Опубликована: Янв. 1, 2025
Язык: Английский
European Polymer Journal, Год журнала: 2024, Номер 210, С. 112983 - 112983
Опубликована: Март 26, 2024
Язык: Английский
Процитировано
47
International Journal of Biological Macromolecules, Год журнала: 2024, Номер 264, С. 130683 - 130683
Опубликована: Март 6, 2024
Язык: Английский
Процитировано
30
International Journal of Biological Macromolecules, Год журнала: 2024, Номер 273, С. 132916 - 132916
Опубликована: Июнь 5, 2024
Язык: Английский
Процитировано
18
Journal of Materials Chemistry B, Год журнала: 2024, Номер 12(33), С. 7977 - 8006
Опубликована: Янв. 1, 2024
The objective of this review is to provide an up-to-date and all-encompassing account the recent advancements in domain interactive wound dressings. Considering gap between achieved desired clinical outcomes with currently available or under-study healing therapies, newer more specific options based on type phase are reviewed. Starting from comprehensive description process, a detailed classification dressings presented. Subsequently, we present elaborate significant discussion describing (unconventional) Latter includes biopolymer-based, bioactive-containing biosensor-based smart dressings, which discussed separate sections together their applications limitations. Moreover, (2-5 years) trials, patents unconventional marketed products, other information advanced care designs techniques discussed. future research direction highlighted, peptides, proteins, human amniotic membranes as potential Finally, conclude that field needs further development offers scope for integrating process technologies.
Язык: Английский
Процитировано
16
European journal of medical research, Год журнала: 2023, Номер 28(1)
Опубликована: Ноя. 24, 2023
Abstract This paper gives a detailed analysis of nanotechnology's rising involvement in numerous surgical fields. We investigate the use nanotechnology orthopedic surgery, neurosurgery, plastic oncology, heart vascular ophthalmic thoracic and minimally invasive surgery. The details how helps with arthroplasty, chondrogenesis, tissue regeneration, wound healing, more. It also discusses employment nanomaterials implant surfaces, bone grafting, breast implants, among other things. article explores various uses, including stem cell-incorporated nano scaffolds, nano-surgery, hemostasis, nerve nanorobots, diagnostic applications. ethical safety implications using surgery are addressed. future possibilities investigated, pointing to possible route for improved patient outcomes. essay finishes comment on transformational influence applications its promise breakthroughs. Graphical
Язык: Английский
Процитировано
38
Processes, Год журнала: 2023, Номер 11(9), С. 2696 - 2696
Опубликована: Сен. 8, 2023
Biomaterials are mostly any natural and synthetic materials which compatible from a biological point of view with the human body. widely used to sustain, increase, reestablish or substitute function injured tissue organ Additionally, biomaterials uninterruptedly in contact body, i.e., tissue, blood fluids. For this reason, an essential feature is their biocompatibility. Consequently, review summarizes classification different types based on origin, as ones. Moreover, advanced applications pharmaceutical medical domains highlighted specific mechanical physical properties biomaterials, concerning use. The high-priority challenges field also discussed, especially those regarding transfer implementation valuable scientific results practice.
Язык: Английский
Процитировано
30
Journal of Nanobiotechnology, Год журнала: 2024, Номер 22(1)
Опубликована: Май 8, 2024
Abstract Diabetic wounds pose a challenge to healing due increased bacterial susceptibility and poor vascularization. Effective requires simultaneous biofilm elimination angiogenesis stimulation. In this study, we incorporated polyaniline (PANI) S-Nitrosoglutathione (GSNO) into polyvinyl alcohol, chitosan, hydroxypropyltrimethyl ammonium chloride chitosan (PVA/CS/HTCC) matrix, creating versatile wound dressing membrane through electrospinning. The combines the advantages of photothermal antibacterial therapy nitric oxide gas therapy, exhibiting enduring effective bactericidal activity disruption against methicillin-sensitive Staphylococcus aureus , methicillin-resistant Escherichia coli . Furthermore, membrane’s PTT effect NO release exhibit significant synergistic activation, enabling nanodetonator-like burst NIR irradiation disintegrate biofilms. Importantly, nanofiber sustained uniform oxide, thereby catalyzing advancing cellular migration. Ultimately, employment culminated in efficacious amelioration diabetic-infected Sprague–Dawley rats, achieving closure within concise duration 14 days. Upon applying PVA-CS-HTCC-PANI-GSNO membrane, it swiftly eradicates bacteria 5 min, enhancing its inherent anti-biofilm properties powerful action therapy. It also promotes angiogenesis, exhibits excellent biocompatibility, is easy use, highlighting potential treating diabetic wounds. Graphical
Язык: Английский
Процитировано
13
Molecular Pharmaceutics, Год журнала: 2024, Номер 21(3), С. 1056 - 1076
Опубликована: Янв. 30, 2024
Human skin is the largest organ and outermost surface of human body, due to continuous exposure various challenges, it prone develop injuries, customarily known as wounds. Although tissue engineering strategies bioactive wound matrices have been employed speed up healing, scarring remains a significant challenge. The environment harsh presence degradative enzymes elevated pH levels, physiological processes involved in regeneration operate on distinct time scales. Therefore, there need for effective drug delivery systems (DDSs) address these issues. objective this review provide comprehensive exposition mechanisms underlying healing process, factors materials used DDSs, different DDSs care. Furthermore, investigation will delve into examination emergent technologies potential avenues enhancing efficacy care devices.
Язык: Английский
Процитировано
11
International Journal of Biological Macromolecules, Год журнала: 2024, Номер 266, С. 131187 - 131187
Опубликована: Март 28, 2024
Язык: Английский
Процитировано
11
Engineered Regeneration, Год журнала: 2024, Номер 5(1), С. 111 - 123
Опубликована: Янв. 14, 2024
The use of antibacterial dressings is crucial in the prevention and treatment wound infection emergency situations. However, efficacy compromised by long-term storage or exposure to harsh conditions. Here, an ultrastable in-situ silver nanoparticle dressing (AgSNP@CD) was prepared for effective emergency. fabrication process AgSNP@CD simple, suitable large-scale production. Due strong interaction between synthesized AgNPs cotton fabric, owned remarkable stability, thus retaining its antimicrobial even after (up 2 years) under extreme conditions (damp heat, low temperatures, low-oxygen, water immersion, acid-alkali erosion). Both vitro vivo results demonstrated extraordinary stability AgSNP@CD, facilitating healing In particular, exhibited a superior effect on severe bacteria-infected trauma can prevent occurrence sepsis effectively. exceptional complex make it well-suited strategy
Язык: Английский
Процитировано
9