Antimicrobial efficacy of silver nanoparticles against Candida albicans: A systematic review protocol DOI Creative Commons
Razia Z. Adam, Saadika Khan

PLoS ONE, Год журнала: 2021, Номер 16(1), С. e0245811 - e0245811

Опубликована: Янв. 25, 2021

Denture-induced stomatitis is one form of candidiasis. It characterised as inflammation and erythema the oral mucosa underneath denture-bearing areas clinically classified into three types according to severity. Denture hygiene, appropriate mouth rinses use antifungal therapy are commonly used treat condition, but new technologies emerging that may assist in its treatment.The aim this systematic review determine if silver nanoparticles inhibit growth Candida Albicans when included acrylic dentures different denture liners.A protocol was developed published on PROSPERO (Registration No: CRD42019145542) with institutional ethics committee BM20/4/1). The includes all aspects a namely: selection criteria, search strategy, methods using predetermined eligibility data collection, extraction, critical appraisal studies, intended statistical analyses such calculating risk ratios (RR) for dichotomous outcomes presented at 95% confidence intervals, meta-analysis, possible or narrative report needed.With rigorous inclusion criteria set databases identified searching, clinical laboratory studies be obtained results interpretation translation practice challenge these depend quality research.

Язык: Английский

Applications of Silver Nanoparticles in Dentistry: Advances and Technological Innovation DOI Open Access
Clara Couto Fernandéz,

Ana Rita Sokolonski,

Maísa Santos Fonseca

и другие.

International Journal of Molecular Sciences, Год журнала: 2021, Номер 22(5), С. 2485 - 2485

Опубликована: Март 2, 2021

Silver nanoparticles (AgNPs) have been successfully applied in several areas due to their significant antimicrobial activity against microorganisms. In dentistry, AgNP can be disinfection, prophylaxis, and prevention of infections the oral cavity. this work, use silver dentistry associated technological innovations was analyzed. The scientific literature searched using PubMed Scopus databases with descriptors related resulting 90 open-access articles. search for patents restricted A61K code (International Patent Classification), same descriptors, 206 patents. results found were ordered by dental specialties demonstrated incorporation AgNPs different dentistry. context, reaffirmed growth technology dominance USA pharmaceutical industry over product development. It could concluded that nanotechnology is a promising area applications.

Язык: Английский

Процитировано

107

PMMA-Based Nanocomposites for Odontology Applications: A State-of-the-Art DOI Open Access
Ana M. Díez‐Pascual

International Journal of Molecular Sciences, Год журнала: 2022, Номер 23(18), С. 10288 - 10288

Опубликована: Сен. 7, 2022

Polymethyl methacrylate (PMMA), a well-known polymer of the family, is extensively used in biomedicine, particularly odontological applications including artificial teeth, dentures and denture bases, obturators, provisional or permanent crowns, so forth. The exceptional PMMA properties, aesthetics, inexpensiveness, simple manipulation, low density, adjustable mechanical make it perfect candidate field dentistry. However, presents some deficiencies, weakness regarding hydrolytic degradation, poor fracture toughness, lack antibacterial activity. To further enhance its properties solve these drawbacks, different approaches can be performed, incorporation nanofillers. In this regard, types metallic nanoparticles, metal oxide nanofillers, carbon-based nanomaterials have been recently integrated into matrices with aim to reduce water absorption improve their performance, namely thermal flexural properties. review, recent studies development PMMA-based nanocomposites for odontology are summarized future perspectives highlighted.

Язык: Английский

Процитировано

59

Polymeric Dental Nanomaterials: Antimicrobial Action DOI Open Access
Pavel Yudaev, В. П. Чуев,

Bogdan Klyukin

и другие.

Polymers, Год журнала: 2022, Номер 14(5), С. 864 - 864

Опубликована: Фев. 22, 2022

This review aims to describe and critically analyze studies published over the past four years on application of polymeric dental nanomaterials as antimicrobial materials in various fields dentistry. Nanoparticles are promising additives restoration materials. According data, composites based silver nanoparticles, zinc(II), titanium(IV), magnesium(II), copper(II) oxide chitosan calcium phosphate or fluoride nanodiamonds can be used therapy endodontics. Composites with nanoparticles hydroxyapatite bioactive glass proved low efficiency for these fields. The applicable orthodontics include nanodiamonds, titanium(IV) zinc(II) glass, yttrium(III) nanoparticles. periodontics, silver, chitosan, employed implantology prosthetics. also utilized maxillofacial surgery manufacture prostheses. halloysite nanotubes field denture calcium(II) therapeutic dentistry tooth restoration.

Язык: Английский

Процитировано

52

Time to Conquer Fungal Infectious Diseases: Employing Nanoparticles as Powerful and Versatile Antifungal Nanosystems against a Wide Variety of Fungal Species DOI Open Access
Ali Jangjou, Zahra Zareshahrabadi, Milad Abbasi

и другие.

Sustainability, Год журнала: 2022, Номер 14(19), С. 12942 - 12942

Опубликована: Окт. 10, 2022

The development of novel antifungal agents and, in particular, the widespread use these medications over course past two decades, has had a significant impact on treatment fungal infectious diseases. This resulted complete transformation However, antibiotic resistance masked significance such breakthroughs. Antifungal infection with nanoparticles been shown to be effective. As result their unique characteristics, substances, contrast antibiotics purest form, are able exhibit an increased anti-proliferative capacity while requiring lower concentration than traditional drugs do order achieve same effect. Decreased drug effectiveness, minimal tissue penetration throughout tissue, restricted penetration, decreased bioavailability, poor pharmacokinetics, and low water solubility some major factors contributing employment medicines delivery systems. Because this, one primary goals incorporating into varying sorts is reduce negative effects drugs’ inherent qualities. article provides overview many types nanoparticles, as metal, metal oxide, non-metal oxide carbon-based nanostructured lipid carriers, polymeric solid nanofibers, peptides, composites, ZnO quantum dots, that can used systems, well benefits nanomaterials have purified medications.

Язык: Английский

Процитировано

40

Management of Chronic Atrophic Candidiasis (Denture Stomatitis)—A Narrative Review DOI Open Access
Eman Abuhajar, Kamran Ali,

Gulraiz Zulfiqar

и другие.

International Journal of Environmental Research and Public Health, Год журнала: 2023, Номер 20(4), С. 3029 - 3029

Опубликована: Фев. 9, 2023

One of the most common oral diseases affecting people wearing dentures is chronic atrophic candidiasis or denture stomatitis (DS). The aim paper to provide an update on pathogenesis, presentation, and management DS in general dental practice settings. A comprehensive review literature published last ten years was undertaken using multiple databases, including PubMed via MEDLINE, EMBASE, Scopus. eligible articles were analyzed identify evidence-based strategies for DS. Despite its multifactorial nature, leading cause development Candida albicans biofilm, which facilitated by poor hygiene, long-term wear, ill-fitting dentures, porosity acrylic resin dentures. affects between 17 75% population with a slight predominance elderly females. mucosal surfaces posterior tongue are sites DS, affected areas exhibit erythema, swelling palatal mucosa edema. Oral hygiene protocols, adjusting re-fabricating poorly adapting smoking cessation, avoiding nocturnal administration topical systemic antifungals mainstay management. Alternate treatments such as microwave disinfection, phytomedicine, photodynamic therapy, incorporation nanoparticles into resins being evaluated treatment but require further evidence before routine use clinical practice. In summary, inflammatory lesion experienced wearers. Most patients can be managed Effective practitioners may supported thorough understanding recognition awareness contemporary strategies.

Язык: Английский

Процитировано

35

Effect of Denture Base Fabrication Technique on Candida albicans Adhesion In Vitro DOI Open Access

Avi Meirowitz,

Arkadi Rahmanov,

Eti Shlomo

и другие.

Materials, Год журнала: 2021, Номер 14(1), С. 221 - 221

Опубликована: Янв. 5, 2021

Denture stomatitis is a common manifestation of oral candidiasis affecting some 65% denture wearers. This condition initiated by the adherence Candida albicans to base acrylic resin. The present study aimed test in vitro effect traditional and novel fabrication methods on adhesion samples. based discs were fabricated using: (i) computerized milling, (ii) 3D printing, (iii) heat curing, (iv) cold curing. Discs tested for surface roughness (Ra), hydrophobicity (contact angle), mucin adsorption (Bradford assay), adhesion. printing significantly increased microbial cell as compared with milling decreased it. These results associated levels rather than roughness. Results suggest that may increase risk developing stomatitis, whereas decrease it curing fabrication.

Язык: Английский

Процитировано

57

Nanoarchitectonics of Silver/Poly (Methyl Methacrylate) Films: Structure, Optical Characteristics, Antibacterial Activity, and Wettability DOI
Asmaa N. Mohammed Ali, Nadia A. Ali, Seenaa I. Hussein

и другие.

Journal of Inorganic and Organometallic Polymers and Materials, Год журнала: 2023, Номер 33(3), С. 694 - 706

Опубликована: Янв. 12, 2023

Язык: Английский

Процитировано

24

Silver nanoparticles in denture adhesive: An antimicrobial approach against Candida albicans DOI
Laura Catalí Ferreira Peralta, Nara Lígia Martins Almeida, F. M. Pontes

и другие.

Journal of Dentistry, Год журнала: 2023, Номер 131, С. 104445 - 104445

Опубликована: Фев. 10, 2023

Язык: Английский

Процитировано

18

Preparation of Ag-Metal organic frameworks-loaded Sodium Alginate Hydrogel for the treatment of periodontitis DOI Creative Commons
Jinlei Wang, Ke Li, Hang Yuan

и другие.

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Янв. 4, 2025

Periodontitis, a common chronic inflammatory condition caused by bacteria, leads to loss of attachment, resorption alveolar bone, and ultimately tooth loss. Therefore, reducing bacterial load fostering bone regeneration are essential components in the treatment periodontitis. In this study, we prepared smaller-sized Ag-Metal Organic Frameworks (Ag@MOF) loaded with sodium alginate (Alg) hydrogel for periodontitis treatment. The results showed that Ag@MOF smaller particle size was prepared, approximately 5.5 nm. It successfully hindered development Escherichia coli (E.coli) Staphylococcus aureus (S.aureus) disrupting intracellular metabolism, generating ROS, compromising cell membrane integrity, preventing biofilm formation. Ag@MOF/Alg displayed characteristic interconnected three-dimensional structure, along hydrophilic antimicrobial effects. developed greatly enhances invasion migration capabilities endothelial cells, as well promoting angiogenesis. mouse models induced ligature, extent jaw presence cells causing inflammation tissues surrounding teeth were improved group treated hydrogel. levels TNF-α, IL-6, IL-1β significantly reduced compared control group. Conclusion: experimental prove offers new therapeutic approach

Язык: Английский

Процитировано

1

Mechanical and optical properties of additively manufactured denture base resin in different colors modified with antimicrobial substances: An in vitro study DOI
Rafat Sasany, Faris Z. Jamjoom, Burak Yılmaz

и другие.

Journal of Prosthetic Dentistry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

1