The regulatory role of microRNAs in common eye diseases: A brief review DOI Creative Commons
Javier A. Benavides‐Aguilar,

Jonathan I. Morales-Rodríguez,

Héctor Ambriz-González

и другие.

Frontiers in Genetics, Год журнала: 2023, Номер 14

Опубликована: Март 29, 2023

MicroRNAs (miRNAs) are highly conserved, small non-coding RNA molecules (∼21 nucleotides) that regulate numerous biological processes, including developmental timing, hematopoiesis, organogenesis, apoptosis, cell differentiation, and proliferation either by mRNA degradation or translation repression. Since eye physiology requires a perfect orchestration of complex regulatory networks, an altered expression key such as miRNAs potentially leads to disorders. In recent years, comprehensive progress has been made in demonstrating the precise roles miRNAs, emphasizing their potential use diagnostic therapeutic purposes chronic human diseases. Thus, this review explicitly illustrates four common disorders, cataract, glaucoma, macular degeneration, uveitis, application disease management.

Язык: Английский

The Role of microRNAs in Epigenetic Regulation of Signaling Pathways in Neurological Pathologies DOI Open Access
П. П. Трегуб, Irada Ibrahimli, Anton S. Averchuk

и другие.

International Journal of Molecular Sciences, Год журнала: 2023, Номер 24(16), С. 12899 - 12899

Опубликована: Авг. 17, 2023

In recent times, there has been a significant increase in researchers’ interest the functions of microRNAs and role these molecules pathogenesis many multifactorial diseases. This is related to diagnostic prognostic potential microRNA expression levels as well prospects using it personalized targeted therapy. review literature analyzes existing scientific data on involvement molecular cellular mechanisms underlying development pathologies such Alzheimer’s disease, cerebral ischemia reperfusion injury, dysfunction blood–brain barrier.

Язык: Английский

Процитировано

10
Role of regulatory non-coding RNAs in traumatic brain injury DOI Creative Commons
Shun Li, Na Qiu, Andrew Ni

и другие.

Neurochemistry International, Год журнала: 2023, Номер 172, С. 105643 - 105643

Опубликована: Ноя. 24, 2023

Язык: Английский

Процитировано

10
Potential role of microRNAs in personalized medicine against hepatitis: a futuristic approach DOI
Sonam Gupta, Shama Parveen

Archives of Virology, Год журнала: 2024, Номер 169(2)

Опубликована: Янв. 21, 2024

Язык: Английский

Процитировано

3
SNHG14 Elevates NFAT5 Expression Through Sequestering miR-375-3p to Promote MPP + -Induced Neuronal Apoptosis, Inflammation, and Oxidative Stress in Parkinson’s Disease DOI
Furong Xu,

Na Bian,

Xuewen Li

и другие.

Neurochemical Research, Год журнала: 2024, Номер 49(5), С. 1212 - 1225

Опубликована: Фев. 21, 2024

Язык: Английский

Процитировано

3
The regulatory role of microRNAs in common eye diseases: A brief review DOI Creative Commons
Javier A. Benavides‐Aguilar,

Jonathan I. Morales-Rodríguez,

Héctor Ambriz-González

и другие.

Frontiers in Genetics, Год журнала: 2023, Номер 14

Опубликована: Март 29, 2023

MicroRNAs (miRNAs) are highly conserved, small non-coding RNA molecules (∼21 nucleotides) that regulate numerous biological processes, including developmental timing, hematopoiesis, organogenesis, apoptosis, cell differentiation, and proliferation either by mRNA degradation or translation repression. Since eye physiology requires a perfect orchestration of complex regulatory networks, an altered expression key such as miRNAs potentially leads to disorders. In recent years, comprehensive progress has been made in demonstrating the precise roles miRNAs, emphasizing their potential use diagnostic therapeutic purposes chronic human diseases. Thus, this review explicitly illustrates four common disorders, cataract, glaucoma, macular degeneration, uveitis, application disease management.

Язык: Английский

Процитировано

8