The Expanding Role of Probiotics in Human Health
Nutrients,
Год журнала:
2025,
Номер
17(7), С. 1116 - 1116
Опубликована: Март 24, 2025
Since
the
1990s,
it
has
been
widely
documented
that
probiotics,
either
alone
or
in
combination
with
prebiotic
supplements,
play
a
vital
role
host
health
and
disease
management
[...].
Язык: Английский
Skin Protection Effects of Lactobacillus paragasseri HN910 Lysate and the Role of Alanine
Probiotics and Antimicrobial Proteins,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 17, 2025
Abstract
Skin
aging
is
influenced
by
structural
alterations,
oxidative
stress,
inflammation,
and
microbiome
changes,
a
comprehensive
approach
to
addressing
these
factors
may
be
effective
for
mitigating
skin
aging.
This
study
evaluates
the
multifaceted
anti-aging
effects
of
heat-killed
(HK-HN910)
lysed
(LS-HN910)
forms
Lactobacillus
paragasseri
HN910.
Protective
on
cell
viability,
permeability,
nitric
oxide
(NO)
production,
gene
expression
both
HK-HN910
LS-HN910
were
observed.
Both
significantly
enhanced
tight
junction
(TJ)
protein
zonula
occludens-
1
(
ZO-
)
antioxidant
enzyme
glutathione
peroxidase
GPx)
expression,
while
downregulating
that
senescence-associated
secretory
phenotype
pro-inflammatory
cytokines
interleukin
IL
-
1α
,
IL-
1β
6
8
tumor
necrosis
factor-alpha
TNFα
).
showed
greater
upregulation
GPx
downregulation
compared
HK-HN910.
Cell
wall
component
D-alanine
(D-Ala)
was
released
in
higher
amounts
than
demonstrated
effects.
D-Ala
upregulated
barrier
claudin-
Cla-
),
occludin
OCC
filaggrin
FLG
sphingomyelin
phosphodiesterase
2
SMPD2
enzymes
superoxide
dismutase
SOD
catalase
CAT
.
treatment
clinically
revealed
improvements
parameters,
including
transepidermal
water
loss,
contents,
sebum
levels,
dermal
density,
eye
wrinkle
index,
pH,
brightness,
microbiota
composition,
with
significant
increase
Rhodococcus
abundance.
These
findings
indicate
LS-HN910,
containing
D-Ala,
promising
cosmeceutical
preventing
enhancing
barrier,
promoting
defense,
modulating
inflammatory
responses,
influencing
microbiota.
Язык: Английский
Probiotic effects on skin health: comprehensive visual analysis and perspectives
Frontiers in Microbiology,
Год журнала:
2024,
Номер
15
Опубликована: Дек. 3, 2024
Bacteria
play
a
crucial
role
in
maintaining
the
health
of
human
skin.
Research
has
demonstrated
that
probiotics
present
notable
benefits
for
extraintestinal
organs.
Despite
extensive
research
on
impact
skin
health,
there
is
absence
regulatory
frameworks
governing
their
external
application,
with
no
approval
from
FDA
any
probiotic
products
use.
The
aim
this
study
to
offer
thorough
summary
status
field
since
2000
and
project
future
trends.
Язык: Английский