The regulatory role of microRNAs in common eye diseases: A brief review DOI Creative Commons
Javier A. Benavides‐Aguilar,

Jonathan I. Morales-Rodríguez,

Héctor Ambriz-González

et al.

Frontiers in Genetics, Journal Year: 2023, Volume and Issue: 14

Published: March 29, 2023

MicroRNAs (miRNAs) are highly conserved, small non-coding RNA molecules (∼21 nucleotides) that regulate numerous biological processes, including developmental timing, hematopoiesis, organogenesis, apoptosis, cell differentiation, and proliferation either by mRNA degradation or translation repression. Since eye physiology requires a perfect orchestration of complex regulatory networks, an altered expression key such as miRNAs potentially leads to disorders. In recent years, comprehensive progress has been made in demonstrating the precise roles miRNAs, emphasizing their potential use diagnostic therapeutic purposes chronic human diseases. Thus, this review explicitly illustrates four common disorders, cataract, glaucoma, macular degeneration, uveitis, application disease management.

Language: Английский

The Role of microRNAs in Epigenetic Regulation of Signaling Pathways in Neurological Pathologies DOI Open Access
П. П. Трегуб, Irada Ibrahimli, Anton S. Averchuk

et al.

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(16), P. 12899 - 12899

Published: Aug. 17, 2023

In recent times, there has been a significant increase in researchers’ interest the functions of microRNAs and role these molecules pathogenesis many multifactorial diseases. This is related to diagnostic prognostic potential microRNA expression levels as well prospects using it personalized targeted therapy. review literature analyzes existing scientific data on involvement molecular cellular mechanisms underlying development pathologies such Alzheimer’s disease, cerebral ischemia reperfusion injury, dysfunction blood–brain barrier.

Language: Английский

Citations

10
Role of regulatory non-coding RNAs in traumatic brain injury DOI Creative Commons
Shun Li, Na Qiu, Andrew Ni

et al.

Neurochemistry International, Journal Year: 2023, Volume and Issue: 172, P. 105643 - 105643

Published: Nov. 24, 2023

Language: Английский

Citations

10
Potential role of microRNAs in personalized medicine against hepatitis: a futuristic approach DOI
Sonam Gupta, Shama Parveen

Archives of Virology, Journal Year: 2024, Volume and Issue: 169(2)

Published: Jan. 21, 2024

Language: Английский

Citations

3
SNHG14 Elevates NFAT5 Expression Through Sequestering miR-375-3p to Promote MPP + -Induced Neuronal Apoptosis, Inflammation, and Oxidative Stress in Parkinson’s Disease DOI
Furong Xu,

Na Bian,

Xuewen Li

et al.

Neurochemical Research, Journal Year: 2024, Volume and Issue: 49(5), P. 1212 - 1225

Published: Feb. 21, 2024

Language: Английский

Citations

3
The regulatory role of microRNAs in common eye diseases: A brief review DOI Creative Commons
Javier A. Benavides‐Aguilar,

Jonathan I. Morales-Rodríguez,

Héctor Ambriz-González

et al.

Frontiers in Genetics, Journal Year: 2023, Volume and Issue: 14

Published: March 29, 2023

MicroRNAs (miRNAs) are highly conserved, small non-coding RNA molecules (∼21 nucleotides) that regulate numerous biological processes, including developmental timing, hematopoiesis, organogenesis, apoptosis, cell differentiation, and proliferation either by mRNA degradation or translation repression. Since eye physiology requires a perfect orchestration of complex regulatory networks, an altered expression key such as miRNAs potentially leads to disorders. In recent years, comprehensive progress has been made in demonstrating the precise roles miRNAs, emphasizing their potential use diagnostic therapeutic purposes chronic human diseases. Thus, this review explicitly illustrates four common disorders, cataract, glaucoma, macular degeneration, uveitis, application disease management.

Language: Английский

Citations

8