International Journal of Biological Macromolecules, Год журнала: 2025, Номер 298, С. 140124 - 140124
Опубликована: Янв. 20, 2025
Язык: Английский
Процитировано
1Targeted cancer treatment using folate-conjugated sponge-like ZIF-8 nanoparticles: a review
Naunyn-Schmiedeberg s Archives of Pharmacology, Год журнала: 2023, Номер 397(3), С. 1377 - 1404
Опубликована: Сен. 16, 2023
Язык: Английский
Процитировано
15Current Understanding of the Molecular Basis of Spices for the Development of Potential Antimicrobial Medicine
Antibiotics, Год журнала: 2023, Номер 12(2), С. 270 - 270
Опубликована: Янв. 29, 2023
Antimicrobial resistance increases day by around the world. To overcome this situation new antimicrobial agents are needed. Spices such as clove, ginger, coriander, garlic, and turmeric have potential to fight resistant microbes. Due their therapeutic properties, medicinal herbs spices been utilized herbal medicines since antiquity. They important sources of organic antibacterial substances that employed in treating infectious disorders caused pathogens bacteria. The main focus study is bioactivity active ingredients present different kinds naturally available spices. We conducted a thorough search PubMed, Google Scholar, Research Gate for review. read many literature, paper, we conclude perform some form bioactivity. After reading several papers, found good antifungal which may help controlling emerging improving human health. phytochemicals, show effects. This review literature concludes natural bioactivate compounds can be used drug beings.
Язык: Английский
Процитировано
13Curcuma Longa: Nutraceutical Use and Association With Nanotechnology
Advanced Healthcare Materials, Год журнала: 2024, Номер 13(22)
Опубликована: Май 7, 2024
Curcumin is a natural product found in the rhizome of Curcuma longa (L.) and other spp. As lipophilic molecule, it has greater affinity for polar, non-polar, alkaline, or extremely acidic organic solvents. Several studies indicate that curcumin several benefits human health, example, against degenerative diseases, cancer, infectious diseases. To obtain quality with nutraceutical properties, necessary to know its physicochemical characteristics preserve from cultivation until ingestion by human. However, low solubility leads absorption; this context, nanotechnological systems can contribute increase bioavailability. This review aims highlight important issues all stages goes through: aspects related extraction association nanotechnology. Although process already well established, possible observe more research focused on increasing yield being environmentally friendly. Further, curcumin's absorption notable due characteristics, mainly aqueous solubility. nanotechnology shows be promising an increasingly growing trend because use "Indian solid gold" hope many patients.
Язык: Английский
Процитировано
5Eco-friendly Nanoparticle Phytosynthesis via Plant Extracts: Mechanistic Insights, Recent Advances, and Multifaceted Uses
Nano TransMed, Год журнала: 2025, Номер unknown, С. 100080 - 100080
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0Research Progress of Protein-Based Bioactive Substance Nanoparticles
Foods, Год журнала: 2023, Номер 12(16), С. 2999 - 2999
Опубликована: Авг. 9, 2023
Bioactive substances exhibit various physiological activities-such as antimicrobial, antioxidant, and anticancer activities-and have great potential for application in food, pharmaceuticals, nutraceuticals. However, the low solubility, chemical instability, bioavailability of bioactive limit their food industry. Using nanotechnology to prepare protein nanoparticles encapsulate deliver active is a promising approach due abundance, biocompatibility, biodegradability proteins. Common protein-based nanocarriers include nano-emulsions, nano-gels, nanoparticles, nano complexes. In this review, we give an overview nanoparticle fabrication methods, highlighting pros cons. Additionally, discuss applications current issues regarding utilization Finally, provide perspectives on future development directions, with focus classifying functional properties.
Язык: Английский
Процитировано
11Immunoregulatory effects of nanocurcumin in inflammatory milieu: Focus on COVID-19
Biomedicine & Pharmacotherapy, Год журнала: 2024, Номер 171, С. 116131 - 116131
Опубликована: Янв. 9, 2024
The use of natural compounds, such as curcumin, to treat infections caused by bacteria, viruses, fungi, parasites, inflammatory diseases, and various types cancer is an active dynamic area research. Curcumin has a long history in the food industry, there currently growing interest its therapeutic applications. Numerous clinical trials have consistently shown that polyphenolic compound, safe well-tolerated even at high doses. There no toxicity limit. However, efficacy curcumin been limited constraints. scientific evidence indicates adjuvants carriers, nanoparticles, exosomes, micelles, liposomes, can help overcome this limitation. properties, functions, human benefits using nanocurcumin are well-supported Recent suggests may be beneficial modality due potential decrease gene expression secretion specific biomarkers involved cytokinestorm seen severe COVID-19, well increase lymphocyte counts. Nanocurcumin demonstrated ability improve manifestations modulate immune response inflammation autoinflammatory diseases. Additionally, efficacy, affordability, safety make it promising replacement for residual cells after tumor removal. further studies necessary evaluate new trials, including appropriate dosage, frequency, duration.
Язык: Английский
Процитировано
4A narrative review on the use of Green synthesized metallic nanoparticles for targeted cancer therapy
Bioorganic Chemistry, Год журнала: 2025, Номер 157, С. 108305 - 108305
Опубликована: Фев. 23, 2025
Язык: Английский
Процитировано
0Anticancer activity of curcumin-loaded nanocarriers: A focus on combined therapeutic modalities
Studies in natural products chemistry, Год журнала: 2025, Номер unknown, С. 1 - 39
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0Green Nanotechnology: Naturally Sourced Nanoparticles as Antibiofilm and Antivirulence Agents Against Infectious Diseases
International Journal of Microbiology, Год журнала: 2025, Номер 2025(1)
Опубликована: Янв. 1, 2025
The escalating threat of infectious diseases, exacerbated by antimicrobial resistance (AMR) and biofilm formation, necessitates innovative therapeutic strategies. This review presents a comprehensive exploration the potential nanoparticles synthesized from natural sources, including plant extracts, microbial products, marine compounds, as agents. These naturally derived demonstrated significant antibiofilm antivirulence effects, with specific examples revealing their capacity to reduce mass up 78% inhibit bacterial quorum sensing 65%. integration bioactive such polyphenols chitosan, facilitates nanoparticle stability enhances efficacy, while green synthesis protocols environmental risks. Notably, identifies silver using tea achieving 85% inhibition polymicrobial growth in vitro. Despite these promising results, challenges standardization scalability persist. study underscores transformative leveraging sourced sustainable alternatives conventional antimicrobials, offering quantitative insights for future application combating mono- infections.
Язык: Английский
Процитировано
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