Lacticaseibacillus rhamnosus: An Overview of the Viability in Fruit and Vegetable Juices and Their Potential Effects on Human Health
Probiotics and Antimicrobial Proteins,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 4, 2025
Язык: Английский
Impact of probiotics-derived extracellular vesicles on livestock gut barrier function
Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology,
Год журнала:
2024,
Номер
15(1)
Опубликована: Ноя. 7, 2024
Abstract
Probiotic
extracellular
vesicles
(pEVs)
are
biologically
active
nanoparticle
structures
that
can
regulate
the
intestinal
tract
through
direct
or
indirect
mechanisms.
They
enhance
barrier
function
in
livestock
and
poultry
help
alleviate
diseases.
The
specific
effects
of
pEVs
depend
on
their
internal
functional
components,
including
nucleic
acids,
proteins,
lipids,
other
substances.
This
paper
presents
a
narrative
review
impact
across
various
segments
tract,
exploring
mechanisms
action
while
highlighting
limitations
current
research.
Investigating
which
probiotics
operate
via
could
deepen
our
understanding
provide
theoretical
foundation
for
application
production.
Язык: Английский
Lactobacillus rhamnosus GG Ameliorates Atherosclerosis via Suppression of Oxidative Stress and Inflammation by Reshaping the Gut Microbiota
Biochemical and Biophysical Research Communications,
Год журнала:
2025,
Номер
751, С. 151417 - 151417
Опубликована: Фев. 5, 2025
Язык: Английский
Microbiota modulation for infectious complications following allogeneic hematopoietic stem cell transplantation in pediatric hematological malignancies
Frontiers in Pediatrics,
Год журнала:
2025,
Номер
13
Опубликована: Март 14, 2025
The
intervention
of
microbiota
modulation
in
the
treatment
infection
complications
after
allogeneic
hematopoietic
stem
cell
transplantation
pediatric
patients
with
hematological
malignancies
has
shown
potential
benefits.
Through
use
probiotics,
prebiotics,
synbiotics,
and
fecal
(FMT),
these
interventions
modulate
gut
enhance
immune
function
to
prevent
treat
infections.
They
have
been
reduce
incidence
diarrhea
intestinal
infections,
mitigate
issue
antibiotic
resistance,
promote
recovery
microbiota.
Future
research
is
needed
further
assess
safety
efficacy
establish
standardized
protocols.
Язык: Английский
Anti-inflammatory effect of Lactiplantibacillus plantarum strains through MAPK, NF-κB, and AP-1 signaling pathways and its application in soy milk
Food Research International,
Год журнала:
2025,
Номер
208, С. 116216 - 116216
Опубликована: Март 17, 2025
Язык: Английский
LGG promotes activation of intestinal ILC3 through TLR2 receptor and inhibits salmonella typhimurium infection in mice
Virulence,
Год журнала:
2024,
Номер
15(1)
Опубликована: Июль 30, 2024
Salmonella
is
a
foodborne
pathogen
that
causes
disruption
of
intestinal
mucosal
immunity,
leading
to
acute
gastroenteritis
in
the
host.
In
this
study,
we
found
Typhimurium
(STM)
infection
tract
mice
led
significant
increase
proportion
Lacticaseibacillus,
while
secretion
IL-22
from
type
3
innate
lymphoid
cells
(ILC3)
increased
significantly.
Feeding
Lacticaseibacillus
rhamnosus
GG
(LGG)
effectively
alleviated
STM
mouse
intestines.
TLR2−/−
experiments
TLR2-expressing
dendritic
(DCs)
are
crucial
for
LGG's
activation
ILC3.
Subsequent
vitro
showed
heat-killed
LGG
(HK-LGG)
could
promote
DCs
secrete
IL-23,
which
turn
further
promotes
ILC3
and
IL-22.
Finally,
organoid
verified
secreted
by
can
enhance
immune
barrier
inhibit
infection.
This
study
demonstrates
oral
administration
potential
method
inhibiting
Язык: Английский
Chairside live biotherapeutic hydrogel for comprehensive periodontitis therapy
Trends in biotechnology,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 1, 2024
Язык: Английский
Akkermansia muciniphila: new insights into resistance to gastrointestinal stress, adhesion, and protein interaction with human mucins through optimised in vitro trials and bioinformatics tools
Frontiers in Microbiology,
Год журнала:
2024,
Номер
15
Опубликована: Ноя. 5, 2024
According
to
the
FAO/WHO
guidelines,
selection
of
probiotics
requires
assessment
survival
under
gastrointestinal
stress
and
adhesion
human
epithelial
cells.
These
attributes
were
evaluated
on
Akkermansia
muciniphila
ATCC
BAA-835
simulating
transit
(GIT)
immediately
followed
by
intestinal
cell
lines
(CaCo2,
HT-29,
HT-29-MTX)
as
an
alternative
approach
in
vitro
methods
performed
with
fresh
cells
each
trial.
The
rate
after
GIT,
determined
plate
counts
fluorescent
probes,
was
significantly
higher
for
A.
(about
8
Log
CFU/mL)
than
probiotic
Lacticaseibacillus
rhamnosus
GG
53103
3
CFU/mL).
use
Live/Dead
assay
highlighted
that
forms
aggregates
gastric
phase
protective
mechanism,
explaining
its
high
viability
intestine.
always
lower
strains
tested
simulated
GIT
did
not
undergo
GIT.
exhibited
Lbs.
GG,
particularly
mucus-secreting
HT-29-MTX
across
a
range
concentrations
(2–8
Finally,
bioinformatic
analysis
proteome
confirmed
Amuc_1434
potential
factor
binding
MUC2
protein.
Язык: Английский
Lactobacillus rhamnosus: An Emerging Probiotic with Therapeutic Potential for Depression
Pharmacological Research,
Год журнала:
2024,
Номер
unknown, С. 107541 - 107541
Опубликована: Дек. 1, 2024
Depression,
a
complex
psychological
disorder,
involves
multiple
biological
pathways
in
its
pathogenesis.
In
recent
years,
the
gut-brain
axis
theory
has
provided
novel
insights
into
pathogenesis
of
depression,
particularly
crucial
role
gut
microbiota
mood
regulation.
While
there
remains
no
universal
consensus
on
most
efficacious
strains
for
depression
treatment,
Lactobacillus
rhamnosus
risen
to
prominence
within
realm
probiotics
potential
positively
modulate
depressive
symptoms.
This
review
preliminarily
explores
clinical
significance
treatment
and
summarizes
mechanisms
by
which
treats
including
regulation
microbiota,
alterations
gene
expression,
improvement
intestinal
barrier
function,
maintenance
neurotransmitter
balance,
suppression
inflammatory
responses,
modulation
immune
system,
coping
with
oxidative
stress,
optimization
metabolic
processes.
Future
research
needs
further
explore
these
combine
them
results
optimize
plans
provide
more
effective
options
patients
depression.
Язык: Английский
Сomparative characteristics of cytokine profile induced in vitro by supernatants of industrial and intestinal strains of bifido- and lactobacteria
Medical Immunology (Russia),
Год журнала:
2024,
Номер
27(2), С. 437 - 444
Опубликована: Окт. 4, 2024
The
immunomodulatory
properties
of
probiotics
largely
depend
on
the
metabolites
secreted
into
culture
medium,
which
is
studied
as
a
cell-free
supernatant
and
referred
to
postbiotics.
aim
present
work
was
conduct
screening
cytokine
profiles
for
intestinal
strains
Bifidobacteria
Lactobacillus
by
testing
it
with
mononuclear
cells
from
human
peripheral
blood,
comparing
profile
typical
industrial
bacterial
strains,
in
order
select
promising
anti-inflammatory
potential
pro-/postbiotics.
probiotic
isolated
large
intestine
healthy
people
determined
biological
effects
supernatants
production
pro-
(IFNγ,
TNFα,
IL-17,
IL-8,
IL-6)
(IL-10,
IL-1ra)
cytokines
vitro
model
blood.
We
have
established
three
types
profile:
type
1
characterized
predominant
increase
IL-10
production,
decrease
IL-6;
2,
produced
decrease,
mainly
at
level
pro-inflammatory
cytokines;
3
caused
decreased
secretion
both
cytokines.
Among
2
cultures,
Bifidobacterium
bifidum
ICIS-202
ICIS-504
had
high
potential,
capable
suppressing
cytokines,
enhancing
L.
ruminis
ICIS-540
strain
showed
effect,
i.e.,
repeatedly
reduced
early
proinflammatory
TNFα
cytokine.
activity
these
not
inferior,
but,
relation
individual
IL-6),
superior
known
cultures.
metabolic
products
enabled
us
ICIS-540,
B.
may
be
suitable
implementation
preparations
activity.
Язык: Английский