Interdisciplinary cancer research,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 1, 2024
Cancer
is
a
global
health
challenge,
with
rapidly
rising
incidence
and
significant
economic
burden.
The
urgent
need
for
innovative
approaches
to
cancer
prevention
treatment
underscored
by
its
growing
impact.
Marine
algae,
characterized
their
unique
bioactive
compounds,
have
emerged
as
promising
sources
of
novel
anticancer
agents
in
this
context.
This
chapter
reviews
the
potential
marine
algae
treatment,
emphasizing
integration
traditional
knowledge
modern
scientific
methods
develop
safe,
affordable,
accessible
drugs.
offer
rich
source
including
polysaccharides,
polyphenols,
pigments,
known
antioxidant,
anti-inflammatory,
antitumor
effects.
Moreover,
these
organisms
evolved
complex
defense
mechanisms,
making
them
particularly
interesting
drug
discovery.
Research
highlights
multifaceted
mechanisms
apoptosis
induction,
cell
cycle
arrest,
selective
cytotoxicity
against
cells.
Fucoxanthin,
fucoidan,
stigmasterol,
other
compounds
from
shown
potent
properties
through
modulation
various
signaling
pathways.
advantages
include
chemical
diversity,
sustainability,
environmentally
friendly
cultivation,
presenting
exciting
opportunities
development.
To
address
challenges
herbal
medicine,
standardization,
active
compound
identification,
rigorous
clinical
trials
are
essential.
Collaboration
between
practitioners
scientists
can
bridge
gap
wisdom
medical
standards.
Combinatorial
therapies
that
integrate
extracts
conventional
treatments
more
effective
holistic
management.
Nutraceuticals,
Год журнала:
2024,
Номер
4(1), С. 50 - 64
Опубликована: Янв. 18, 2024
In
recent
years,
the
emergence
of
drug
resistance
and
sensitivity
in
leading
diseases
has
heightened
global
interest
natural
nutraceuticals
as
primary
health
supplements.
However,
comprehensive
scientific
scrutiny
is
essential
before
marketing
these
this
study,
we
assessed
nutritional
composition,
antioxidant
activities,
trace
metal
accumulation
eleven
selected
Sri
Lankan
coastal
seaweed
species.
Gracilaria
corticata
had
highest
(p
<
0.05)
ash
crude
fiber
content
among
Protein
ranged
from
4.87%
to
23.67%
(DW),
with
Ulva
rigida
displaying
0.05).
Crude
fat
0.09%
4.13%
Cladophora
herpestica
having
content.
Sargassam
cinereum,
Turbinaria
ornata
Sargassum
crassifolium
TPC
(51.32
±
0.61–28.90
2.68
mg/GAE
g)
radical
scavenging
activity
compared
other
seaweeds.
The
study
findings
indicate
that
most
studied
metals
seaweeds
exceeded
WHO-recommended
levels.
Aluminum
was
accumulated
metals.
Toxic
heavy
metals,
such
arsenic,
cadmium
chromium,
levels
all
surpassed
WHO
limits.
While
displayed
acceptable
properties,
presence
poses
a
potential
risk
consumers.
Products
using
may
have
lower
quality.
Thus,
underscores
need
for
investigation
developing
high-quality
food
products
or
supplements
Molecules,
Год журнала:
2024,
Номер
29(8), С. 1900 - 1900
Опубликована: Апрель 22, 2024
Non-communicable
diseases
(NCDs)
represent
a
global
health
challenge,
constituting
major
cause
of
mortality
and
disease
burden
in
the
21st
century.
Addressing
prevention
management
NCDs
is
crucial
for
improving
public
health,
emphasizing
need
comprehensive
strategies,
early
interventions,
innovative
therapeutic
approaches
to
mitigate
their
far-reaching
consequences.
Marine
organisms,
mainly
algae,
produce
diverse
marine
natural
products
with
significant
potential.
Harnessing
largely
untapped
potential
algae
could
revolutionize
drug
development
contribute
combating
NCDs,
marking
step
toward
targeted
approaches.
This
review
examines
bioactive
extracts,
compounds,
commercial
derived
from
macro-
microalgae,
exploring
protective
properties
against
oxidative
stress,
inflammation,
cardiovascular,
gastrointestinal,
metabolic
diseases,
cancer
across
vitro,
cell-based,
vivo,
clinical
studies.
Most
research
focuses
on
macroalgae,
demonstrating
antioxidant,
anti-inflammatory,
cardioprotective,
gut
modulation,
promotion,
anti-cancer
effects.
Microalgae
also
exhibit
properties.
Although
studies
investigated
extracts
fractions,
isolated
compounds
have
been
explored.
Notably,
polysaccharides,
phlorotannins,
carotenoids,
terpenes
emerge
as
prominent
collectively
representing
42.4%
compounds.
Physiologia Plantarum,
Год журнала:
2024,
Номер
176(3)
Опубликована: Май 1, 2024
Caulerpa
is
a
marine
green
macroalga
distinguished
by
large
single
cell
with
multiple
nuclei.
It
also
exhibits
remarkable
morphological
intraspecies
variations,
in
response
to
diverse
environmental
types.
However,
the
molecular
mechanisms
underlying
this
phenotypic
plasticity
remain
poorly
understood.
In
work,
we
compare
transcriptomes
of
okamurae
Weber
Bosse,
1897
displaying
altered
phenotypes
cultivation
and
natural
investigate
significantly
regulated
genes
their
biological
functions
using
differential
expression
analyses.
We
observe
light-harvesting
complex
upregulation
cellular
framework
stability
downregulation
compared
phenotypes.
Intertidal
macrophytes
reduce
light
capture
avoid
photodamage
regulate
morphology
protect
against
wave
damage.
contrast,
lower
conditions
environment
augment
increase
prioritizing
trapping.
Moreover,
addition
simulated
wave-sweeping
stimuli
induces
return
under
high-light
conditions,
showing
how
mechanical
stress
affects
organization
C.
okamurae.
provide
detailed
gene
patterns
varying
intensities
water
suggesting
distinct
influence
on
its
traits.
Interdisciplinary cancer research,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 1, 2024
Cancer
is
a
global
health
challenge,
with
rapidly
rising
incidence
and
significant
economic
burden.
The
urgent
need
for
innovative
approaches
to
cancer
prevention
treatment
underscored
by
its
growing
impact.
Marine
algae,
characterized
their
unique
bioactive
compounds,
have
emerged
as
promising
sources
of
novel
anticancer
agents
in
this
context.
This
chapter
reviews
the
potential
marine
algae
treatment,
emphasizing
integration
traditional
knowledge
modern
scientific
methods
develop
safe,
affordable,
accessible
drugs.
offer
rich
source
including
polysaccharides,
polyphenols,
pigments,
known
antioxidant,
anti-inflammatory,
antitumor
effects.
Moreover,
these
organisms
evolved
complex
defense
mechanisms,
making
them
particularly
interesting
drug
discovery.
Research
highlights
multifaceted
mechanisms
apoptosis
induction,
cell
cycle
arrest,
selective
cytotoxicity
against
cells.
Fucoxanthin,
fucoidan,
stigmasterol,
other
compounds
from
shown
potent
properties
through
modulation
various
signaling
pathways.
advantages
include
chemical
diversity,
sustainability,
environmentally
friendly
cultivation,
presenting
exciting
opportunities
development.
To
address
challenges
herbal
medicine,
standardization,
active
compound
identification,
rigorous
clinical
trials
are
essential.
Collaboration
between
practitioners
scientists
can
bridge
gap
wisdom
medical
standards.
Combinatorial
therapies
that
integrate
extracts
conventional
treatments
more
effective
holistic
management.
