International Journal of Gynecology & Obstetrics, Год журнала: 2023, Номер 162(1), С. 6 - 12
Опубликована: Фев. 21, 2023
Язык: Английский
Journal of Obstetrics and Gynaecology, Год журнала: 2023, Номер 43(1)
Опубликована: Янв. 18, 2023
Pregnant women are one of the endangered groups who need special attention in COVID-19 epidemic. We conducted a systematic review and summarised studies that reported adverse pregnancy outcomes pregnant with infection. A literature search was performed PubMed Scopus up to 1 September 2022, for retrieving original articles published English language assessing association between infection outcomes. Finally, this study, 1790 obtained initial search, 141 eligible including 1,843,278 were reviewed. also meta-analysis total 74 cohort case-control studies. In meta-analysis, both fixed random effect models used. Publication bias assessed by Egger's test trim fill method case significant result, adjust bias. The result showed pooled prevalence preterm delivery, maternal mortality, NICU admission neonatal death group significantly more than those without (p<.01). meta-regression using income level countries. during may cause death. Pregnancy loss SARS-CoV2 positive neonates Lower middle higher High income. Vertical transmission from mother foetus occur, but its immediate long-term effects on newborn unclear.
Язык: Английский
Процитировано
48
Vaccines, Год журнала: 2022, Номер 10(2), С. 275 - 275
Опубликована: Фев. 10, 2022
Universal COVID-19 immunization is seen as a critical approach for limiting the spread of SARS-CoV-2 and reducing danger new variations emerging in general population, especially pregnant women. The literature accessible research data indicate that vaccination intentions vary greatly by country, with Romania ranking among European nations lowest rates. Thus, we aimed to investigate prevalence extent vaccine hesitancy women factors influencing their decision. A cross-sectional study was conducted on referred Obstetrics Gynecology Clinic Timisoara Municipal Emergency Hospital Romania. Participants were asked complete validated VAX scale about report willingness receive reasons hesitancy. group 184 who completed survey recorded significantly more hesitant respondents than non-pregnant 161 (52.2% vs. 40.3%). They had higher average scores all subsections, while 78.1% them gave credits social media decision, compared 63.0% independent risk determined not being afraid OR = 1.89, below-average income 2.06, trusting rumors 2.38, believing existence 2.67, non-believer 3.15. We advocate get vaccinated against development targeted campaigns address hesitation. This emphasizes need delivering whole community, including may have vaccine-related concerns.
Язык: Английский
Процитировано
44
Obstetrics & Gynecology Science, Год журнала: 2023, Номер 66(4), С. 270 - 289
Опубликована: Май 17, 2023
The coronavirus disease 2019 (COVID-19) outbreak which started in December rapidly developed into a global health concern. Pregnant women are susceptible to respiratory infections and can experience adverse outcomes. This systematic review meta-analysis compared pregnancy outcomes according COVID-19 status. MEDLINE, EMBASE, Cochrane Library databases were searched for relevant articles published between 1, 2019, October 19, 2022. Main inclusion criterion was any population-based, cross-sectional, cohort, or case-control study that assessed with without laboratory-confirmed COVID-19. Sixty-nine studies including 1,606,543 pregnant (39,716 [2.4%] diagnosed COVID-19) retrieved. COVID-19-infected had higher risk of preterm birth (odds ratio [OR], 1.59; 95% confidence interval [CI], 1.42-1.78), preeclampsia (OR, 1.41; CI, 1.30-1.53), low weight 1.52; 1.30-1.79), cesarean delivery 1.20; 1.10-1.30), stillbirth 1.71; 1.39-2.10), fetal distress 2.49; 1.54-4.03), neonatal intensive care unit admission 2.33; 1.72-3.16), perinatal mortality 1.96; 1.15-3.34), maternal 6.15; 3.74-10.10). There no significant differences total miscarriage, premature rupture membranes, postpartum hemorrhage, cholestasis, chorioamnionitis infection. demonstrates infection during lead information could aid researchers clinicians preparing another pandemic caused by newly discovered viruses. findings this may assist evidence-based counseling help manage
Язык: Английский
Процитировано
15
Scientific Reports, Год журнала: 2024, Номер 14(1)
Опубликована: Фев. 11, 2024
Abstract To quantify transplacental transmission of SARS-CoV-2 virus and antibody transfer in pregnant women their newborns according to the gestational age at maternal infection. A prospective observational multicenter study including with a positive RT-PCR or serology for compatible symptoms, from April December 2020, 11 French maternities. The was designed obtain systematic collection mother-infant dyad’s samples birth. viral load measured by RT-PCR. IgG IgM antibodies against spike protein were enzyme-linked immunosorbent assay. Antibody concentrations ratios analyzed primary outcome rate SARS CoV-2 materno-fetal secondary quantification transfer. Maternal neonatal outcomes birth additionally assessed. Among 165 dyads enrolled, one congenital infection confirmed {n = 1 (0.63%) IC 95% [0.02%; 3.48%]}. average placental ratio 1.27 (IC [0.69–2.89]). increased increasing time between onset delivery ( P Value 0.0001). reassuring. We very low (< 1%). fetus more efficient when occurred during first second trimester pregnancy.
Язык: Английский
Процитировано
5
Cureus, Год журнала: 2024, Номер unknown
Опубликована: Фев. 16, 2024
In this systematic review and meta-analysis, we aimed to the characteristics outcomes of newborns Coronavirus disease 2019 (COVID-19) infected pregnant women. We conducted an online bibliographic search using following electronic databases: MEDLINE via PubMed, Scopus, Web Science, Cochrane Central. Studies were deemed eligible if they recruited from mothers with confirmed COVID-19 reported perinatal neonatal cases. A total 20 studies included. Neonates born positive results have been shown significantly lower birth weights (mean difference, MD = -48.54 g, p 0.04), increased risks fetal distress (odds ratio, OR 1.76, < 0.00001), respiratory (OR 1.96, 0.006), premature 2.08, death 2.20, 0.004), a 5-minute Apgar score 1.44, 0.02). Additionally, more likely be admitted intensive care unit (NICU) 2.25, 0.007) test for themselves 9.88, 0.03). However, other parameters, such as malformations, mechanical ventilation, hypoglycemia, sepsis, appeared comparable between two groups. Maternal infection during pregnancy is associated several outcomes, some which are adverse others that do not show significant deviation norms. While our meta-analysis clearly illustrates heightened birth, reduced weight, challenges, it also emphasizes all can directly attributed maternal SARS-CoV-2 infection.
Язык: Английский
Процитировано
5
The Journal of Maternal-Fetal & Neonatal Medicine, Год журнала: 2022, Номер 35(25), С. 9368 - 9375
Опубликована: Фев. 13, 2022
Background: The Coronavirus disease 2019 (COVID-19) pandemic has become worldwide, posing particularly severe challenges. Pregnancy brings changes that might make individuals more vulnerable to this viral infection. To date, the impact of COVID-19 infection on pregnancy outcomes remains controversial.Method: We performed a meta-analysis address outcomes. searched PubMed and China National Knowledge infrastructure (CNKI) databases for related articles. odds ratio (OR) corresponding 95% confidence interval (95% CI) was used define INFECTION severity statistical heterogeneity among studies batched with Q-test I2 statistics.Results: collected 38 including 127,805 women. Our revealed pregnant women have been linked an increased risk premature birth (OR = 1.66, CI 1.41–1.96), stillbirth 1.98, 1.22–3.21), pre-eclampsia 1.46, 1.18–1.80), PROM 1.39, 1.07–1.81).Conclusions: showed increases preterm birth, stillbirth, pre-eclampsia, PROM. Screening early care intervene is important, given adverse
Язык: Английский
Процитировано
22
Frontiers in Public Health, Год журнала: 2022, Номер 10
Опубликована: Июль 19, 2022
Vaccination is the best means of reducing increased risk severe COVID-19 during pregnancy. Data on vaccine uptake among pregnant women in Ethiopia scarce. Thus, this study aimed to assess and associated factors women.An institution-based cross-sectional was conducted 634 attending antenatal care Debre Tabor public health institutions from March 14 30, 2022. Participants were recruited using a multistage sampling technique data collected via face-to-face interviews pre-tested structured questionnaire. Stata version 16.0 software used for analysis. Multiple logistic regression analysis with uptake, p-value< 0.05 considered statistically significant.Only 14.4% (95% CI: 11.7%-17.3%) participants had received at least one dose vaccines. The main reasons declining vaccination fear that may have harmful side effects fetus or mother. Being 45 older (AOR: 1.75, 95%CI: 1.01-2.95), being married 1.26, 1.12, 2.96), having good knowledge (AOR:3.52, 95%CI:1.83-3.87), positive attitude (AOR:4.81, 95% 1.42-7.33) predictors uptake. But attaining college university education 0.43, 0.12-0.69) found be barrier by women.COVID-19 substantially low. Old age, married, low education, knowledge, significant To enhance government should improve toward vaccine.
Язык: Английский
Процитировано
22
Nutrients, Год журнала: 2022, Номер 14(4), С. 836 - 836
Опубликована: Фев. 16, 2022
Anemia is a very common occurrence during pregnancy, with important variations each trimester. was also considered as risk factor for severity and negative outcomes in patients SARS-CoV-2 infection. As the COVID-19 pandemic poses significant threat pregnant women terms of infection access to care, we developed study determine impact nutritional supplementation iron deficiency anemia correlation status In case-control design, identified 446 pregnancies that matched our inclusion criteria from hospital database. The cases controls were stratified by history observe association between exposure both mother newborn. A total 95 diagnosed COVID-19, having significantly higher proportion anemia. Low birth weight, prematurity, lower APGAR scores statistically more often occurring group. Birth weight showed wide variation pregnancy. daily combination folate optimal choice normalize at birth. complete blood count laboratory studies decreased levels exposure. Puerperal infection, emergency c-section, small gestational age strongly associated COVID-19. It imperative screen complications, it recommended supplement intake these two promote normal development growth newborn avoid multiple complications pregnancy setting.
Язык: Английский
Процитировано
19
Reproductive Female and Child Health, Год журнала: 2025, Номер 4(2)
Опубликована: Апрель 6, 2025
ABSTRACT Objective To evaluate COVID‐19 infection during pregnancy as a risk factor for preterm labour. Methods Following institutional review board approval, single‐institution retrospective chart was conducted on 2760 patients, with 2397 meeting inclusion criteria. Pregnant women delivering after 20 weeks between 1 March 2020 and 31 December 2021 were included. Exclusion criteria included no documented COVID test, multifetal gestations, deliveries under or delivery at another institution. The primary outcome labour incidence among those COVID‐19, assessed by gestational age delivery. Statistical analyses chi‐squared tests, Fisher's exact tests two‐sample t ‐tests significance set p < 0.05. study had 80% power. Results Of 200 COVID‐positive, 2197 COVID‐negative. Preterm occurred in 12.0% of COVID‐positive cases versus 10.3% COVID‐negative ( = 0.523, RR 1.17, 95% CI 0.79–1.73), significant differences demographics other clinical factors groups. After adjusting patient (age, race parity) variables (gestational delivery, BMI, tobacco use, recreational drug pregestational diabetes, chronic hypertension, current diagnosis hypertensive disorders including pre‐eclampsia without severe features, STIs, PPROM, history prior pregnancies), not associated increased 0.532). Conclusion significantly These results help guide physician counselling address concerns regarding risks pregnancy.
Язык: Английский
Процитировано
0
Journal of Personalized Medicine, Год журнала: 2023, Номер 13(2), С. 195 - 195
Опубликована: Янв. 21, 2023
The Roma population accounts for over 3% (approximately 10 to 15 million) of Romania's permanent population, and it represents one Europe's most impoverished populations. Due poverty unemployment, minority may have diminished access healthcare preventive medicine. limited existing evidence suggests that the European group has been at a higher risk becoming ill dying during pandemic owing their lifestyle choices, socioeconomic circumstances, genetic pathophysiological traits. As result, purpose present research was investigate link between inflammatory markers implicated clinical progression COVID-19 in patients who were brought intensive care unit. We considered 71 admitted ICU with SARS-CoV-2 infection 213 controls from general same inclusion criteria. body mass index statistically significantly among patients, more than 57% being overweight, compared 40.7% control group. Frequent smoking prevalent ethnicity number comorbidities. observed proportion severe imaging features admission cases, although this difference associated prevalence mean duration hospitalization longer by 1.8 days Elevated ESR levels 54.0% admission, 38.9% Similarly, 47.6% them had elevated CRP levels. IL-6 increased time similarly significant rise levels, population. However, intubated mortality did not differ significantly. On multivariate analysis, influenced (β = 1.93, p-value 0.020) 1.85, 0.044). It is necessary plan different strategies aimed special populations, such as ethnicity, prevent reduced disparities presented study.
Язык: Английский
Процитировано
9