Exploring Mycosporine-like Amino Acid UV-Absorbing Natural Products for a New Generation of Environmentally Friendly Sunscreens DOI Creative Commons
Nedeljka Rosić, Mike Climstein, Glen M. Boyle

и другие.

Marine Drugs, Год журнала: 2023, Номер 21(4), С. 253 - 253

Опубликована: Апрель 19, 2023

Human skin needs additional protection from damaging ultraviolet radiation (UVR: 280–400 nm). Harmful UVR exposure leads to DNA damage and the development of cancer. Available sunscreens offer chemical detrimental sun a certain extent. However, many synthetic do not provide sufficient due lack photostability their UV-absorbing active ingredients and/or ability prevent formation free radicals, inevitably leading damage. In addition, may negatively affect human skin, causing irritation, accelerating aging even resulting in allergic reactions. Beyond potential negative effect on health, some have been shown harmful impact environment. Consequently, identifying photostable, biodegradable, non-toxic, renewable natural UV filters is imperative address health sustainable environmental solution. nature, marine, freshwater, terrestrial organisms are protected through several important photoprotective mechanisms, including synthesis compounds such as mycosporine-like amino acids (MAAs). MAAs, other promising, products could be considered for future sunscreens. This review investigates necessity using protection, specifically that more environmentally friendly than filters. Critical challenges limitations related MAAs sunscreen formulations also evaluated. Furthermore, we explain how genetic diversity MAA biosynthetic pathways linked bioactivities assess MAAs’ applications health.

Язык: Английский

The response of aquatic ecosystems to the interactive effects of stratospheric ozone depletion, UV radiation, and climate change DOI Creative Commons
Patrick J. Neale, Craig E. Williamson, Anastazia T. Banaszak

и другие.

Photochemical & Photobiological Sciences, Год журнала: 2023, Номер 22(5), С. 1093 - 1127

Опубликована: Май 2, 2023

Variations in stratospheric ozone and changes the aquatic environment by climate change human activity are modifying exposure of ecosystems to UV radiation. These shifts have consequences for distributions species, biogeochemical cycles, services provided ecosystems. This Quadrennial Assessment presents latest knowledge on multi-faceted interactions between effects irradiation change, other anthropogenic activities, how these conditions changing Climate results variations depth mixing, thickness ice cover, duration ice-free inputs dissolved organic matter, all which can either increase or decrease Anthropogenic activities release oil, filters sunscreens, microplastics into that then modified radiation, frequently amplifying adverse organisms their environments. The impacts combination with factors such as warming ocean acidification considered micro-organisms, macroalgae, plants, animals (floating, swimming, attached). Minimising disruptive critical world's rivers, lakes oceans (freshwater supply, recreation, transport, food security) will not only require continued adherence Montreal Protocol but also a wider inclusion solar radiation its studies and/or models under future global climate.

Язык: Английский

Процитировано

51
Therapeutic Potential of Polyphenols and Other Micronutrients of Marine Origin DOI Creative Commons
Leonel Pereira, João Cotas

Marine Drugs, Год журнала: 2023, Номер 21(6), С. 323 - 323

Опубликована: Май 26, 2023

Polyphenols are compounds found in various plants and foods, known for their antioxidant anti-inflammatory properties. Recently, researchers have been exploring the therapeutic potential of marine polyphenols other minor nutrients that algae, fish crustaceans. These unique chemical structures exhibit diverse biological properties, including anti-inflammatory, antioxidant, antimicrobial antitumor action. Due to these being investigated as possible agents treatment a wide variety conditions, such cardiovascular disease, diabetes, neurodegenerative diseases cancer. This review focuses on applications human health, also, phenolic classes, extraction methods, purification techniques future compounds.

Язык: Английский

Процитировано

44
The microalgal sector in Europe: towards a sustainable bioeconomy DOI Creative Commons
Irene Gallego, Nikola Medić, Jakob Skov Pedersen

и другие.

New Biotechnology, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Microalgae are a diverse group of photosynthetic microorganisms that can be exploited to produce sustainable food and feed products, alleviate environmental pollution, or sequester CO

Язык: Английский

Процитировано

3
Development of CRISPR-Cas9-Based Genome Editing Tools for Non-model Microorganism Erwinia persicina DOI Creative Commons
Tingfeng Cheng, Xinyan Cao, Yuchen Wang

и другие.

Synthetic and Systems Biotechnology, Год журнала: 2025, Номер 10(2), С. 555 - 563

Опубликована: Фев. 19, 2025

Erwinia persicina is a bacterium that has been known to produce secondary metabolites, such as andrimid, pink pigment, and exopolysaccharides, infect more than twenty plant species. However, traditional gene manipulation methods have hindered by the inefficient of suicide plasmid-mediated genome editing. In this study, we describe successful application CRISPR-Cas9 system in E. persicina. Efficient editing was achieved substituting native gRNA promoter with J23119 single-plasmid (pRed_Cas9_ΔpoxB) optimizing design. The use double gRNAs led deletion 42 kb genomic fragment, incorporation sacB screening marker facilitated iterative knockouts. Additionally, 22 plasmid containing self-resistance conjugally transferred into persicina, resulting insertion 6.4 fragment 100 % efficiency. Furthermore, demonstrated expression shinorine, an anti-UV compound, within chassis. This study establishes promising chassis for synthetic biology provides model gene-editing systems non-model microorganisms.

Язык: Английский

Процитировано

2
Seaweed-Based Molecules and Their Potential Biological Activities: An Eco-Sustainable Cosmetics DOI Creative Commons
Haresh S. Kalasariya, Virendra Kumar Yadav, Krishna Kumar Yadav

и другие.

Molecules, Год журнала: 2021, Номер 26(17), С. 5313 - 5313

Опубликована: Сен. 1, 2021

Amongst the countless marine organisms, seaweeds are considered as one of richest sources biologically active ingredients having powerful biological activities. Seaweeds or macroalgae macroscopic multicellular eukaryotic photosynthetic organisms and have potential to produce a large number valuable compounds, such proteins, carbohydrates, fatty acids, amino phenolic pigments, etc. Since it is prominent source bioactive constituents, finds diversified industrial applications viz food dairy, pharmaceuticals, medicinal, cosmeceutical, nutraceutical, Moreover, seaweed-based cosmetic products risen up in their demands by consumers, they see them promising alternative synthetic cosmetics. Normally contains purified compounds extracts with several compounds. Several seaweed that useful cosmeceuticals known be effective alternatives significant benefits. Many seaweeds’ species demonstrated skin beneficial activities, antioxidant, anti-melanogenesis, antiaging, photoprotection, anti-wrinkle, moisturizer, anti-inflammatory, anticancer antioxidant properties, well certain antimicrobial antibacterial, antifungal antiviral This review presents molecules derived from algae substitute for its current industry. The activities pigments discussed safe consumer

Язык: Английский

Процитировано

77
Perspectives on the microorganism of extreme environments and their applications DOI Creative Commons
Nikita Kochhar,

Kavya I.K,

Shrashti Shrivastava

и другие.

Current Research in Microbial Sciences, Год журнала: 2022, Номер 3, С. 100134 - 100134

Опубликована: Янв. 1, 2022

Extremophiles are organisms that can survive and thrive in conditions termed as "extreme" by human beings. Conventional methods cannot be applied under extreme like temperature pH fluctuations, high salinity, etc. for a variety of reasons. function adapted to these environments sustainable, cheaper, efficient, therefore, they serve better alternatives the traditional methods. They adapt with biochemical physiological changes produce products extremolytes, extremozymes, biosurfactants, etc., which found useful wide range industries sustainable agriculture, food, cosmetics, pharmaceuticals. These also play crucial role bioremediation, production biofuels, biorefinery, astrobiology. This review paper comprehensively lists out current applications extremophiles their various explores prospects same. help us understand underlying basis biological mechanisms exploring boundaries life thus origin evolution on Earth. helps research extra-terrestrial space exploration. The structure properties along any possible long-term effects need investigated further.

Язык: Английский

Процитировано

69
Algal nutraceuticals: A perspective on metabolic diversity, current food applications, and prospects in the field of metabolomics DOI
Pascual García-Pérez, Lucía Cassani, Paula García-Oliveira

и другие.

Food Chemistry, Год журнала: 2022, Номер 409, С. 135295 - 135295

Опубликована: Дек. 23, 2022

Язык: Английский

Процитировано

45
Biomolecules from Macroalgae—Nutritional Profile and Bioactives for Novel Food Product Development DOI Creative Commons

Laura E. Healy,

Xianglu Zhu, Milica Pojić

и другие.

Biomolecules, Год журнала: 2023, Номер 13(2), С. 386 - 386

Опубликована: Фев. 17, 2023

Seaweed is in the spotlight as a promising source of nutrition for humans search sustainable food production systems continues. has well-documented rich nutritional profile containing compounds such polyphenols, carotenoids and polysaccharides well proteins, fatty acids minerals. processing extraction functional ingredients alginate, agar, carrageenan well-established. Novel pretreatments ultrasound assisted or high-pressure can be incorporated to more efficiently extract these targeted ingredients. The scope products that created using seaweed are wide ranging: from bread noodles yoghurt milk even an ingredient enhance stability meat products. There opportunities producers this area develop novel seaweed. This review paper discusses unique properties food, processes involved aquaculture, developed marine biomass. Challenges facing industry consumer hesitation around products, safety seaweed, hurdles will also discussed.

Язык: Английский

Процитировано

41
Photoprotective role of plant secondary metabolites: Biosynthesis, photoregulation, and prospects of metabolic engineering for enhanced protection under excessive light DOI
Maneesh Lingwan,

Ajar Anupam Pradhan,

Amit Kumar Kushwaha

и другие.

Environmental and Experimental Botany, Год журнала: 2023, Номер 209, С. 105300 - 105300

Опубликована: Март 22, 2023

Язык: Английский

Процитировано

33
Natural Sun-Screening Compounds and DNA-Repair Enzymes: Photoprotection and Photoaging DOI Open Access
Amit Gupta, Ashish P. Singh, Varsha Singh

и другие.

Catalysts, Год журнала: 2023, Номер 13(4), С. 745 - 745

Опубликована: Апрель 13, 2023

Ultraviolet radiation (UVR) has been scientifically proven to cause skin disorders such as sunburn, cancer and the symptoms of chronic exposure. Natural sun screening compounds have recently gained tremendous attention from cosmetic cosmeceutical sectors for treating hyperpigmentation aging. A wide range natural UV-absorbing used replace or reduce number synthetic sunscreen molecules. One primary causes photoaging is DNA damage, mainly caused by UVR. Photoprotection provided traditional sunscreens purely preventative no efficacy after damage initiated. As a result, quest DNA-repair mechanisms that block, reverse, postpone pathologic processes in UV-exposed stimulated anti-photoaging research methods increase effectiveness sunscreens. This review summarizes many microalgae, lichens, plants demonstrated potential photoprotection effects against UV radiation-induced damage. Furthermore, it offers an overview current breakthroughs enzymes utilized their influence on photoaging.

Язык: Английский

Процитировано

25