Heliyon, Год журнала: 2024, Номер 11(1), С. e41152 - e41152
Опубликована: Дек. 12, 2024
Язык: Английский
Discover Chemistry., Год журнала: 2025, Номер 2(1)
Опубликована: Март 17, 2025
Язык: Английский
Процитировано
1
Bioorganic Chemistry, Год журнала: 2025, Номер unknown, С. 108228 - 108228
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0
Pharmacia, Год журнала: 2025, Номер 72, С. 1 - 10
Опубликована: Фев. 19, 2025
Background : Marine ecosystems are a vast reservoir of bioactive compounds with immense pharmacological potential. Objectives This review explores the molecular mechanisms action, potential therapeutic applications, and challenges in clinical translation marine-derived molecules targeting immune pathways. Methods A comprehensive literature was conducted, analyzing studies on immunomodulatory effects polysaccharides, peptides, secondary metabolites. Result In recent years, derived from marine organisms, such as metabolites, have shown promise modulators responses. These interact pathways to enhance or suppress functions, making them valuable for treating diseases ranging infections autoimmune disorders cancer. Conclusion Marine-derived exhibit significant agents by various However, further research is required optimize their applications address translation.
Язык: Английский
Процитировано
0
International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(7), С. 3203 - 3203
Опубликована: Март 30, 2025
Steroids have been pivotal in medicine and biology, with research into their therapeutic potential accelerating over the past few decades. This review examines recent steroid discoveries from marine terrestrial sources, highlighting both novel compounds those newly identified biological activities. The structural diversity of these steroids contributes to wide range activity, including anticancer, antimicrobial, antidiabetic, anti-inflammatory, immunomodulatory properties. Particular emphasis is placed on derived invertebrates, fungi, medicinal plants, which shown promising potential. Advances analytical techniques such as NMR spectroscopy mass spectrometry facilitated identification compounds. These findings emphasize growing importance addressing pressing global health issues, particularly antibiotic resistance cancer, where new strategies are urgently needed. Although many exhibit potent bioactivity, challenges remain translating clinical therapies. Ongoing exploration natural along application modern synthetic computational methods, will be crucial unlocking full steroid-based
Язык: Английский
Процитировано
0
International Journal of Translational Medicine, Год журнала: 2024, Номер 4(4), С. 740 - 781
Опубликована: Дек. 6, 2024
The increase in cancer incidence recent years necessitates urgent exploration of novel and alternative sources natural bioactives for targeted therapy. Approximately 75% the Earth’s surface is covered by oceans, which are thought to harbor untapped physiologically active compounds with potential efficacy against cancer. Recently, a growing focus has been on isolating investigating bioactive derived from marine sources. Bioactive metabolites diverse chemical structures, isolated various species such as algae, mollusks, actinomycetes, demonstrate wide range cancers. To our knowledge, this one articles that reviewed papers application marine-derived This study aims showcase some most current developments therapy have identified
Язык: Английский
Процитировано
3
Heliyon, Год журнала: 2024, Номер 11(1), С. e41152 - e41152
Опубликована: Дек. 12, 2024
Язык: Английский
Процитировано
0