Polymers,
Год журнала:
2022,
Номер
14(15), С. 2994 - 2994
Опубликована: Июль 24, 2022
The
medicinal
administration
of
Aloe
vera
gel
has
become
promising
in
pharmaceutical
and
cosmetic
applications
particularly
with
the
development
nanotechnology
concept.
Nowadays,
effective
H.
pylori
treatment
is
a
global
problem;
therefore,
natural
products
nanopolymers
such
as
chitosan
nanoparticles
(CSNPs)
could
represent
novel
strategy
for
gastric
infection
pylori.
HPLC
analysis
A.
indicated
presence
chlorogenic
acid
main
constituent
(1637.09
µg/mL)
other
compounds
pyrocatechol
µg/mL),
catechin
(1552.92
naringenin
(528.78
rutin
(194.39
quercetin
(295.25
cinnamic
(37.50
µg/mL).
CSNPs
incorporated
were
examined
via
TEM,
indicating
mean
sizes
83.46
nm
36.54
nm,
respectively.
FTIR
spectra
showed
various
different
functional
groups
CSNPs,
gel,
CSNPs.
Two
strains
inhibited
using
inhibition
zones
16
16.5
mm,
while
exhibited
highest
28
30
resistant
sensitive
strains,
minimal
inhibitory
concentration
(MIC)
was
15.62
3.9
µg/mL,
bactericidal
(MBC)
15.60
7.8
µg/mL
MBC/MIC
1
2
indexes
respectively,
against
resistance
strain.
DPPH
Scavenging
(%)
antioxidant
activity
an
IC50
138.82
μg/mL
A.vera
extract,
81.7
when
enhanced
hemolysis
compared
to
alone.
Molecular
docking
studies
through
interaction
components
crystal
structure
(4HI0)
protein
supported
results
anti-H.
activity.
Frontiers in Pharmacology,
Год журнала:
2024,
Номер
15
Опубликована: Авг. 8, 2024
Silver
nanoparticles
(AgNPs)
have
gained
significant
attention
in
biomedical
applications
due
to
their
unique
physicochemical
properties.
This
review
focuses
on
the
roles
of
AgNPs
antimicrobial
activity,
anticancer
therapy,
and
wound
healing,
highlighting
potential
address
critical
health
challenges.
Polymers,
Год журнала:
2022,
Номер
14(15), С. 2994 - 2994
Опубликована: Июль 24, 2022
The
medicinal
administration
of
Aloe
vera
gel
has
become
promising
in
pharmaceutical
and
cosmetic
applications
particularly
with
the
development
nanotechnology
concept.
Nowadays,
effective
H.
pylori
treatment
is
a
global
problem;
therefore,
natural
products
nanopolymers
such
as
chitosan
nanoparticles
(CSNPs)
could
represent
novel
strategy
for
gastric
infection
pylori.
HPLC
analysis
A.
indicated
presence
chlorogenic
acid
main
constituent
(1637.09
µg/mL)
other
compounds
pyrocatechol
µg/mL),
catechin
(1552.92
naringenin
(528.78
rutin
(194.39
quercetin
(295.25
cinnamic
(37.50
µg/mL).
CSNPs
incorporated
were
examined
via
TEM,
indicating
mean
sizes
83.46
nm
36.54
nm,
respectively.
FTIR
spectra
showed
various
different
functional
groups
CSNPs,
gel,
CSNPs.
Two
strains
inhibited
using
inhibition
zones
16
16.5
mm,
while
exhibited
highest
28
30
resistant
sensitive
strains,
minimal
inhibitory
concentration
(MIC)
was
15.62
3.9
µg/mL,
bactericidal
(MBC)
15.60
7.8
µg/mL
MBC/MIC
1
2
indexes
respectively,
against
resistance
strain.
DPPH
Scavenging
(%)
antioxidant
activity
an
IC50
138.82
μg/mL
A.vera
extract,
81.7
when
enhanced
hemolysis
compared
to
alone.
Molecular
docking
studies
through
interaction
components
crystal
structure
(4HI0)
protein
supported
results
anti-H.
activity.