Nutrition Research, Год журнала: 2024, Номер 134, С. 24 - 38
Опубликована: Дек. 26, 2024
Язык: Английский
Cureus, Год журнала: 2024, Номер unknown
Опубликована: Окт. 13, 2024
Magnesium (Mg), an essential mineral abundantly present within the human body, is intricately involved in a multitude of biochemical processes vital for maintaining health and overall well-being. This review aims to delve into multifaceted impact Mg on health, exploring its physiological functions, dietary sources, potential implications deficiency or insufficiency. plays pivotal role various processes, including energy metabolism, muscle contraction, protein synthesis, DNA synthesis. It acts as cofactor more than 300 enzymatic reactions, facilitating conversion adenosine triphosphate (ATP) diphosphate (ADP) production. Moreover, proper functioning ion channels, particularly calcium influencing nerve transmission relaxation. naturally found wide array foods, with green leafy vegetables, whole grains, nuts, seeds, legumes being rich sources. Additionally, certain fortified foods supplements provide supplemental intake. Deficiency insufficiency mg can have profound health. Inadequate levels been associated increased risks chronic diseases, hypertension, type 2 diabetes, osteoporosis, cardiovascular diseases. Furthermore, may manifest symptoms such weakness, fatigue, tremors, irregular heartbeat. Numerous studies elucidated relationship between intake risk developing For instance, epidemiological evidence suggests that higher reduced possibly due vasodilatory effects influence blood pressure regulation mechanisms. Similarly, has implicated pathophysiology contributing insulin resistance impaired glucose metabolism. adequate crucial bone density reducing mineralization Understanding importance physiology underscores significance ensuring through diet supplementation. Healthcare professionals play critical educating individuals about incorporating mg-rich their diets considering supplementation when necessary, at those indispensable far-reaching Its involvement Ensuring preventing deficiency-related complications Further research warranted elucidate optimal strategies therapeutic applications disease prevention management.
Язык: Английский
Процитировано
8
Scientific Reports, Год журнала: 2025, Номер 15(1)
Опубликована: Апрель 12, 2025
This study investigates the association between dietary methyl donor nutrients intake and phenotypic aging. cross-sectional comprised 27,211 adult participants from NHANES 2005-2018. The methyl-donor nutritional quality index (MNQI) was calculated by assessing of seven nutrients: protein, folate, choline, riboflavin, vitamin B6, B12, zinc. Phenotypic age acceleration (PhenoAge.Accel) using biochemical markers to assess biological Weighted generalized linear regression models were utilized associations MNQI PhenoAge.Accel, impact different demographic health characteristics evaluated through interaction effect tests. After adjusting for various potential confounding factors, a significant negative found PhenoAge.Accel (β = - 0.66; 95% CI 0.91, 0.40; P < 0.0001), indicating that an increase in is associated with slowdown PhenoAge.Accel. Furthermore, subgroup analysis indicated stronger negatively males 0.94; 1.36, 0.52) interactions (Pinteraction 0.02). In populations, PhenoAge Accel, suggesting choosing high-quality foods can help develop effective strategies enhance healthy longevity.
Язык: Английский
Процитировано
0
Nutrients, Год журнала: 2024, Номер 16(23), С. 4164 - 4164
Опубликована: Ноя. 30, 2024
The dietary index for gut microbiota (DI-GM) is a newly proposed metric assessing diet quality, and its relationship with biological age unclear. We hypothesize that consuming foods conducive to healthy environment may decelerate aging.
Язык: Английский
Процитировано
4
Frontiers in Nutrition, Год журнала: 2025, Номер 12
Опубликована: Янв. 22, 2025
Background Oxidative stress has been reported to participant in the pathogenesis of gallstones. balance score (OBS) represents pro-oxidant and antioxidant exposures diet lifestyle, closely associated with multiple metabolic disorders. However, relationship between OBS gallstones remains unclear. Methods This study analyzed cross-sectional data from National Health Nutrition Examination Survey (NHANES) 2017–2020. was calculated based on 24-h recall interviews or questionnaires. We used weighted logistic regression, restricted cubic splines (RCS), quantile sum (WQS) regression Bayesian kernel machine (BKMR) model identify Subgroup analysis sensitivity were explore potential heterogeneity stability results. Mediation performed assess mediating effects serum lipid association Results A total 7,618 participants finally included this study. Weighted logistics showed that risk (OR = 0.98, p 0.03), particularly individuals who under 60 years old, Hispanic, educated below high school, non-smokers, had hypertension malignancy. Dietary lifestyle independently contribute protection against RCS indicated a non-linear ( 0.03). WQS BKMR identified BMI, vitamin E, B6, magnesium carotene played relatively important role among 20 components. TG HDL as mediators Conclusion Higher increased oxidative are positively reduction gallstone risk. findings provide valuable insights for surveillance interventions targeting antioxidant-rich disease.
Язык: Английский
Процитировано
0
Frontiers in Nutrition, Год журнала: 2024, Номер 11
Опубликована: Дек. 11, 2024
This is the initial investigation assessing association between caffeine consumption through diet and circulating Klotho concentrations, with being recognized as a key biomarker of healthspan aging.
Язык: Английский
Процитировано
0
Nutrition Research, Год журнала: 2024, Номер 134, С. 24 - 38
Опубликована: Дек. 26, 2024
Язык: Английский
Процитировано
0