Palmatine attenuates the doxorubicin-induced inflammatory response, oxidative damage and cardiomyocyte apoptosis DOI
Dongliang Cheng, Ping Liu, Zhiwei Wang

и другие.

International Immunopharmacology, Год журнала: 2022, Номер 106, С. 108583 - 108583

Опубликована: Фев. 9, 2022

Язык: Английский

Role of sirtuin 1 (SIRT1) in regulation of autophagy and nuclear factor-kappa Beta (NF-ĸβ) pathways in sorafenib-resistant hepatocellular carcinoma (HCC) DOI

Hui-Yin Chan,

Thamil Selvee Ramasamy, Felicia Fei‐Lei Chung

и другие.

Cell Biochemistry and Biophysics, Год журнала: 2024, Номер 82(2), С. 959 - 968

Опубликована: Март 11, 2024

Язык: Английский

Процитировано

6
Emerging Roles of SIRT1 in Alcoholic Liver Disease DOI Creative Commons

Ruixue Ren,

Ziming Wang, Miaomiao Wu

и другие.

International Journal of Biological Sciences, Год журнала: 2020, Номер 16(16), С. 3174 - 3183

Опубликована: Янв. 1, 2020

Alcoholic liver disease (ALD) is the most prevalent type of chronic worldwide with a wide spectrum pathologies ranging from simple steatosis to steatohepatitis, cirrhosis, and even hepatocellular carcinoma. It has been demonstrated that ALD mediated in whole or part by central signaling molecule sirtuin 1 (SIRT1), conserved class III histone deacetylase.SIRT1 plays beneficial roles regulating hepatic lipid metabolism, inhibiting inflammation, controlling fibrosis mediating carcinoma ALD. However, underlying molecular mechanisms are complex remain incompletely understood. The aim this review was highlight latest advances understanding SIRT1 regulatory discuss their unique potential role as novel therapeutic target for treatment.

Язык: Английский

Процитировано

43
Auricularia polytricha and Flammulina velutipes reduce liver injury in DSS-induced Inflammatory Bowel Disease by improving inflammation, oxidative stress, and apoptosis through the regulation of TLR4/NF-κB signaling pathways DOI
Ivan Stève Nguepi Tsopmejio,

Jing Yuan,

Zipeng Diao

и другие.

The Journal of Nutritional Biochemistry, Год журнала: 2022, Номер 111, С. 109190 - 109190

Опубликована: Окт. 19, 2022

Язык: Английский

Процитировано

24
Linagliptin ameliorates acetic acid-induced colitis via modulating AMPK/SIRT1/PGC-1α and JAK2/STAT3 signaling pathway in rats DOI

Mohamed S. El-Ghannam,

Muhammed A. Saad,

Noha N. Nassar

и другие.

Toxicology and Applied Pharmacology, Год журнала: 2022, Номер 438, С. 115906 - 115906

Опубликована: Фев. 3, 2022

Язык: Английский

Процитировано

22
Palmatine attenuates the doxorubicin-induced inflammatory response, oxidative damage and cardiomyocyte apoptosis DOI
Dongliang Cheng, Ping Liu, Zhiwei Wang

и другие.

International Immunopharmacology, Год журнала: 2022, Номер 106, С. 108583 - 108583

Опубликована: Фев. 9, 2022

Язык: Английский

Процитировано

22