Molecular Crystals and Liquid Crystals,
Год журнала:
2024,
Номер
unknown, С. 1 - 19
Опубликована: Ноя. 27, 2024
Cu(II)
complexes
of
three
Schiff
bases
were
synthesized
and
characterized
via
X-ray
diffraction,
Fourier
transform
infrared,
UV–vis
spectroscopies.
The
act
as
bidentate
ligands,
chelating
ions
in
seesaw
coordination
geometry.
Changing
the
substituent
types
positions
creates
various
non-covalent
interactions
within
crystal
packings,
yielding
notable
topological
differences.
GC–MS
analysis
reveals
that
induce
1.38%–11.43%
efficacy
Suzuki–Miyaura
cross-coupling
reactions.
biological
activity
correlates
with
type
position
aromatic
ring.
one
ethoxy
exhibits
antimicrobial
effects
solely
against
Candida
parapsilosis,
while
those
fluorine
enhance
activity,
particularly
meta
position.
Molecules,
Год журнала:
2025,
Номер
30(2), С. 207 - 207
Опубликована: Янв. 7, 2025
The
scientific
interest
in
the
chemical
modification
of
chitosan
to
increase
its
solubility
and
application
has
led
conjugation
with
Schiff
bases,
which
are
interesting
scaffolds
endowed
diverse
biological
properties.
resultant
chitosan-based
bases
(CSBs)
widely
studied
literature
due
myriad
activities
exerted,
both
catalytic
biological,
including
anticancer,
anti-inflammatory,
antioxidant,
especially
antimicrobial
ones.
Antimicrobial
resistance
(AMR)
is
one
major
public
health
challenges
twenty-first
century
because
it
represents
a
threat
prevention
treatment
growing
number
bacterial,
parasitic,
viral,
fungal
infections
that
no
longer
treatable
available
drugs.
Thus,
this
review,
we
present
brief
outline
CSBs
as
well
their
complexes
metals,
particular
focus
on
recent
regarding
effect
these
captivating
derivatives.
Applied Organometallic Chemistry,
Год журнала:
2025,
Номер
39(3)
Опубликована: Фев. 11, 2025
ABSTRACT
The
complexes
of
Pd
(II),
VO
Cu
and
Ni
(II)
with
Schiff
base
(ABDS)
derived
from
2‐aminobenzothiazole
4‐(diethylamino)salicylaldehyde
have
been
prepared.
Various
spectroscopic
methodologies
for
analysis,
which
might
include
1
H,
13
C
NMR,
infrared
spectra
(IR),
ultraviolet–visible
(UV–vis),
magnetic
values,
applied
to
elucidate
the
construction
these
chemicals.
For
each
complex,
most
suitable
form
has
proposed
as
a
result.
chemical
compound
behaves
bi‐dentate
via
NO
donors
into
material
ions
within
octahedral
shape
about
2+
,
geometry
square
pyramidal
planner
around
ion.
substances
were
tested
against
different
bacterial
fungal
strains.
They
demonstrated
effective
inhibition
harmful
bacteria
under
study
cytotoxic
activity
(IC
50
)
(HCT‐116
cell
line),
(HepG‐2),
(MCF‐7).
metal
chelates
shown
possess
more
antimicrobial
than
free
chelate.
ABDS
ligand
had
only
moderate
antioxidant
activity,
but
combined
forms
V
(IV),
exhibit
ligand.
These
findings
also
corroborated
hypothesis
that
combinations
produced
effects
DPPH
radicals
comparable
those
regular
vitamin
C.
Pharmaceuticals,
Год журнала:
2023,
Номер
16(12), С. 1729 - 1729
Опубликована: Дек. 15, 2023
Poor
responses
to
medical
care
and
the
failure
of
pharmacological
treatment
for
many
high-frequency
diseases,
such
as
cancer
viral
infections,
have
been
widely
documented.
In
this
context,
numerous
metal-based
substances,
including
cisplatin,
auranofin,
various
gold
metallodrugs,
ruthenium
complexes,
are
under
study
possible
anticancer
antiviral
agents.
The
two
Ru(III)
Ru(II)
namely,
BOLD-100
RAPTA-C,
presently
being
studied
in
a
clinical
trial
preclinical
studies
evaluation,
respectively,
Interestingly,
has
also
recently
demonstrated
activity
against
SARS-CoV-2,
which
is
virus
responsible
COVID-19
pandemic.
Over
last
years,
much
effort
dedicated
discovering
new
dual
anticancer-antiviral
Ru-based
complexes
could
be
very
suitable
respect.
Thus,
review
focuses
on
most
recent
regarding
newly
synthesized
use
and/or
Applied Organometallic Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Авг. 31, 2024
ABSTRACT
2‐Aminophenol‐based
Schiff
bases
and
their
metal
complexes
have
drawn
a
lot
of
interest
because
wide
range
biological
activity
uses
in
several
fields.
These
are
synthesized
through
the
condensation
2‐aminophenol
various
carbonyl
compounds,
formed
easily
by
coordinating
with
transition
ions
possess
intriguing
properties
that
rendered
them
promising
candidates
biomedical
research.
compounds
diverse
array
captivating
including
antibacterial,
antifungal,
anticancer,
antioxidant
actions.
Their
versatile
nature
potential
for
tailored
modifications
hold
promise
innovative
applications.
Compared
to
standard
antibiotics
other
studied
C2
,
C8
–
C11
C116
complexes,
along
L16
L17
ligands,
exhibit
highest
antibacterial
activity,
while
C3
C115
demonstrate
antifungal
activity.
The
chelate
formation
ligands
enhanced
antimicrobial
increasing
lipophilic
nature.
C66
C76
C112
L39
ligand
showed
higher
anticancer
than
drugs.
due
improved
permeability
cellular
uptake.
is
related
substituents
base
ligands.
In
containing
an
electron‐withdrawing
group
(e.g.,
Cl
or
Br
NO
2
),
obviously
better
others.
Ligands
L1
L3
L5
L6
L32
demonstrated
most
potent
surpassing
both
conventional
antioxidants.
greater
capability
donating
free
protons
scavenge
radicals.
More
study
needed
fully
explore
2‐aminophenol‐based
development
new
This
review
summarizes
different
synthetic
methods,
activities,
structure–activity
relationship.
aims
conduct
further
research
on
complexes.
Organics,
Год журнала:
2024,
Номер
5(4), С. 395 - 428
Опубликована: Окт. 21, 2024
From
Egyptian
mummies
to
the
Chanel
N°
5
perfume,
aldehydes
have
been
used
for
a
long
time
and
continue
impact
our
senses
in
wide
range
of
perfumes,
foods,
beverages.
Aldehydes
represent
one
categories
volatile
organic
compounds
(VOCs),
which
are
categorized
as
chemicals
with
boiling
points
up
260
°C
can
be
found
indoor
environments
gaseous
phase.
Because
their
potential
or
known
hazardous
properties
humans,
World
Health
Organization
(WHO)-Europe
provided
some
guidelines
that
may
prevent
several
health
risks.
Indeed,
aldehydes,
reported
risky
retired
from
market,
such
butylphenyl
methylpropional
(BMHCA).
The
purpose
this
review
is
summarize
most
important
indoors
outdoors
analyse
depth
toxicological
aspects
these
compounds,
whose
presence
perfumes
often
underestimated.
In
addition,
ingredients’
synonyms
literature
same
compound
were
unified
order
simplify
identification.
Macromol—A Journal of Macromolecular Research,
Год журнала:
2025,
Номер
5(2), С. 15 - 15
Опубликована: Апрель 8, 2025
Antimicrobial
resistance
(AMR)
is
a
major
global
health
problem,
exacerbated
by
the
excessive
and
inappropriate
use
of
antibiotics
in
human
medicine,
animal
care
agriculture.
Therefore,
new
strategies
compounds
are
needed
to
overcome
this
issue.
In
view,
it
may
be
appropriate
reconsider
existing
biomaterials
alleviate
antibiotic
overuse.
Chitin,
naturally
abundant
amino
mucopolysaccharide,
poly-β-1,
4-N-acetylglucosamine
(GlcNAc).
It
white,
hard,
inelastic,
nitrogenous
polysaccharide
source
surface
pollution
coastal
areas.
Chitosan
derives
from
partial
N-deacetylation
chitin
originates
shells
crustaceans
fungi
cell
walls.
nontoxic
natural
antimicrobial
polymer
approved
GRAS
(Generally
Recognized
as
Safe
United
States
Food
Drug
Administration).
Chitin
chitosan,
non-toxic
biopolymers,
useful
for
wastewater
treatment
remove
pollutants,
such
pharmaceuticals,
heavy
metals
dyes.
The
described
features
make
these
biopolymers
intriguing
investigated
their
application
antibacterials.
