Yellow
pitahaya
is
a
tropical
fruit
that
has
gained
popularity
in
recent
years.
Natural
elicitors
are
compounds
can
stimulate
the
resistance
and
quality
of
fruits.
The
objective
this
study
was
to
evaluate
effects
natural
elicitors:
methyl
salicylate
(MeSa),
jasmonate
(JaMe),
salicylic
acid
(SA)
oxalic
(OA)
at
concentrations
0.1
mM
(SaMe
JaMe)
5
(SA
OA),
applied
yellow
fruits,
under
greenhouse
conditions.
After
full
blossom,
4
applications
were
made
with
frequency
15
days.
At
time
harvest
after
storage,
following
variables
evaluated:
firmness
(whole
fruit),
total
soluble
solids
(TSS),
acidity
(TA),
phenolics
carotenoids
(in
pulp),
while
phenolics,
carotenoids,
macronutrients
micronutrients
determined
peel.
results
showed
JaMe
presented
delay
ripening
process,
according
TSS,
TA,
firmness,
phenolic
results,
MeSa
advanced
maturation.
Regarding
alternative
use
peel
as
by-product,
application
significantly
increased
content
polyphenols,
peel,
which
be
used
bioactive
compound
food
industry.
In
conclusion,
indicate
an
improve
shelf
life
Cells,
Год журнала:
2024,
Номер
13(13), С. 1098 - 1098
Опубликована: Июнь 25, 2024
Migraine
is
a
debilitating
neurological
disorder
characterized
by
recurring
episodes
of
throbbing
headaches
that
are
frequently
accompanied
sensory
disturbances,
nausea,
and
sensitivity
to
light
sound
[...]
Journal of Neural Transmission,
Год журнала:
2024,
Номер
131(12), С. 1367 - 1387
Опубликована: Авг. 7, 2024
Millions
of
individuals
around
the
world
are
afflicted
with
Parkinson's
disease
(PD),
a
prevalent
and
incapacitating
neurodegenerative
disorder.
Dr.
Reichmann,
distinguished
professor
neurologist,
has
made
substantial
advancements
in
domain
PD
research,
encompassing
both
fundamental
scientific
investigations
practical
applications.
His
research
illuminated
etiology
treatment
PD,
as
well
function
energy
metabolism
premotor
symptoms.
As
precursor
to
number
neurotransmitters
neuromodulators
that
implicated
pathophysiology
he
also
investigated
application
tryptophan
(Trp)
derivatives
disease.
principal
findings
insights
summarized
synthesized
this
narrative
review
article,
which
emphasizes
challenges
implications
for
future
research.
This
aims
identify
analyze
key
contributions
Reichmann
field
ultimate
goal
informing
directions
domain.
By
examining
Reichmann's
work,
study
seeks
provide
comprehensive
understanding
his
major
how
they
can
be
applied
advance
diagnosis
PD.
paper
explores
potential
intersection
emerging
avenues,
such
investigation
Trp
its
metabolites,
particularly
kynurenines,
could
lead
new
therapeutic
strategies
managing
disorders
like
Nutrients,
Год журнала:
2024,
Номер
16(16), С. 2721 - 2721
Опубликована: Авг. 15, 2024
Aging-related
disorders
pose
significant
challenges
due
to
their
complex
interplay
of
physiological
and
metabolic
factors,
including
inflammation,
oxidative
stress,
mitochondrial
dysfunction.
Curcumin,
a
natural
compound
with
potent
antioxidant
anti-inflammatory
properties,
has
emerged
as
promising
candidate
for
mitigating
these
age-related
processes.
However,
gaps
in
understanding
the
precise
mechanisms
curcumin’s
effects
optimal
dosages
different
conditions
necessitate
further
investigation.
This
systematic
review
synthesizes
current
evidence
on
potential
addressing
disorders,
emphasizing
its
impact
cognitive
function,
neurodegeneration,
muscle
health
older
adults.
By
evaluating
safety,
efficacy,
action
curcumin
supplementation,
this
aims
provide
insights
into
therapeutic
promoting
healthy
aging.
A
search
across
three
databases
using
specific
keywords
yielded
2256
documents,
leading
selection
15
clinical
trials
synthesis.
Here,
we
highlight
multifaceted
agent
combating
disorders.
The
findings
suggest
that
could
offer
effective
approach
enhancing
quality
life
aging
individuals.
Further
research
well-designed
are
essential
validate
optimize
use
personalized
medicine
approaches
conditions.
International Journal of Molecular Sciences,
Год журнала:
2025,
Номер
26(2), С. 484 - 484
Опубликована: Янв. 8, 2025
Alzheimer's
disease
(AD)
remains
a
leading
cause
of
cognitive
decline
and
mortality
worldwide,
characterized
by
neurodegeneration,
synaptic
deficiencies,
neuroinflammation.
Despite
advancements
in
early
detection,
diagnosis,
treatment,
AD
presents
substantial
challenges
due
to
its
complex
pathology,
heterogeneity,
the
limited
efficacy
current
therapies.
Consequently,
there
is
pressing
need
for
novel
therapeutic
agents
target
multifaceted
aspects
enhance
treatments,
minimize
adverse
effects.
AdipoRon,
an
adiponectin
receptor
agonist,
has
garnered
interest
potential
neuroprotective
effects,
including
reducing
neuroinflammation,
improving
mitochondrial
function,
mitigating
tau
hyperphosphorylation.
This
review
aimed
evaluate
effects
AdipoRon-based
replacement
therapy
against
AD,
using
comprehensive
approach
grounded
PICO
framework-Population,
Intervention,
Comparison,
Outcomes.
A
total
six
studies
were
reviewed,
vitro
vivo
investigations
examining
AdipoRon's
impact
on
various
models.
These
involved
different
cell
lines
transgenic
mouse
models,
assessing
outcomes
such
as
phosphorylation,
relevant
molecular
pathways.
By
synthesizing
data
from
these
studies,
our
thoroughly
explains
mechanisms
action,
agent
AD.
analysis
aims
highlight
state
knowledge,
identify
gaps
research,
suggest
directions
future
clinical
applications.
Plants,
Год журнала:
2023,
Номер
12(18), С. 3212 - 3212
Опубликована: Сен. 8, 2023
Pitaya
is
one
of
the
fruit
species
whose
demand
has
increased
in
recent
years
due
to
numerous
health
benefits
and
lucrative
price
its
by-products.
In
Europe,
Iberian
Peninsula
other
Mediterranean
countries
are
ones
with
favorable
climatic
conditions
for
cultivation.
This
document
describes
much
history
pitaya
difficulties
related
A
bibliographical
survey
was
carried
out
on
culture
world,
focusing
edaphoclimatic
requirements,
possibility
this
becoming
a
consolidated
crop
Peninsula.
The
relatively
low
water
requirement
makes
sustainable
among
crops
that
require
irrigation.
addition,
we
provide
perspective
use
research
emerging
crop.
There
been
an
exponential
growth
scientific
publications
last
decade;
however,
more
needs
be
researched
know
how
increase
productivity
as
well
sensory
quality
fruits
different
regions.
good
option
diversify
production
Foods,
Год журнала:
2025,
Номер
14(5), С. 793 - 793
Опубликована: Фев. 26, 2025
Red
dragon
fruit
juice
(RDFJ)
is
a
common
processing
product
on
the
market,
and
different
methods
can
affect
its
quality.
This
study
selected
traditional
thermal
such
as
pasteurization
novel
non-thermal
like
ultrasonication
cold
plasma
to
treat
red
juice.
The
effects
of
quality
were
comprehensively
evaluated
through
physicochemical
properties,
in
vitro
activity,
metabolomics
flavoromics.
results
indicate
that
cloud
stability
(CP)
treatment
increased
by
16.64%,
total
polyphenol
content
13.76%,
antioxidant
capacity
was
higher
than
other
treatments.
Cold
significantly
L-tyrosine
affected
amino
acid
metabolic
pathways
RDFJ,
which
contribute
phenolic
RDFJ
activity.
CP
effectively
preserved
aroma
components
decreased
harmful
furan
volatile
compounds.
suggest
promising
innovative
technique
RDFJ.
Food Science & Nutrition,
Год журнала:
2023,
Номер
11(6), С. 3442 - 3449
Опубликована: Май 4, 2023
Fermentation
of
fruits
offers
a
diverse
range
flavors,
smells,
and
colors.
Colored
are
rich
in
naturally
occurring
pigments,
such
as
betacyanin.
Hence,
they
considered
to
possess
powerful
antioxidant
activities.
However,
wine
production,
pigments
often
diversify
the
flavor
color
wine.
The
objective
this
study
was
compare
quality
two
types
wines:
single-fruit
(pitaya)
mixed-fruit
that
contains
watermelon
(
