Tempe as a control for diabetes mellitus: Consumer perceptions and feasibility

BIO Web of Conferences, Год журнала: 2025, Номер 171, С. 02005 - 02005

Опубликована: Янв. 1, 2025

Tempe is a promising dietary option for diabetes mellitus (DM) sufferers due to its high fiber and low glycemic index. This study aimed assess the nutritional quality of tempe, suitability as high-fiber functional food per PerBPOM No. 1 2022, DM sufferers' perceptions importance. Findings indicated that tempe met Indonesian National Standards moisture, protein, fat, but crude content was above standard (>2.5%). However, standards (≥6 g/100 g). Initially, only 25% respondents considered essential management, after education, 69% recognized importance, demonstrating counselling enhances positive consumption. Age significantly related portion meal, frequency consumption increased with higher expenditure. Education also positively correlated about benefits indicating education were more aware value tempe. condition shows importance public in supporting choice control DM.

Язык: Английский

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Isoflavones and Noncommunicable Diseases: Pharmacological Perspectives

Reference series in phytochemistry, Год журнала: 2025, Номер unknown, С. 323 - 346

Опубликована: Янв. 1, 2025

Язык: Английский

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Dietary flavonoids prevent diabetes through epigenetic regulation: advance and challenge

Critical Reviews in Food Science and Nutrition, Год журнала: 2022, Номер 63(33), С. 11925 - 11941

Опубликована: Июль 11, 2022

The pathophysiology of diabetes has been studied extensively in various countries, but effective prevention and treatment methods are still insufficient. In recent years, epigenetics received increasing attention from researchers exploring the etiology diabetes. DNA methylation, histone modifications, non-coding RNAs play critical roles occurrence, maintenance, progression its complications. Therefore, preventing or reversing epigenetic alterations that occur during development may reduce individual societal burden disease. Dietary flavonoids serve as natural modulators for discovery biomarkers alternative therapies. However, there is limited knowledge about potential beneficial effects on this review, multidimensional different flavonoid subtypes were summarized. Furthermore, it was discussed parental diets might incidence offspring, which represent a promising opportunity to prevent future. Future work will depend anti-diabetic with regulation mechanisms clinical trials.Highlights• "Epigenetic therapy" could diabetic patients• diet" ameliorates diabetes• Targeting regulations by dietary prevention• via transgenerational inheritance.

Язык: Английский

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Effect of Traditional Cooking and In Vitro Gastrointestinal Digestion of the Ten Most Consumed Beans from the Fabaceae Family in Thailand on Their Phytochemicals, Antioxidant and Anti-Diabetic Potentials

Plants, Год журнала: 2021, Номер 11(1), С. 67 - 67

Опубликована: Дек. 26, 2021

The edible beans in Fabaceae have been used for foods and medicines since the ancient time, being more more. It is also appeared as a major ingredient dairy cooking menu many regions including Thailand, rich biodiversity country. Many studies reported on health benefits of their flavonoids, but there no report effect phytochemical profile pharmacological potentials. Thus, this present study aims to complete knowledge, with 10 most consumed by determining impact traditional gastrointestinal digestion phytochemicals, antioxidant anti-diabetic activities using different vitro cellulo yeast models. results showed that Vigna unguiculata subsp. sesquipedalis were richest source whereas population V. mungo, Phaseolus vulgaris, angularis, monomeric anthocyanin contents (MAC). Furthermore, clearly demonstrated plant matrix preservation specific class phytochemicals. In particular, after digestion, total flavonoid (TFC) Glycine max extract was higher than uncooked sample. This first influence inhibition capacity toward advanced glycation end products (AGEs). All samples significant stimulate glucose uptake model, angularis highest capacity. Interestingly, increase both P. vulgaris G. samples. current attempt investigate at effects processes not only natural bioactive compounds Thailand's can be applied agro-industrial phytopharmaceutical sectors.

Язык: Английский

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Association between flavonoid and subclasses intake and metabolic associated fatty liver disease in U.S. adults: Results from National Health and Nutrition Examination Survey 2017–2018

Frontiers in Nutrition, Год журнала: 2022, Номер 9

Опубликована: Дек. 1, 2022

Metabolic associated fatty liver disease (MAFLD) formerly known as non-alcoholic (NAFLD) is the most common chronic disease. Flavonoid considered a promising candidate for metabolic prevention although few studies have explored relationship between flavonoid intake and MAFLD.To assess MAFLD prevalence in U.S. adult population.The data of this cross-sectional study was obtained from National Health Nutrition Examination Survey (NHANES) Food Nutrient Database Dietary Studies (FNDDS) 2017-2018. subclasses assessed by two 24h recalls. diagnosed according to consensus definitions. Multivariate logistic regression model performed examine association with adjustments confounders.A total 4,431 participants were included analysis. had weighted 41.93% not intake. A higher anthocyanin isoflavone intake, on other hand, lower MAFLD. The protective effect significant among male, Non-Hispanic White, Asia participants. Higher risk younger (age < 50), Black, Asia, HEI-2015 scores compared lowest quartile Stratified analysis showed that varied racial groups (Pinteraction = 0.02). positive correlation existed HDL anthocyanidin (P 0.03), whereas negative FPG 0.02).MAFLD adversely linked subclasses, isoflavone. This modifiable lifestyle provides potential opportunity prevent These findings promote future research into links mechanisms

Язык: Английский

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