Process Biochemistry, Год журнала: 2025, Номер unknown
Опубликована: Март 1, 2025
Язык: Английский
Probiotics and Antimicrobial Proteins, Год журнала: 2025, Номер unknown
Опубликована: Янв. 14, 2025
Язык: Английский
Процитировано
8
Food Chemistry Advances, Год журнала: 2025, Номер 6, С. 100919 - 100919
Опубликована: Фев. 11, 2025
Язык: Английский
Процитировано
4
Foods, Год журнала: 2024, Номер 13(23), С. 3886 - 3886
Опубликована: Дек. 1, 2024
Foodborne pathogens are microorganisms that cause illness through contamination, presenting significant risks to public health and food safety. This review explores the metabolites produced by these pathogens, including toxins secondary metabolites, their implications for human health, particularly concerning cancer risk. We examine various such as Salmonella sp., Campylobacter Escherichia coli, Listeria monocytogenes, detailing specific of concern carcinogenic mechanisms. study discusses analytical techniques detecting chromatography, spectrometry, immunoassays, along with challenges associated detection. covers effective control strategies, processing techniques, sanitation practices, regulatory measures, emerging technologies in pathogen control. manuscript considers broader highlighting importance robust policies, awareness, education. identifies research gaps innovative approaches, recommending advancements detection methods, preventive policy improvements better manage foodborne metabolites.
Язык: Английский
Процитировано
10
International Journal of Biological Macromolecules, Год журнала: 2024, Номер 289, С. 138633 - 138633
Опубликована: Дек. 13, 2024
Язык: Английский
Процитировано
9
Molecules, Год журнала: 2025, Номер 30(4), С. 803 - 803
Опубликована: Фев. 9, 2025
Oligosaccharides containing galactosyl moieties belong to two main groups: raffinose family oligosaccharides (RFO, α-GOS) and lactose-type β-galactooligosaccharides (β-GOS), both well-known for their prebiotic effect. The present review investigates the vast amounts of recent research on structures GOS beneficial impact. It focuses molecular interactions between probiotics in vitro vivo, enzymology processes, genetic prerequisites synthesis degradation by probiotic bacteria. preferences strains belonging Bifidobacterium Lactobacillus genera are elucidated form degrade a certain length, structure, linkages monomers. A brief overview industrial production β-GOS natural recombinant included methods efficiency evaluation.
Язык: Английский
Процитировано
1
Pharmaceuticals, Год журнала: 2024, Номер 17(11), С. 1480 - 1480
Опубликована: Ноя. 4, 2024
The intricate relationship between hydrogen sulfide (H2S), gut microbiota, and sirtuins (SIRTs) can be seen as a paradigm axis in maintaining cellular homeostasis, modulating oxidative stress, promoting mitochondrial health, which together play pivotal role aging neurodegenerative diseases. H2S, gasotransmitter synthesized endogenously by specific acts potent modulator of function protecting against damage. Through sulfate-reducing bacteria, microbiota influences systemic H2S levels, creating link health metabolic processes. Dysbiosis, or an imbalance microbial populations, alter production, impair function, increase heighten inflammation, all contributing factors diseases such Alzheimer’s Parkinson’s. Sirtuins, particularly SIRT1 SIRT3, are NAD+-dependent deacetylases that regulate biogenesis, antioxidant defense, inflammation. enhances sirtuin activity through post-translational modifications, sulfhydration, activate pathways essential for mitigating damage, reducing longevity. SIRT1, example, deacetylates NF-κB, pro-inflammatory cytokine expression, while SIRT3 modulates key enzymes to improve energy metabolism detoxify reactive oxygen species (ROS). This synergy is profoundly influenced the levels and, turn, impacts activation. microbiota–H2S–sirtuin also regulating neuroinflammation, plays central pathogenesis Pharmacological interventions, including donors sirtuin-activating compounds (STACs), promise these synergistically, providing novel therapeutic approach conditions. suggests diversity optimal have far-reaching effects on brain health.
Язык: Английский
Процитировано
6
International Journal of Food Sciences and Nutrition, Год журнала: 2024, Номер unknown, С. 1 - 27
Опубликована: Дек. 19, 2024
This comprehensive review examines the impact of dietary patterns on gut microbiome composition and diversity from infancy to old age, linking these changes age-related health outcomes. It investigates how develops across life stages, focusing influence factors. The explores early-life feeding practices, including breastfeeding formula feeding, shape infant microbiota have lasting effects. In elderly individuals, alterations in are associated with increased susceptibility infections, chronic inflammation, metabolic disorders cognitive decline. critical role diet modulating throughout is emphasised, particularly potential benefits probiotics fortified foods promoting healthy ageing. By elucidating mechanisms connecting food systems health, this provides insights into interventions that could enhance resilience improve outcomes lifespan.
Язык: Английский
Процитировано
5
Designed Monomers & Polymers, Год журнала: 2024, Номер 28(1), С. 1 - 34
Опубликована: Дек. 31, 2024
This review paper analyzes recent advancements in bio-polymer coatings for probiotic microencapsulation, with a particular emphasis on chitosan and its synergistic combinations other materials. Probiotic microencapsulation is essential protecting probiotics from environmental stresses, enhancing their stability, ensuring effective delivery to the gut. The begins an overview of highlighting significance safeguarding through processing, storage, gastrointestinal transit. Advances chitosan-based encapsulation are explored, including integration bio-polymers such as alginate, gelatin, pectin, well application nanotechnology innovative techniques like spray drying layer-by-layer assembly. Detailed mechanistic insights integrated, illustrating how influences gut microbiota by promoting beneficial bacteria suppressing pathogens, thus role prebiotic or synbiotic. Furthermore, delves into chitosan's immunomodulatory effects, particularly context inflammatory bowel disease (IBD) autoimmune diseases, describing immune signaling pathways influenced linking changes improvements systemic immunity. Recent clinical trials human studies assessing efficacy chitosan-coated presented, alongside discussion practical applications comparison vitro vivo findings highlight real-world relevance. sustainability sources impact addressed, along novel concept gut-brain axis. Finally, emphasizes future research needs, development personalized therapies exploration techniques.
Язык: Английский
Процитировано
5
The Journal of Nutritional Biochemistry, Год журнала: 2025, Номер unknown, С. 109838 - 109838
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0
Journal of Nutrition, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0