The Microalgae Chlamydomonas for Bioremediation and Bioproduct Production DOI Creative Commons
Carmen M. Bellido-Pedraza, María J. Torres, Ángel Llamas

и другие.

Cells, Год журнала: 2024, Номер 13(13), С. 1137 - 1137

Опубликована: Июль 2, 2024

The extensive metabolic diversity of microalgae, coupled with their rapid growth rates and cost-effective production, position these organisms as highly promising resources for a wide range biotechnological applications. These characteristics allow microalgae to address crucial needs in the agricultural, medical, industrial sectors. Microalgae are proving be valuable various fields, including remediation diverse wastewater types, production biofuels biofertilizers, extraction products from biomass. For decades, microalga

Язык: Английский

Natural Compounds and Products from an Anti-Aging Perspective DOI Creative Commons
Geir Bjørklund, Mariia Shanaida, Roman Lysiuk

и другие.

Molecules, Год журнала: 2022, Номер 27(20), С. 7084 - 7084

Опубликована: Окт. 20, 2022

Aging is a very complex process that accompanied by degenerative impairment in many of the major functions human body over time. This inevitable influenced hereditary factors, lifestyle, and environmental influences such as xenobiotic pollution, infectious agents, UV radiation, diet-borne toxins, so on. Many external internal signs symptoms are related with aging senescence, including skin dryness wrinkles, atherosclerosis, diabetes, neurodegenerative disorders, cancer, etc. Oxidative stress, consequence imbalance between pro- antioxidants, one main provoking factors causing aging-related damages concerns, due to generation highly reactive byproducts oxygen nitrogen species during metabolism, which result cellular damage apoptosis. Antioxidants can prevent these processes extend healthy longevity ability inhibit formation free radicals or interrupt their propagation, thereby lowering level oxidative stress. review focuses on supporting antioxidant system organism balancing diet through consumption necessary amount natural ingredients, vitamins, minerals, polyunsaturated fatty acids (PUFA), essential amino acids, probiotics, plants’ fibers, nutritional supplements, polyphenols, some phytoextracts, drinking water.

Язык: Английский

Процитировано

111

The Biochemistry and Effectiveness of Antioxidants in Food, Fruits, and Marine Algae DOI Creative Commons
Lavinia-Lorena Pruteanu, David Bailey, A. C. Grădinaru

и другие.

Antioxidants, Год журнала: 2023, Номер 12(4), С. 860 - 860

Опубликована: Апрель 2, 2023

It is more effective to maintain good health than regain it after losing it. This work focuses on the biochemical defense mechanisms against free radicals and their role in building maintaining antioxidant shields, aiming show how balance, as much possible, situations which we are exposed radicals. To achieve this aim, foods, fruits, marine algae with a high content should constitute basis of nutritional elements, since natural products known have significantly greater assimilation efficiency. review also gives perspective use antioxidants can extend life food products, by protecting them from damage caused oxidation well additives.

Язык: Английский

Процитировано

56

Skin Protection by Carotenoid Pigments DOI Open Access
Jolanta Flieger, Magdalena Raszewska-Famielec, Elżbieta Radzikowska-Büchner

и другие.

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(3), С. 1431 - 1431

Опубликована: Янв. 24, 2024

Sunlight, despite its benefits, can pose a threat to the skin, which is natural protective barrier. Phototoxicity caused by overexposure, especially ultraviolet radiation (UVR), results in burns, accelerates photoaging, and causes skin cancer formation. Natural substances of plant origin, i.e., polyphenols, flavonoids, photosynthetic pigments, protect against effects radiation, acting not only as photoprotectors like filters but antioxidant anti-inflammatory remedies, alleviating photodamage skin. Plant-based formulations are gaining popularity an attractive alternative synthetic filters. Over past 20 years, large number studies have been published assess photoprotective products, primarily through their antioxidant, antimutagenic, anti-immunosuppressive activities. This review selects most important data on efficacy selected carotenoid representatives from vivo animal models humans, well vitro experiments performed fibroblast keratinocyte cell lines. Recent research carotenoids associated with lipid nanoparticles, nanoemulsions, liposomes, micelles reviewed. The focus was collecting those nanomaterials that serve improve bioavailability stability antioxidants activity.

Язык: Английский

Процитировано

25

Unveiling astaxanthin: biotechnological advances, delivery systems and versatile applications in nutraceuticals and cosmetics DOI

Sai Manojna Polamraju,

Janani Manochkumar,

Madhubala Ganeshbabu

и другие.

Archives of Microbiology, Год журнала: 2025, Номер 207(2)

Опубликована: Янв. 27, 2025

Язык: Английский

Процитировано

1

Application of photosensitive microalgae in targeted tumor therapy DOI
Ruoxi Wang,

Zhouyue Wang,

Min Zhang

и другие.

Advanced Drug Delivery Reviews, Год журнала: 2025, Номер unknown, С. 115519 - 115519

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

1

Characterization of microalgal β-carotene and astaxanthin: exploring their health-promoting properties under the effect of salinity and light intensity DOI Creative Commons
Aditi Sharma, Rupesh Bhardwaj,

Ankush Yadav

и другие.

Biotechnology for Biofuels and Bioproducts, Год журнала: 2025, Номер 18(1)

Опубликована: Фев. 14, 2025

Microalgae are promising sources of valuable carotenoids like β-carotene and astaxanthin with numerous health benefits. This review summarizes recent studies on producing these in microalgae under different salinity light-intensity conditions, which key factors influencing their biosynthesis. The carotenoid biosynthesis pathways microalgae, involving the methylerythritol phosphate pathway chloroplasts, described detail. effects high light stress stimulating accumulation species Haematococcus pluvialis Chromochloris zofingiensis synergistic impact discussed. Similarly, covers how induce production Dunaliella salina other microalgae. diverse health-promoting properties β-carotene, such as antioxidant, antiinflammatory, anticancer activities, highlighted. Strategies to improve yields through environmental stresses, two-stage cultivation, genetic engineering, metabolic engineering approaches evaluated. Overall, this highlights advancements reporting microalgal capability produce level 31.5% increase productivity reaching 18.1 mg/L/day lacustris. It also explores novel biotechnological strategies, including CRISPR-Cas9, for enhancing yield.

Язык: Английский

Процитировано

1

Microalgae biomass and biomolecule quantification: Optical techniques, challenges and prospects DOI Open Access
Vimal Angela Thiviyanathan, Pin Jern Ker, Shirley Gee Hoon Tang

и другие.

Renewable and Sustainable Energy Reviews, Год журнала: 2023, Номер 189, С. 113926 - 113926

Опубликована: Окт. 27, 2023

Язык: Английский

Процитировано

19

Enhancing nutrient removal of agricultural and agro-industrial wastewater utilizing symbiotic microalgal co-cultivation systems to optimize sustainable resource recovery DOI
Manogaran Lakshmikandan, Yang Fang, Sisi Ye

и другие.

Journal of Water Process Engineering, Год журнала: 2024, Номер 63, С. 105524 - 105524

Опубликована: Май 23, 2024

Язык: Английский

Процитировано

5

Astaxanthin-loaded brain-permeable liposomes for Parkinson’s disease treatment via antioxidant and anti-inflammatory responses DOI Creative Commons

Thuy-vi Nguyen,

Shristi Khanal,

Eun-Hee Lee

и другие.

Journal of Nanobiotechnology, Год журнала: 2025, Номер 23(1)

Опубликована: Фев. 4, 2025

Parkinson's disease is a neurodegenerative disorder characterized by cardinal motor symptoms resulting from the loss of dopaminergic neurons in substantia nigra pars compacta. Although current medications may alleviate its symptoms, remains incurable. Astaxanthin an antioxidant and anti-inflammatory agent; however, high susceptibility to oxidative degradation low aqueous solubility limit therapeutic efficacy. This study aimed improve pharmaceutical properties neuroprotective effects astaxanthin for treatment using lactoferrin-conjugated astaxanthin-loaded liposomes (Lf-ASX-LPs). We successfully formulated Lf-ASX-LPs with encapsulation efficiency (97.6%) favorable physical characteristics (diameter: 109.8 ± 1.1 nm; polydispersity index: 0.18 0.01; zeta potential: - 9.5 mV). Lf-functionalized demonstrated enhanced cellular uptake permeation Transwell® study, showing 16.7-fold higher internalization SH-SY5Y cells over 24 h than those without Lf conjugation. Additionally, functionalization brain penetration ability, as biodistribution nude mice, compared LPs In vitro, reduced cell 20.1% oxygen species 30.0%, ameliorated reduction mitochondrial membrane potential under 1-methyl-4-phenylpyridinium-induced toxicity 40.1%, extracellular nitric oxide levels lipopolysaccharide-induced 32.0%, indicating cytoprotective effects. 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mouse model, resulted 5.0-, 3.1-, 5.6-fold increases dopamine levels, TH+ fiber density, neurons, respectively, restoring neuron damage. The developed formulation also alleviated behavioral impairment neuroinflammation, reducing astrocyte microglial activation striatum MPTP-treated animals. Thus, our represents promising strategy providing neuroprotection retarding progression.

Язык: Английский

Процитировано

0

Evaluation of the Quality and Antiaging Activity of Phaffia rhodozyma DOI Creative Commons
Yuan Cao, Chong Chen, Won Young Han

и другие.

Journal of Chemistry, Год журнала: 2025, Номер 2025(1)

Опубликована: Янв. 1, 2025

Phaffia rhodozyma (PR) is a candidate microbial strain for the production of natural astaxanthin. Astaxanthin and other carotenoids have significant antioxidant effects, which can delay aging prevent tumors. However, so far, there no effective convenient method to comprehensively reflect quality PR, also gap in research on potential antiaging effect PR. In this study, 15 batches PR samples collected China were analyzed using high‐performance liquid chromatography (HPLC) fingerprinting. A total 14 common peaks obtained, 8 corresponded The similarity fingerprints ranged from 0.814 0.998. Principal component analysis (PCA) hierarchical cluster (HCA) performed study. content astaxanthin 0.401% 0.867%. This consistent with results PCA HCA analysis, revealed differences between obtained different manufacturers. We studied Caenorhabditis . elegans found that effectively prolong lifespan C. , reduce accumulation lipofuscin, increase frequency exercise. addition, it was enhance heat stress resistance improve activity enzymes (MDA, SOD, CAT, GSH). combination HPLC fingerprint chemical pattern recognition reliable stable be applied systematic evaluation study as model organism has an certain application food medicine, provides new idea development

Язык: Английский

Процитировано

0