Key Considerations during the Transition from the Acute Phase of the COVID-19 Pandemic: A Narrative Review

Vaccines, Год журнала: 2023, Номер 11(9), С. 1502 - 1502

Опубликована: Сен. 19, 2023

The COVID-19 pandemic has been met with an unprecedented response from the scientific community, leading to development, investigation, and authorization of vaccines antivirals, ultimately reducing impact SARS-CoV-2 on global public health. However, is far being eradicated, continues evolve, causes substantial health economic burdens. In this narrative review, we posit essential points its responsible management during transition acute phase pandemic. As discussed, despite Omicron (sub)variant(s) causing clinically milder infections, a negligible pathogen. It requires continued genomic surveillance, particularly if one considers that future (sub)lineages do not necessarily have be milder. Antivirals remain elements in management. former could benefit further development improvements dosing, while seasonal administration latter simplification increase interest tackle vaccine hesitancy. also ensure accessibility pharmaceuticals low-income countries improve understanding their use context long-term goals Regardless location, primary role awareness education must played by healthcare workers, who directly communicate patients serve as models for healthy behaviors.

Язык: Английский

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Changing epidemiology of COVID-19: potential future impact on vaccines and vaccination strategies

Expert Review of Vaccines, Год журнала: 2024, Номер 23(1), С. 510 - 522

Опубликована: Апрель 24, 2024

COVID-19 was an unprecedented challenge worldwide; however, disease epidemiology has evolved, and no longer constitutes a public health emergency of international concern. Nonetheless, remains global threat uncertainties remain, including definition the end pandemic transition to endemicity, understanding true rates SARS-CoV-2 infection/transmission.

Язык: Английский

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The Course of COVID-19 and Long COVID: Identifying Risk Factors among Patients Suffering from the Disease before and during the Omicron-Dominant Period

Pathogens, Год журнала: 2024, Номер 13(3), С. 267 - 267

Опубликована: Март 20, 2024

SARS-CoV-2 has acquired many mutations that influence the severity of COVID-19's course or risk developing long COVID. In 2022, dominant variant was Omicron. This study aimed to compare COVID-19 in periods before and during dominance Omicron variant. Risk factors for COVID were also assessed. based on stationary visits patients after follow-up assessments 3 months. Clinical symptoms, comorbidities, vaccination status evaluated 1967 patients. Of analyzed group, 1308 (66.5%) affected by period dominance. The prevalence significantly lower among group (47.7% vs. 66.9%,

Язык: Английский

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Trends of Hepatitis A Virus Infection in Poland: Assessing the Potential Impact of the COVID-19 Pandemic and War in Ukraine

Viruses, Год журнала: 2024, Номер 16(3), С. 469 - 469

Опубликована: Март 20, 2024

Hepatitis A virus (HAV) is the most common cause of acute viral hepatitis, which preventable by vaccination. This study analyzed trends HAV infections in Poland according to socio-demographic features years 2009–2022 and assessed potential impact COVID-19 pandemic (2020–2023) migration war refugees from Ukraine (since February 2022). In 2009–2022, 7115 new cases infection were diagnosed Poland, especially among men (66.4%) urban areas (77.4%). Infections at age 25–34 (median rate 0.43 per 105) women aged 15–24 0.39 105). Analysis 14-year frequency exhibited three trends, regardless gender, age, residence. The revealed a downward trend 2009–2014, increased significantly 2014–2018, decreased again after 2018. particularly rapid increase occurred between March 2017 2018 0.79 high level persisted until beginning pandemic, point it dropped but did not reach recorded before 2017. During Omicron SARS-CoV-2 dominance period, median was 0.053 105, with four-fold being observed 2022 (when began) August 2022. presented results can serve as reference for further observations Central Europe. epidemiological situation unlikely escalate requires monitoring.

Язык: Английский

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Viral respiratory infections and air pollution: A review focused on research in Poland

Chemosphere, Год журнала: 2024, Номер 359, С. 142256 - 142256

Опубликована: Май 7, 2024

Язык: Английский

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Clinical Characteristics of Hospitalized Children With Coronavirus Disease 2019 After the Spread of the BA.5 Omicron Variants in Japan

The Pediatric Infectious Disease Journal, Год журнала: 2025, Номер unknown

Опубликована: Янв. 21, 2025

Background: The spread of the BA.5 Omicron variant severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has increased number hospitalized children. However, impact new omicron subvariants in children remains poorly described. Methods: This prospective observational study evaluated clinical characteristics with coronavirus disease 2019 (COVID-19) 13 hospitals Niigata, Japan, during September 2022–February 2024. data were divided and compared across 3 periods based on dominant subvariants: BA.5/BF.5/BF.7 period (September 2022–April 2023), XBB/EG.5 (May–December 2023) BA.2.86/JN.1 (January–February 2024). In addition, COVID-19 vaccination rates patients those general population. Results: total, 298 period. patients’ median ages 4.7 years period, 1.2 2.4 peak monthly admissions decreased over time, 44, 32, 19 cases/mo respectively. Dehydration/oral intake failure (37.2%, 111/298) febrile seizures (16.8%, 50/298) predominant reasons for hospitalization. 5–11 age (11.1%) 12–15 (38.9%) significantly lower than population (41.5% 71.0%). Conclusions: Although diminished they continued to pose a risk. Continued efforts are needed protect from this evolving virus.

Язык: Английский

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Effect of COVID-19 vaccination coverage on transmission and mortality during Omicron dominance

Academia Medicine, Год журнала: 2025, Номер 2(1)

Опубликована: Фев. 24, 2025

Background: During the coronavirus disease 2019 (COVID-19) pandemic, emergence of Omicron SARS-CoV2 variant raised concerns about reduction in vaccine effectiveness due to its higher transmissibility. Thus, using ecologic data, we assessed population-level impact COVID-19 vaccination coverage on transmission and mortality, during period dominance globally. Subject methods: We used a longitudinal dataset 110 countries over 16 months (January 2022 April 2023). Applying random-effects regression models, effect monthly full rates newly confirmed cases deaths, adjusting for country characteristics. obtained data from open-access databases, including World Health Organization (WHO) Dashboard Oxford Government Response Tracker. Results: On average, each 1% point increase was associated with 1.4% (95% confidence interval (CI): 0.1%–2.8%, p = 0.035) rate new 5% CI: 3.6%–6.4%, < 0.001) deaths. This protective graded across levels coverage: compared <50% coverage, those coverages 50%–59%, 60%–69%, 70%–79%, ≥80% had 20.5% –16.4%–45.7%), 53.8% (22.6%–72.5%), 54.3% (15.5%–75.3%), 69.6% (38.7%–84.9%) lower cases, respectively, average. Conclusions: Our findings suggest an important role mitigating pandemics, particularly despite highly transmissible variants like Omicron.

Язык: Английский

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Management of SARS-CoV-2 Infection-Clinical Practice Guidelines of the Polish Association of Epidemiologists and Infectiologists, for 2025

Journal of Clinical Medicine, Год журнала: 2025, Номер 14(7), С. 2305 - 2305

Опубликована: Март 27, 2025

The first Polish recommendations for the management of COVID-19 were published by Society Epidemiologists and Infectiologists (PTEiLChZ) on 31 March 2020, last three years ago. emergence new SARS-CoV-2 variants, a different course disease, as well knowledge about therapies vaccines, requires updating diagnostic, therapeutic, prophylactic guidelines. Despite reduction in threat associated with COVID-19, there is risk another epidemic caused coronaviruses, which was an additional reason developing version In preparing these recommendations, Delphi method used, reaching consensus after survey cycles. Compared to 2022 version, names individual stages disease have been changed, adapting them realities clinical practice, attention paid differences observed immunosuppressed patients children. Some previously recommended drugs discontinued, including monoclonal antibodies. addition, general principles vaccination presented, issues related post-COVID syndrome.

Язык: Английский

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Differences in Clinical Presentation of COVID-19 in Children Hospitalized During Domination of Early (BA.1, BA.2) and Late (BA.5, BA.2.75, BQ.1 and XBB.1.5) SARS-CoV-2 Omicron Subvariants

The Pediatric Infectious Disease Journal, Год журнала: 2023, Номер 43(2), С. 149 - 154

Опубликована: Ноя. 3, 2023

This study analyzed data for 1098 children: 575 diagnosed with COVID-19 between January and June 2022 (early Omicron) 523 hospitalized from July to April 2023 (late Omicron). New Omicron subvariants lead similar recovery rates without deaths acute respiratory distress syndrome in children as BA.1 BA.2, however, they more often cause fever croup. Children suffering comorbidities, presenting pulmonary lesions older, may be prone a severe consequences of terms the currently dominating subvariants.

Язык: Английский

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Impact of the COVID-19 and War Migration on HIV/AIDS Epidemiology in Poland

Journal of Clinical Medicine, Год журнала: 2024, Номер 13(14), С. 4106 - 4106

Опубликована: Июль 13, 2024

Objectives: This study analyzed trends in HIV/AIDS Poland over the time period of 2009–2021 and potential impact COVID-19 migration war refugees from Ukraine. Methods: Long-term were assessed by joinpoint regression using data Polish registries. The burden was also compared before during pandemic refugee migration. Results: In 2009–2021, upward tendency rate new HIV infections until 2017 decrease after accompanied a downward trend diagnoses mortality. From pandemic’s beginning March 2022, rates dramatically decreased to later increase pre-pandemic levels, which partially coincided with wave Conclusions: analysis showed related mortality 2009–2021. While has reduced number detected cases, subsequent 2022 may be lifting restrictions refugees’ These observations have implications for WHO European Region, seeking end AIDS as public health problem 2030.

Язык: Английский

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