Biotechnology Notes,
Год журнала:
2024,
Номер
5, С. 64 - 79
Опубликована: Янв. 1, 2024
Nanotechnology
has
the
advantages
of
enhanced
bioactivity,
reduced
toxicity,
target
specificity,
and
sustained
release
NPs
can
penetrate
cell
membranes.
The
small
size
silver
nanoparticles,
AgNPs,
large
surface
area,
unique
physicochemical
properties
contribute
to
lysis
increased
permeability
membranes
used
in
field
biomedicine.
Functional
precursors
integrate
with
phytochemicals
create
distinctive
therapeutic
stability
nanoparticles
be
by
Surface
coatings
encapsulation
methods,
current
study
explores
various
synthesis
methods
characterization
techniques
(AgNPs)
highlights
their
intrinsic
activity
applications,
Anti-cancer
noted
at
a
concentration
range
5-50
μg/ml
angiogenesis
is
mitigated
dosage
10-50
μg/ml,
Diabetes
controlled
within
same
concentration.
Wound
healing
improved
concentrations
typical
10-08
for
bacteria
antimicrobial
capabilities.
Advancement
focus
on
future
use
AgNPs-coated
wound
dressings
medical
devices
decrease
risk
infection.
Chemotherapeutic
drugs
administered
which
reduces
adverse
effects
an
improvement
treatment
outcomes.
AgNPs
have
been
found
improve
proliferation
differentiation,
making
them
beneficial
tissue
engineering
regenerative
medicine.
Our
emerging
patterns
developments
medicine,
inferring
potential
paths.
Nanomaterials,
Год журнала:
2024,
Номер
14(18), С. 1527 - 1527
Опубликована: Сен. 20, 2024
Recently,
silver
nanoparticles
(NPs)
have
attracted
significant
attention
for
being
highly
desirable
nanomaterials
in
scientific
studies
as
a
result
of
their
extraordinary
characteristics.
They
are
widely
known
effective
antibacterial
agents
that
capable
targeting
wide
range
pathogens.
Their
distinct
optical
characteristics,
such
localized
surface
plasmon
resonance,
enlarge
utilization,
particularly
the
fields
biosensing
and
imaging.
Also,
capacity
to
control
charge
modify
them
using
biocompatible
substances
offers
improved
durability
specific
interactions
with
biological
systems.
Due
exceptional
stability
minimal
chemical
reactivity,
NPs
suitable
diverse
array
applications.
These
produced
through
chemical,
biological,
physical
processes,
each
which
has
advantages
disadvantages.
Chemical
techniques
often
encounter
issues
complicated
purification,
reactive
substances,
excessive
energy
usage.
However,
eco-friendly
approaches
exist,
even
though
they
require
longer
processing
times.
A
key
factor
affecting
stability,
size
distribution,
purity
is
synthesis
process
selected.
This
review
focuses
on
how
essential
it
choose
appropriate
method
order
optimize
characteristics
use
NPs.
Frontiers in Pharmacology,
Год журнала:
2024,
Номер
15
Опубликована: Авг. 8, 2024
Silver
nanoparticles
(AgNPs)
have
gained
significant
attention
in
biomedical
applications
due
to
their
unique
physicochemical
properties.
This
review
focuses
on
the
roles
of
AgNPs
antimicrobial
activity,
anticancer
therapy,
and
wound
healing,
highlighting
potential
address
critical
health
challenges.
Nanomaterials,
Год журнала:
2023,
Номер
13(18), С. 2566 - 2566
Опубликована: Сен. 15, 2023
Cancer
is
one
of
the
leading
causes
death
worldwide.
Because
each
person’s
cancer
may
be
unique,
diagnosing
and
treating
challenging.
Advances
in
nanomedicine
have
made
it
possible
to
detect
tumors
quickly
investigate
tumor
cells
at
a
cellular
level
contrast
prior
diagnostic
techniques.
Quantum
dots
(QDs)
are
functional
nanoparticles
reported
useful
for
diagnosis.
QDs
semiconducting
tiny
nanocrystals,
2–10
nm
diameter,
with
exceptional
optoelectronic
properties
that
can
tailored
sensitively
report
on
their
environment.
This
review
highlights
these
synthesis
methods
when
used
diagnostics.
The
conjugation
reporting
or
binding
molecules
QD
surface
discussed.
summarizes
most
recent
advances
using
vitro
imaging,
vivo
targeted
drug
delivery
platforms
applications.
Pharmaceutics,
Год журнала:
2023,
Номер
15(7), С. 1932 - 1932
Опубликована: Июль 11, 2023
Currently,
there
are
many
studies
on
the
application
of
nanotechnology
in
therapy.
Metallic
nanoparticles
promising
nanomaterials
cancer
therapy;
however,
functionalization
these
with
biomolecules
has
become
relevant
as
their
effect
cells
is
considerably
increased
by
photothermal
and
photodynamic
therapies,
drug
nanocarriers,
specificity
antibodies,
resulting
new
therapies
that
more
specific
against
different
types
cancer.
This
review
describes
functionalized
palladium,
gold,
silver
platinum
treatment
cancer,
themselves
show
an
anticancer
effect.
further
enhanced
when
NPs
either
DNA,
RNA,
peptides,
proteins,
or
folic
acid
other
molecules.
These
can
penetrate
cell
accumulate
tumor
tissue,
a
cytotoxic
through
generation
ROS,
induction
apoptosis,
cycle
arrest,
DNA
fragmentation,
NP-based
therapy
strategy
be
used
synergistically
chemotherapy
radiotherapy
to
achieve
effective
reduce
side
effects.
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Май 22, 2024
Abstract
Silver
nanoparticles
(AgNPs)
have
gained
much
attention
due
to
their
unique
physical,
and
chemical
properties.
Integration
of
phytochemicals
in
nanoformulation
might
higher
applicability
healthcare.
Current
work
demonstrates
the
synthesis
green
AgNPs
with
O.
gratissimum
(gr-AgNPs)
tenuiflorum
(te-AgNPs)
americanum
(am-AgNPs)
followed
by
an
evaluation
antimicrobial
anticancer
SEM
analysis
revealed
spherical-shaped
particles
average
particle
sizes
69.0
±
5
nm
for
te-AgNPs,
46.9
9
gr-AgNPs,
58.5
18.7
am-AgNPs
a
polydispersity
index
below
0.4.
The
synthesized
effectively
inhibited
Klebsiella
pneumonia
,
Escherichia
coli
Staphylococcus
aureus,
Aspergillus
niger,
Candida
albicans
23
1.58
mm,
20
1.68
22
1.80
26
1.85
1.40
zone
inhibition
respectively
.
Synthesized
also
induced
apoptotic
cell
death
MCF-7
concentration-dependent
manner.
IC
50
values
am-AgNPs,
gr-AgNPs
were
14.78
0.89
µg,
18.04
0.63
15.41
0.37
µg
which
suggested
that
most
effective
against
cancer.
At
dose
size
(20
µg)
equally
commercial
standard
Doxorubicin
(DOX).
In
comparison
te-AgNPs
vitro
effects.
reported
Ocimum
its
properties
profile
(GCMS)
compared
it
earlier
species.
activity
microbial
pathogens
selected
cancer
cells
clearly
depicted
these
species
distinct
variations
activity.
results
emphasized
on
potential
biogenic
silver
healthcare
but
before
formulation
products,
detailed
is
required
human
animal
models.
RSC Advances,
Год журнала:
2024,
Номер
14(6), С. 4074 - 4088
Опубликована: Янв. 1, 2024
Fungal
endophytes
are
a
putative
source
of
bioactive
metabolites
that
have
found
significant
applications
in
nanomedicine
due
to
their
metabolic
versatility.
In
the
present
study,
an
aqueous
extract
fungal
endophyte,
International Journal of Nanomedicine,
Год журнала:
2024,
Номер
Volume 19, С. 4451 - 4464
Опубликована: Май 1, 2024
Introduction:
Researchers
are
increasingly
favouring
the
use
of
biological
resources
in
synthesis
metallic
nanoparticles.
This
process
is
quick
and
affordable.
The
current
study
examined
antibacterial
anticancer
effects
silver
nanoparticles
(AgNPs)
derived
from
Neurada
procumbens
plant.
Biomolecules
natural
sources
can
be
used
to
coat
AgNPs
make
them
biocompatible.
Methods:
UV-Vis
spectroscopy
was
verify
plant
extract,
while
transmission
electron
microscopy
(TEM),
photoluminescence
(PL)
spectroscopy,
dynamic
light
scattering
(DLS),
Fourier
transform
infrared
(FTIR)
were
characterize
their
morphology,
crystalline
structure,
stability,
coating.
Results:
UV-visible
spectrum
shows
an
absorption
peak
at
422
nm,
indicating
isotropic
nature
these
As
a
result
emergence
804.53
615.95
cm
−
1
emitted
by
atoms
sample,
FTIR
demonstrated
that
Ag
stretching
vibration
mode
metal-oxygen
(M-O).
Electron
dispersive
X-ray
(EDX)
spectral
analysis
elementary
has
3
keV.
Irradiating
surface
with
electrons,
photons,
or
laser
beams
triggers
illumination.
emission
locations
have
been
found
between
300
550
nm.
DLS
analysis,
suspended
particles
showed
bimodal
size
distribution,
Z-average
particle
being
93.38
Conclusion:
findings
action
substantially
(
p
≤
0.05)
more
evident
against
Gramme-positive
strains
(S.
aureus
B.
cereus)
than
E.
coli
.
biosynthesis
environmentally
friendly
method
for
making
nanostructures
antimicrobial
properties.
Keywords:
Silver
nanoparticles,
peak,
