Traditional Chinese medicine formulae: A complementary method for the treatment of polycystic ovary syndrome

Journal of Ethnopharmacology, Journal Year: 2024, Volume and Issue: 323, P. 117698 - 117698

Published: Jan. 1, 2024

Language: Английский

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Polyphenols Regulate the Activity of Endocrine-Disrupting Chemicals, Having Both Positive and Negative Effects

Journal of Xenobiotics, Journal Year: 2024, Volume and Issue: 14(4), P. 1378 - 1405

Published: Oct. 2, 2024

Endocrine-disrupting chemicals (EDCs) are chemical substances that can interfere with any hormone action. They categorized according to origin and use, such as industrial like polychlorinated biphenyls (PCBs) polybrominated (PBBs), plastics bisphenol A (BPA), plasticizers phthalates, pesticides dichlorodiphenyltrichloroethane (DDT), fungicides vinclozolin, pharmaceuticals diethylstilbestrol (DES). Natural EDCs, phytoestrogens, present in the diet of both humans animals. Polyphenols a large group natural compounds derived from plants found beverages food. grouped based on their structure into flavonoids nonflavonoids reported have many beneficial effects health, including, but not limited to, anticancer, antioxidant, anti-inflammatory effects. Moreover, polyphenols pro- antioxidant characteristics, due potential, they presumably protective effect against damage induced by EDCs. However, may act In this review, we report regulate activity having positive negative Hence, better understanding associations between EDCs will allow establishment improved approaches protect human health

Language: Английский

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Natural Antidiabetic Agents: Current Evidence and Development Pathways from Medicinal Plants to Clinical use

Natural Product Communications, Journal Year: 2025, Volume and Issue: 20(3)

Published: March 1, 2025

Diabetes mellitus is a long-term metabolic condition marked by chronically high levels of glucose in the blood due to insufficient synthesis insulin or impaired function. Throughout history, several civilizations have used traditional medicinal plants treat and control diabetes. This paper offers thorough review, date, antidiabetic natural compounds origin, specifically highlighting their reported modes mechanisms action therapeutic possibilities, with view fast-tracking possibility transition pharmaceutical products for human use. Phytochemicals such as flavonoids, alkaloids, terpenoids, glycosides notable effects. They been shown via many processes, including boosting secretion, improving sensitivity, blocking absorption \gastrointestinal-tract, regulating carbohydrate metabolism. Unlike earlier reviews, this current one, addition chemistry proposed action, also x-rays effectiveness safety these chemicals combining evidences from laboratory research, animal experiments, clinical trials. Several substances, Demethoxycurcumin, Trigonelline, Ginsenosides, progressed trials, while others like Allicin Polypeptide-p at bedside. Bisdemethoxycurcumin, Vicine, Gymnemosides, are now preclinical trial phase, suggesting that research still ongoing there promise future application. The review highlights evolution diabetes management, potential improve treatment. It suggests incorporating plant-derived into treatments, reducing dependence on drugs adverse

Language: Английский

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Dietary supplementation with thymoquinone inhibits rotenone induced developmental toxicity in Drosophila melanogaster: Focus on ovary and larval development

Food Bioscience, Journal Year: 2024, Volume and Issue: 62, P. 105233 - 105233

Published: Oct. 2, 2024

Language: Английский

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