UNSTRUCTURED
The
benefits
and
challenges
of
electronic
health
records
(EHRs)
as
data
sources
for
clinical
epidemiologic
research
have
been
well
described.
However,
several
factors
are
important
to
consider
when
using
EHR
study
novel,
emerging,
multifaceted
conditions
such
postacute
sequelae
SARS-CoV-2
infection
or
long
COVID.
In
this
article,
we
present
opportunities
improve
our
understanding
COVID,
based
on
lessons
learned
from
the
National
Institutes
Health
(NIH)–funded
RECOVER
(REsearching
COVID
Enhance
Recovery)
Initiative,
suggest
steps
maximize
usefulness
performing
research.
The Pediatric Infectious Disease Journal,
Год журнала:
2024,
Номер
43(8), С. 795 - 802
Опубликована: Май 7, 2024
Background:
Cardiopulmonary
exercise
testing
(CPET)
is
a
noninvasive
and
nonexpensive
diagnostic
tool,
that
provides
comprehensive
evaluation
of
the
pulmonary,
cardiovascular,
skeletal
muscle
systems’
integrated
reactions
to
exercise.
CPET
has
been
extensively
used
in
adults
with
Long
COVID
(LC),
while
evidence
about
its
role
children
this
condition
scarce.
Methods:
Prospective,
case-controlled
observational
study.
Children
LC
control
group
healthy
underwent
CPET.
findings
were
compared
within
2
groups,
groups
according
main
clusters
persisting
symptoms.
Results:
Sixty-one
29
controls
included.
Overall,
90.2%
patients
(55
61)
had
pathologic
test
vs
10.3%
(3/29)
control.
presented
statistically
significant
higher
probability
having
abnormal
values
peak
VO2
(
P
=
0.001),
AT%
pred
<0.001),
VO2/HR
%
0.03),
work
slope
0.002),
VE/VCO2
0.01).
The
mean
was
30.17
(±6.85)
34.37
(±6.55)
0.007).
Conclusions:
Compared
controls,
have
objective
impaired
functional
capacity
(expressed
by
low
peak),
signs
deconditioning
cardiogenic
inefficiency
when
assessed
As
such,
should
be
routinely
clinical
practice
objectify
phenotype
limitations
LC,
follow-up
them.
Medicine,
Год журнала:
2024,
Номер
103(12), С. e37502 - e37502
Опубликована: Март 22, 2024
The
incidence
of
long
COVID
in
adult
survivors
an
acute
SARS-CoV-2
infection
is
approximately
11%.
Of
those
afflicted,
26%
have
difficulty
with
day-to-day
activities.
majority
COIVD
cases
occur
after
mild
or
asymptomatic
infection.
Children
can
spread
infections
and
also
develop
long-term
neurological,
endocrine
(type
I
diabetes),
immunological
sequelae.
Immunological
hypofunction
exemplified
by
the
recent
large
outbreaks
respiratory
syncytial
virus
streptococcal
infections.
Neurological
manifestations
are
associated
anatomical
brain
damage
demonstrated
on
scans
autopsy
studies.
prefrontal
cortex
particularly
susceptible.
Common
symptoms
include
fog,
memory
loss,
executive
dysfunction,
personality
changes.
impact
society
has
been
profound.
Fewer
than
half
previously
employed
adults
who
working
full-time,
42%
patients
reported
food
insecurity
20%
difficulties
paying
rent.
Vaccination
not
only
helps
prevent
severe
COVID-19,
but
numerous
studies
found
beneficial
effects
preventing
mitigating
COVID.
There
evidence
that
vaccination
lessen
Physical
occupational
therapy
help
regain
function,
approach
must
be
"low
slow."
Too
much
physical
mental
activity
result
post-exertional
malaise
set
back
recovery
process
days
weeks.
complexity
presentations
coupled
rampant
organized
disinformation,
caused
significant
segments
public
to
ignore
sound
health
advice.
Further
research
needed
regarding
treatment
effective
communication.
Clinical Pediatrics,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 12, 2025
Long
COVID
affects
a
significant
number
of
children,
yet
clinician
knowledge
gaps
and
limited
access
to
specialized
care
hinder
effective
management.
With
fewer
than
20
pediatric
long
clinics
in
the
United
States,
many
families
must
travel
distances
for
care.
To
address
these
challenges,
ECHO
(Extension
Community
Healthcare
Outcomes)
program
was
developed
educate
health
professionals
on
evidence-based
The
engaged
94
participants
from
States
Canada
via
weekly
tele-education
sessions,
recruited
through
word
mouth
professional
listservs.
Pre-surveys
(41%
response
rate)
post-surveys
(29%
were
sent
attendees.
Participants
reported
statistically
improvements
knowledge,
confidence,
competence,
self-efficacy
(
P
<
0.001).
This
represents
valuable
initiative
facilitate
timely
interventions
empower
primary
community
providers
diagnosing,
treating,
managing
populations.
Annals of Clinical Microbiology and Antimicrobials,
Год журнала:
2025,
Номер
24(1)
Опубликована: Апрель 20, 2025
Abstract
Background
Long
COVID
is
a
complex,
heterogeneous
syndrome
affecting
over
four
hundred
million
people
globally.
There
are
few
recommendations,
and
no
formal
training
exists
for
medical
professionals
to
assist
with
clinical
evaluation
management
of
patients
COVID.
More
research
into
the
pathology,
cellular,
molecular
mechanisms
COVID,
treatments
needed.
The
goal
this
work
disseminate
essential
information
about
recommendations
definition,
diagnosis,
treatment,
social
issues
physicians,
researchers,
policy
makers
address
escalating
global
health
crisis.
Methods
A
3-round
modified
Delphi
consensus
methodology
was
distributed
internationally
179
healthcare
professionals,
persons
lived
experience
in
28
countries.
Statements
were
combined
specific
areas:
research,
society.
Results
survey
resulted
187
comprehensive
statements
reaching
strongest
areas
being
diagnosis
assessment,
general
research.
We
establish
conditions
different
subgroups
within
umbrella.
Clear
reached
that
impacts
COVID-19
infection
on
children
should
be
priority,
additionally
need
determine
effects
societies
economies.
it
affects
nervous
system
other
organs
not
likely
observed
initial
symptoms.
note,
biomarkers
critically
needed
these
issues.
Conclusions
This
forms
guidance
spectrum
as
disease
reinforces
translational
large-scale
treatment
trials
protocols.
Journal of Medical Internet Research,
Год журнала:
2024,
Номер
26, С. e50139 - e50139
Опубликована: Апрель 17, 2024
The
COVID-19
pandemic
has
had
a
significant
global
impact,
with
millions
of
cases
and
deaths.
Research
highlights
the
persistence
symptoms
over
time
(post-COVID-19
condition),
situation
particular
concern
in
children
young
people
symptoms.
Social
media
such
as
Twitter
(subsequently
rebranded
X)
could
provide
valuable
information
on
impact
post-COVID-19
condition
this
demographic.
Zeitschrift für Evidenz Fortbildung und Qualität im Gesundheitswesen,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 1, 2024
Against
the
background
of
inadequate
healthcare
provision
for
children
and
adolescents
with
post-COVID-19
syndrome
(PCS),
a
model
project
was
initiated
in
Bavaria
(PoCoKiBa:
Post-COVID
Kids
Bavaria),
offering
specialized
diagnostics
care.
The
aim
this
study
to
explore
describe
experiences
satisfaction
PCS,
as
well
their
parents,
provided
project.
