Antimicrobial Actions and Applications of Chitosan

Polymers, Год журнала: 2021, Номер 13(6), С. 904 - 904

Опубликована: Март 15, 2021

Chitosan is a naturally originating product that can be applied in many areas due to its biocompatibility, biodegradability, and nontoxic properties. The broad-spectrum antimicrobial activity of chitosan offers great commercial potential for this product. Nevertheless, the varies, because associated with physicochemical characteristics depends on type microorganism. In review article, fundamental properties, modes action, effects-related factors are discussed. We further summarize how microorganisms genetically respond chitosan. Finally, applications chitosan-based biomaterials, such as nanoparticles films, combination current clinical antibiotics or antifungal drugs, also addressed.

Язык: Английский

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Biopolymer: A Sustainable Material for Food and Medical Applications

Polymers, Год журнала: 2022, Номер 14(5), С. 983 - 983

Опубликована: Фев. 28, 2022

Biopolymers are a leading class of functional material suitable for high-value applications and great interest to researchers professionals across various disciplines. Interdisciplinary research is important understand the basic applied aspects biopolymers address several complex problems associated with good health well-being. To reduce environmental impact dependence on fossil fuels, lot effort has gone into replacing synthetic polymers biodegradable materials, especially those derived from natural resources. In this regard, many types or have been developed meet needs ever-expanding applications. These currently used in food expanding their use pharmaceutical medical industries due unique properties. This review focuses uses industry provides future outlook biopolymer industry.

Язык: Английский

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Chitin and chitin-based biomaterials: A review of advances in processing and food applications

Carbohydrate Polymers, Год журнала: 2022, Номер 299, С. 120142 - 120142

Опубликована: Сен. 22, 2022

Язык: Английский

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Chitin, Chitosan, and Nanochitin: Extraction, Synthesis, and Applications

Polymers, Год журнала: 2022, Номер 14(19), С. 3989 - 3989

Опубликована: Сен. 23, 2022

Crustacean shells are a sustainable source of chitin. Extracting chitin from crustacean is ongoing research, much which devoted to devising process that yields high-quality with minimal waste. Chemical and biological methods have been used extensively for this purpose; more recently, based on ionic liquids deep eutectic solvents explored. Extracted can be converted into chitosan or nanochitin. Once obtained modified the desired form, it in wide array applications, including as filler material, adsorbents, component biomaterials, among others. Describing extraction chitin, synthesis nanochitin, applications these materials aim review. The first section review summarizes compares common methods, highlighting benefits shortcomings each, followed by descriptions convert second discusses some range its derivatives.

Язык: Английский

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Chitosan-based nanostructured biomaterials: Synthesis, properties, and biomedical applications

Advanced Industrial and Engineering Polymer Research, Год журнала: 2023, Номер 7(1), С. 79 - 99

Опубликована: Июль 19, 2023

Chitosan is obtained from chitin, which abundantly found in crustaceans and through various methods. The demineralization, deproteinization, discoloration, deacetylation of chitin produce chitosan consisting D-glucosamine N-acetyl units that are linked β-(1,4)-glycosidic linkages. has gained significant attention the biomedical field due to its unique properties such as abundance, renewability, non-toxic nature, antimicrobial activity, biodegradability, polyfunctionality. One key why it been heavily utilized field. To provide a comprehensive overview chitosan, this review discusses extraction based on source It also delves into chemical modifications nanocomposite development using natural synthetic materials. emphasizes multitude make an excellent choice for wide range applications. mechanisms antibacterial activity factors affecting activity. Additionally, highlights hemocompatibility, antioxidant anti-inflammation, other contribute suitability different applications, including wound dressing materials, drug delivery carriers, biosensing diagnostic devices, bone substitutes, bioimaging. While discussing some limitations concludes with future perspective developing multifunctional chitosan-based nanomaterials could potentially move laboratory clinical trials treating diseases.

Язык: Английский

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Progress in chitin/chitosan and their derivatives for biomedical applications: Where we stand

Carbohydrate Polymers, Год журнала: 2024, Номер 343, С. 122233 - 122233

Опубликована: Май 4, 2024

Язык: Английский

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Ultramodern natural and synthetic polymer hydrogel scaffolds for articular cartilage repair and regeneration

BioMedical Engineering OnLine, Год журнала: 2025, Номер 24(1)

Опубликована: Фев. 7, 2025

Articular cartilage injury is a serious bone disease that can result in disabilities. With the rapid increase aging population, this disorder has become an increasingly important public health issue. Recently, stem cell-based tissue engineering emerged as promising therapeutic option for treating articular damage. Cellular scaffolds, which are among three key elements of engineering, play significant roles repair damaged by regulating cellular responses and promoting regeneration. Biological macromolecules commonly used scaffold materials owing to their unique properties. For example, natural synthetic polymer hydrogel scaffolds effectively mimic microenvironment extracellular matrix; exhibit high cytocompatibility, biocompatibility, biodegradability; have attracted increasing attention regeneration medicine. Several types been fabricated treat abnormalities. This article outlines recent progress field manufactured from various biomaterials repairing cartilage, discusses advantages disadvantages, proposes directions future development.

Язык: Английский

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Chitosan-Based Scaffold for Mineralized Tissues Regeneration

Marine Drugs, Год журнала: 2021, Номер 19(10), С. 551 - 551

Опубликована: Сен. 28, 2021

Conventional bone grafting procedures used to treat defects have several limitations. An important aspect of tissue engineering is developing novel substitute biomaterials for grafts repair orthopedic defects. Considerable attention has been given chitosan, a natural biopolymer primarily extracted from crustacean shells, which offers desirable characteristics, such as being biocompatible, biodegradable, and osteoconductive. This review presents an overview the chitosan-based (BTE). It covers basic knowledge chitosan in terms biomaterials, traditional strategies scaffold fabrication process, their advantages disadvantages. Furthermore, this paper integrates relevant contributions giving brief insight into recent research development scaffolds limitations BTE. The last part discusses next-generation smart current applications regenerative dentistry future directions field mineralized regeneration.

Язык: Английский

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Chitosan and Chitooligosaccharide: The Promising Non-Plant-Derived Prebiotics with Multiple Biological Activities

International Journal of Molecular Sciences, Год журнала: 2022, Номер 23(12), С. 6761 - 6761

Опубликована: Июнь 17, 2022

Biodegradable chitin is the second-most abundant natural polysaccharide, widely existing in exoskeletons of crabs, shrimps, insects, and cell walls fungi. Chitosan chitooligosaccharide (COS, also named chitosan oligosaccharide) are two most important deacetylated derivatives chitin. Compared with chitin, COS not only have more satisfactory physicochemical properties but exhibit additional biological activities, which cause them to be applied fields food, medicine, agriculture. Additionally, due their significant ability improve gut microbiota, deemed prospective prebiotics. Here, we introduced production, properties, applications, pharmacokinetic characteristics COS. Furthermore, summarized latest research on antioxidant, anti-inflammatory, antimicrobial activities. Research progress prebiotic functions particularly reviewed. We creatively analyzed discussed mechanisms correlations underlying these activities properties. Our work enriched people's understanding non-plant-derived Based this review, future directions explored. Collectively, optimizing production technology enriching will shed light capability human health.

Язык: Английский

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A Review in Investigation of Marine Biopolymer (Chitosan) for Bioapplications

ES Materials & Manufacturing, Год журнала: 2023, Номер unknown

Опубликована: Янв. 1, 2023

Recent studies have used more marine-origin polysaccharides since they are widely available, economical, biocompatible, and biodegradable.These characteristics promote their technological use in water treatment, tissue engineering, cancer therapy, wound dressing, drug delivery systems, biosensors.Due to its versatility capacity be produced from waste marine crustaceans, chitosan is becoming important a range of fields.It first utilized biomedical applications due versatile properties, which include biocompatibility, antibacterial activity, biodegradability.A summary (chitosan), including supply, chemical, biological characteristics, uses given this review.

Язык: Английский

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