C)
immune-mediated
where
recent
leads
systemic
inflammation,
already
other
diseases.
Summary
Autoimmunity
may
be
a
complication
SAR-CoV-2
infection.
Understanding
pathogenesis
manifestations
might
help
prevent
incidence
or
exacerbation
disorders
design
better
more
efficient
treatment
strategies
adult
populations.
Rheumatology Science and Practice,
Год журнала:
2024,
Номер
62(1), С. 32 - 54
Опубликована: Фев. 29, 2024
The
pandemic
of
coronavirus
disease
2019
(COVID-19),
etiologically
related
to
the
SARS-CoV-2
virus
(severe
acute
respiratory
syndrome
coronavirus-2),
has
drawn
attention
new
clinical
and
fundamental
problems
in
immunopathology
human
diseases
associated
with
virus-induced
autoimmunity
autoinflammation.
provision
that
“the
experience
gained
rheumatology
process
studying
pathogenetic
mechanisms
pharmacotherapy
immunoinflammatory
rheumatic
as
most
common
severe
forms
autoimmune
autoinflammatory
pathology
humans
will
be
demand
for
deciphering
nature
pathological
processes
underlying
COVID-19
developing
approaches
effective
pharmacotherapy”
was
confirmed
numerous
studies
conducted
over
next
3
years
midst
pandemic.
main
focus
on
a
critical
analysis
data
regarding
role
inflammation,
which
basis
pathogenesis
immune-mediated
context
COVID-19.
Medical Review,
Год журнала:
2024,
Номер
5(1), С. 66 - 75
Опубликована: Июль 1, 2024
Long
COVID,
as
currently
defined
by
the
World
Health
Organization
(WHO)
and
other
authorities,
is
a
symptomatic
condition
that
has
been
shown
to
affect
an
estimated
10
%-30
%
of
non-hospitalized
patients
after
one
infection.
However,
COVID-19
can
also
cause
organ
damage
in
individuals
without
symptoms,
who
would
not
fall
under
current
definition
COVID.
This
damage,
whether
or
not,
lead
various
health
impacts
such
heart
attacks
strokes.
Given
these
observations,
it
necessary
either
expand
COVID
include
recognize
COVID-19-induced
distinct
affecting
many
asymptomatic
infections.
It
important
consider
known
adverse
outcomes,
including
conditions
cancers,
be
until
harm
thresholds
are
reached.
Many
more
medical
identified
testing
than
those
recognized
through
reported
symptoms.
therefore
similarly
while
symptoms
associated
with
there
have
displaying
this
characterization
monitoring
CNS Neuroscience & Therapeutics,
Год журнала:
2022,
Номер
28(12), С. 1921 - 1929
Опубликована: Сен. 16, 2022
Immunological
dysfunctions
in
eating
disorders
have
recently
gained
increasing
scientific
attention.
Furthermore,
the
reciprocal
association
between
anorexia
and
autoimmune
diseases
is
of
particular
interest
suggests
a
role
autoimmunity
pathogenesis
disorders.
Anorexia
nervosa
(AN)
are
linked
by
bidirectional
relationship
based
on
common
immunopathological
mechanisms.
In
this
review,
addition
to
reporting
numerous
cases
described
which
associated
with
or
vice
versa,
we
summarize
many
aspects
immune
system
(IS)
AN.
We
describe
how
microbiota
affects
IS,
disrupts
gut-brain
communication,
possibly
triggers
also
shared
immunological
pathways
occurrence
disrupted
T
cell
tolerance
autoantibodies
The
observations
represent
starting
point
for
possible,
future
research
directions.
