Cordyceps militaris-Derived Bioactive Gels: Therapeutic and Anti-Aging Applications in Dermatology
Gels,
Год журнала:
2025,
Номер
11(1), С. 33 - 33
Опубликована: Янв. 3, 2025
Cordyceps
militaris
is
a
medicinal
mushroom
widely
utilized
in
traditional
East
Asian
medicine,
recognized
for
its
diverse
therapeutic
properties.
This
review
explores
the
potential
of
C.
militaris-derived
bioactive
gels
applications
dermatology
and
skincare,
with
particular
focus
on
their
anti-aging
benefits.
In
response
to
rising
incidence
skin
cancers
growing
demand
natural
ingredients,
has
emerged
as
valuable
source
functional
compounds,
including
cordycepin,
polysaccharides,
adenosine.
These
compounds
exhibit
multiple
bioactivities,
apoptosis
induction,
cell
cycle
arrest,
anti-inflammatory
effects,
which
have
been
shown
be
particularly
effective
against
melanoma
other
cancers.
Additionally,
antioxidant
properties
enhance
resilience
by
scavenging
reactive
oxygen
species,
reducing
oxidative
stress,
promoting
collagen
synthesis,
thereby
addressing
health
requirements.
The
incorporating
into
gel-based
formulations
skincare
also
examined,
either
standalone
bioactives
or
combination
synergistic
ingredients.
Emphasis
placed
necessity
clinical
trials
standardization
establish
safety,
efficacy,
reproducibility
such
applications.
By
providing
safer
alternative
synthetic
agents,
represent
promising
advancement
skincare.
Язык: Английский
Enhancement of antioxidant activity and total phenolic content of Fomitopsis pinicola mycelium extract
Fungal Biology and Biotechnology,
Год журнала:
2024,
Номер
11(1)
Опубликована: Ноя. 7, 2024
Fomitopsis
pinicola
is
one
of
the
most
common
fungi
found
in
temperate
zone
Europe,
widely
distributed
spread
Asia
and
North
America.
Fungus
has
a
wide
range
therapeutic
activity:
antitumor,
antimicrobial,
anti-inflammatory,
antidiabetic,
antifungal,
hepatoprotective,
hemostatic
action.
A
number
studies
have
confirmed
significant
antioxidant
activity
F.
fruiting
bodies.
However,
controlled
cultivation
conditions
that
influence
fungal
growth
metabolite
production
pinicola,
particularly
mycelial
biosynthesis
metabolites
its
culture
broth,
as
well
mycelium,
remain
poorly
understood.
Язык: Английский
Antibacterial and Antifungal Activity of Metabolites from Basidiomycetes: A Review
Antibiotics,
Год журнала:
2024,
Номер
13(11), С. 1026 - 1026
Опубликована: Окт. 31, 2024
:
The
search
for
new
antimicrobial
molecules
is
important
to
expand
the
range
of
available
drugs,
as
well
overcome
drug
resistance
pathogens.
One
promising
sources
antibacterial
and
antifungal
metabolites
basidial
fungi,
which
have
wide
biosynthetic
capabilities.
Язык: Английский
Effect of the composition of a biologically active dietary supplement with macrofungi mycelia on its antioxidant activity
Regulatory Mechanisms in Biosystems,
Год журнала:
2024,
Номер
15(4), С. 932 - 938
Опубликована: Ноя. 6, 2024
The
global
demand
for
macrofungi
is
driven
by
their
rich
content
of
biologically
active
substances
and
trends
such
as
the
need
natural
medicines,
growing
popularity
vegan
diets,
increased
consumer
interest
in
therapeutic
prophylactic
dietary
supplements,
expanding
use
fungi
food,
pharmaceutical,
cosmetic
industries.
aim
this
study
was
to
investigate
effect
composition
a
supplement
based
on
mixture
macrofungal
mycelium
total
phenolic
antioxidant
activity
supplement.
Fomitopsis
pinicola,
Pleurotus
ostreatus
Trametes
versicolor
were
obtained
through
controlled
submerged
static
cultivation
suitable
media.
powdered
mycelia
F.
P.
ostreatus,
T.
versicolor,
which
are
cubic
plate-shaped
conglomerates
with
rounded
edges,
translucent,
smooth
surface,
mixed
excipients
granulated.
Pharmacotechnological
characteristics
compressibility,
powder
flowability,
moisture
content,
well
dosage
uniformity
disintegration
time
hard
capsules
significantly
varied
depending
granulate
composition.
each
mixture,
selected
granulates,
determined.
Differences
insignificant.
Determination
these
parameters
pharmacotechnological
granulates
allowed
identification
most
excipients:
lactose
monohydrate
(5%),
mannitol:microcrystalline
cellulose
101
ratio
2:1
(10%),
sodium
croscarmellose
(1%),
0.7%
solution
carboxymethyl
(4%).
This
contains
29.83
±
0.49
mg
GAE/g
can
neutralize
DPPH
free
radical
scavenging
86.53
0.62%.
results
confirm
prospects
using
promising
raw
material
development
new
activity.
Язык: Английский