Dietary Acculturation Is Associated With Altered Gut Microbiome, Circulating Metabolites, and Cardiovascular Disease Risk in US Hispanics and Latinos: Results From HCHS/SOL

Circulation, Год журнала: 2024, Номер 150(3), С. 215 - 229

Опубликована: Июнь 19, 2024

Dietary acculturation, or adoption of dominant culture diet by migrant groups, influences human health. We aimed to examine dietary acculturation and its relationships with cardiovascular disease (CVD), gut microbiota, blood metabolites among US Hispanic Latino adults.

Язык: Английский

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Does “all disease begin in the gut”? The gut-organ cross talk in the microbiome

Applied Microbiology and Biotechnology, Год журнала: 2024, Номер 108(1)

Опубликована: Май 21, 2024

Abstract The human microbiome, a diverse ecosystem of microorganisms within the body, plays pivotal roles in health and disease. This review explores site-specific microbiomes, their role maintaining health, strategies for upkeep, focusing on oral, lung, vaginal, skin, gut microbiota, systemic connections. Understanding intricate relationships between these microbial communities is crucial unraveling mechanisms underlying health. Recent research highlights bidirectional communication distant microbiome sites, influencing immune function, metabolism, disease susceptibility. Alterations one can impact others, emphasizing interconnectedness collective influence physiology. therapeutic potential microbiota modulating microbiomes offers promising avenues interventions targeting various disorders. Through interdisciplinary collaboration technological advancements, we harness power to revolutionize healthcare, microbiome-centric approaches promote holistic well-being while identifying areas future research.

Язык: Английский

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An Anti-Inflammatory Diet and Its Potential Benefit for Individuals with Mental Disorders and Neurodegenerative Diseases—A Narrative Review

Nutrients, Год журнала: 2024, Номер 16(16), С. 2646 - 2646

Опубликована: Авг. 10, 2024

This narrative review synthesizes current evidence regarding anti-inflammatory dietary patterns and their potential benefits for individuals with mental disorders neurodegenerative diseases. Chronic low-grade inflammation is increasingly recognized as a key factor in the etiology progression of these conditions. The examines neuroprotective properties components food groups, focusing on whole foods rather than specific nutrients or supplements. Key showing include fruits vegetables (especially berries leafy greens), grains, legumes, fatty fish rich omega-3, nuts (particularly walnuts), olive oil, fermented foods. These are generally antioxidants, fiber, bioactive compounds that may help modulate inflammation, support gut health, promote neuroprotection. Conversely, ultra-processed foods, red meat, sugary beverages be harmful. Based this evidence, we designed Brain Anti-Inflammatory Nutrition (BrAIN) diet. mechanisms diet modulation microbiota gut-brain axis, regulation inflammatory pathways, reduction oxidative stress, promotion neuroplasticity. BrAIN shows promise an aid to manage disorders.

Язык: Английский

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Diet and Nutraceuticals for treatment and prevention of primary and secondary stroke: emphasis on nutritional antiplatelet and antithrombotic agents

Neurochemistry International, Год журнала: 2024, Номер 179, С. 105823 - 105823

Опубликована: Июль 30, 2024

Язык: Английский

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Sleep apnoea, gut dysbiosis and cognitive dysfunction

FEBS Journal, Год журнала: 2023, Номер 291(12), С. 2519 - 2544

Опубликована: Сен. 15, 2023

Sleep disorders are becoming increasingly common, and their distinct effects on physical mental health require elaborate investigation. Gut dysbiosis (GD) has been reported in sleep-related disorders, but sleep apnoea is of particular significance because its higher prevalence chronicity. Cumulative evidence suggested a link between GD. This review highlights the gut-brain communication axis that mediated via commensal microbes various microbiota-derived metabolites (e.g. short-chain fatty acids, lipopolysaccharide trimethyl amine N-oxide), neurotransmitters γ-aminobutyric acid, serotonin, glutamate dopamine), immune cells inflammatory mediators, as well vagus nerve hypothalamic-pituitary-adrenal axis. also discusses pathological role underpinning GD altered gut bacterial populations related comorbid conditions, particularly cognitive dysfunction. In addition, examines preclinical clinical evidence, which suggests prebiotics probiotics may potentially be beneficial comorbidities through restoration eubiosis or microbial homeostasis regulates neural, metabolic responses, physiological barrier integrity

Язык: Английский

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A Randomized, Double-Blind, Placebo-Controlled Trial: Efficacy of Opuntia ficus-indica Prebiotic Supplementation in Subjects with Gut Dysbiosis

Nutrients, Год журнала: 2024, Номер 16(5), С. 586 - 586

Опубликована: Фев. 21, 2024

Gut dysbiosis refers to an imbalance in gut microbiota composition and function.

Язык: Английский

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Short-term dietary fiber interventions produce consistent gut microbiome responses across studies

mSystems, Год журнала: 2024, Номер 9(6)

Опубликована: Май 14, 2024

The composition of the human gut microbiome varies tremendously among individuals, making effects dietary or treatment interventions difficult to detect and characterize. consumption fiber is important for health, yet specific increased intake on vary across studies. variation in study outcomes might be due inter-individual (or inter-population) details including types fiber, length study, size cohort, molecular approaches. Thus, identify generally (on average) consistent fiber-induced responses healthy we re-analyzed 16S rRNA sequencing data from 21 12 studies, which included 2,564 fecal samples 538 subjects all interventions. Short-term increases resulted highly bacterial community Increased explained an average 1.5% compositional (vs 82% attributed individual), reduced alpha-diversity, phylogenetically conserved relative abundances taxa. Additionally, identified clades, at approximately genus level, that were their response average, increasing decreasing abundance)

Язык: Английский

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Nutrition Intervention and Microbiome Modulation in the Management of Breast Cancer

Nutrients, Год журнала: 2024, Номер 16(16), С. 2644 - 2644

Опубликована: Авг. 10, 2024

Breast cancer (BC) is one of the most common cancers worldwide and a leading cause cancer-related deaths among women. The escalating incidence BC underscores necessity multi-level treatment. complex heterogeneous disease involving many genetic, lifestyle, environmental factors. Growing evidence suggests that nutrition intervention an evolving effective prevention treatment strategy for BC. In addition, human microbiota, particularly gut now widely recognized as significant player contributing to health or status. It also associated with risk development This review will focus on in BC, including dietary patterns, bioactive compounds, nutrients affect therapeutic responses both animal studies. Additionally, this paper examines impacts these interventions modulating composition functionality microbiome, highlighting microbiome-mediated mechanisms combination factors microbes discussed. Insights from emphasize comprehensive management focuses nutrition–microbiome axis.

Язык: Английский

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Probiotics and the Role of Dietary Substrates in Maintaining the Gut Health: Use of Live Microbes and Their Products for Anticancer Effects against Colorectal Cancer

Journal of Microbiology and Biotechnology, Год журнала: 2024, Номер 34(10), С. 1933 - 1946

Опубликована: Авг. 8, 2024

Язык: Английский

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Identification of gut microbiome features associated with host metabolic health in a large population-based cohort

Nature Communications, Год журнала: 2024, Номер 15(1)

Опубликована: Окт. 29, 2024

Язык: Английский

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