Food Bioscience, Год журнала: 2024, Номер 62, С. 105233 - 105233
Опубликована: Окт. 2, 2024
Язык: Английский
Journal of Ethnopharmacology, Год журнала: 2024, Номер 323, С. 117698 - 117698
Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
5
Journal of Xenobiotics, Год журнала: 2024, Номер 14(4), С. 1378 - 1405
Опубликована: Окт. 2, 2024
Endocrine-disrupting chemicals (EDCs) are chemical substances that can interfere with any hormone action. They categorized according to origin and use, such as industrial like polychlorinated biphenyls (PCBs) polybrominated (PBBs), plastics bisphenol A (BPA), plasticizers phthalates, pesticides dichlorodiphenyltrichloroethane (DDT), fungicides vinclozolin, pharmaceuticals diethylstilbestrol (DES). Natural EDCs, phytoestrogens, present in the diet of both humans animals. Polyphenols a large group natural compounds derived from plants found beverages food. grouped based on their structure into flavonoids nonflavonoids reported have many beneficial effects health, including, but not limited to, anticancer, antioxidant, anti-inflammatory effects. Moreover, polyphenols pro- antioxidant characteristics, due potential, they presumably protective effect against damage induced by EDCs. However, may act In this review, we report regulate activity having positive negative Hence, better understanding associations between EDCs will allow establishment improved approaches protect human health
Язык: Английский
Процитировано
3
Natural Product Communications, Год журнала: 2025, Номер 20(3)
Опубликована: Март 1, 2025
Diabetes mellitus is a long-term metabolic condition marked by chronically high levels of glucose in the blood due to insufficient synthesis insulin or impaired function. Throughout history, several civilizations have used traditional medicinal plants treat and control diabetes. This paper offers thorough review, date, antidiabetic natural compounds origin, specifically highlighting their reported modes mechanisms action therapeutic possibilities, with view fast-tracking possibility transition pharmaceutical products for human use. Phytochemicals such as flavonoids, alkaloids, terpenoids, glycosides notable effects. They been shown via many processes, including boosting secretion, improving sensitivity, blocking absorption \gastrointestinal-tract, regulating carbohydrate metabolism. Unlike earlier reviews, this current one, addition chemistry proposed action, also x-rays effectiveness safety these chemicals combining evidences from laboratory research, animal experiments, clinical trials. Several substances, Demethoxycurcumin, Trigonelline, Ginsenosides, progressed trials, while others like Allicin Polypeptide-p at bedside. Bisdemethoxycurcumin, Vicine, Gymnemosides, are now preclinical trial phase, suggesting that research still ongoing there promise future application. The review highlights evolution diabetes management, potential improve treatment. It suggests incorporating plant-derived into treatments, reducing dependence on drugs adverse
Язык: Английский
Процитировано
0
Frontiers in Nutrition, Год журнала: 2025, Номер 12
Опубликована: Май 20, 2025
This review examines the neurobiological mechanisms by which plant-derived compounds influence women's reproductive health through neuroendocrine-reproductive axis. Gynecological disorders frequently present with neurological manifestations, including cognitive decline in perimenopause, anxiety and depression polycystic ovary syndrome (PCOS), central sensitization endometriosis. Bioactive from medicinal plants, polyphenols phytoestrogens, demonstrate therapeutic potential their anti-inflammatory, antioxidant, neuromodulatory properties. These multi-target offer advantages over conventional single-target therapies simultaneously regulating multiple physiological processes. The explores applications specific gynecological conditions discusses development of dietary supplements functional foods incorporating these ingredients. growing market for products presents opportunities innovative formulations enhanced bioavailability personalized approaches. Future research directions include integrating neuroimaging herbal research, improving clinical translation, establishing regulatory frameworks global application interventions to enhance female health.
Язык: Английский
Процитировано
0
Toxicology and Applied Pharmacology, Год журнала: 2025, Номер 501, С. 117403 - 117403
Опубликована: Май 21, 2025
Язык: Английский
Процитировано
0
Food Bioscience, Год журнала: 2024, Номер 62, С. 105233 - 105233
Опубликована: Окт. 2, 2024
Язык: Английский
Процитировано
0