Frontiers in Plant Science,
Год журнала:
2024,
Номер
15
Опубликована: Июль 26, 2024
Forage
maize
is
a
versatile
crop
extensively
utilized
for
animal
nutrition
in
agriculture
and
holds
promise
as
valuable
resource
the
production
of
fermentable
sugars
biorefinery
sector.
Within
this
context,
carbohydrate
fraction
lignocellulosic
biomass
undergoes
deconstruction
during
ruminal
digestion
saccharification
process.
However,
cell
wall's
natural
resistance
towards
enzymatic
degradation
poses
significant
challenge
both
processes.
This
so-called
recalcitrance
primarily
attributed
to
presence
lignin
ferulates
walls.
Consequently,
varieties
with
reduced
or
ferulate
content
an
altered
composition
can
have
important
beneficial
effects
on
wall
digestibility.
Considerable
efforts
genetic
improvement
been
dedicated
enhancing
digestibility,
benefiting
agriculture,
sector
environment.
In
part
I
paper,
we
review
conventional
advanced
breeding
methods
used
germplasm.
II,
zoom
mutants
improved
digestibility
processing.
Plants,
Год журнала:
2022,
Номер
11(19), С. 2625 - 2625
Опубликована: Окт. 6, 2022
Climate
change
poses
a
serious
threat
to
global
agricultural
activity
and
food
production.
Plant
genome
editing
technologies
have
been
widely
used
develop
crop
varieties
with
superior
qualities
or
can
tolerate
adverse
environmental
conditions.
Unlike
conventional
breeding
techniques
(e.g.,
selective
mutation
breeding),
modern
tools
offer
more
targeted
specific
alterations
of
the
plant
could
significantly
speed
up
progress
developing
crops
desired
traits,
such
as
higher
yield
and/or
stronger
resilience
changing
environment.
In
this
review,
we
discuss
current
development
future
applications
in
mitigating
impacts
biotic
abiotic
stresses
on
agriculture.
We
focus
specifically
CRISPR/Cas
system,
which
has
center
attention
last
few
years
revolutionary
genome-editing
tool
various
species.
also
conducted
bibliographic
analysis
CRISPR-related
papers
published
from
2012
2021
(10
years)
identify
trends
potential
CRISPR/Cas-related
research.
addition,
review
article
outlines
shortcomings
challenges
employing
agriculture
notes
prospective.
believe
combining
innovative
would
be
key
optimizing
improvement
beyond
limitations
traditional
practices.
International Journal of Molecular Sciences,
Год журнала:
2023,
Номер
24(8), С. 7122 - 7122
Опубликована: Апрель 12, 2023
The
biotechnological
approaches
of
transgenesis
and
the
more
recent
eco-friendly
new
breeding
techniques
(NBTs),
in
particular,
genome
editing,
offer
useful
strategies
for
genetic
improvement
crops,
therefore,
recently,
they
have
been
receiving
increasingly
attention.
number
traits
improved
through
editing
technologies
is
growing,
ranging
from
resistance
to
herbicides
insects
capable
coping
with
human
population
growth
climate
change,
such
as
nutritional
quality
or
climatic
stress
diseases.
Research
on
both
has
reached
an
advanced
stage
development
and,
many
biotech
phenotypic
evaluations
open
field
are
already
underway.
In
addition,
approvals
regarding
main
crops
granted.
Over
time,
there
increase
areas
cultivated
that
approaches,
but
their
use
various
countries
limited
by
legislative
restrictions
according
different
regulations
applied
which
affect
cultivation,
marketing,
animal
nutrition.
absence
specific
legislation,
on-going
public
debate
favorable
unfavorable
positions.
This
review
offers
updated
in-depth
discussion
these
issues.
Advances in Agriculture,
Год журнала:
2025,
Номер
2025(1)
Опубликована: Янв. 1, 2025
To
address
the
food
security
of
Ethiopia’s
fast‐growing
population,
transforming
agriculture
to
Agriculture
4.0
is
paramount
by
integrating
emerging
technologies
such
as
remote
sensing,
big
data,
and
artificial
intelligence.
This
review
explores
its
components,
benefits,
challenges,
opportunities
in
Ethiopia
employing
deductive
reasoning
through
a
literature
review.
The
findings
indicated
that
could
optimize
resources,
reduce
production
costs,
provide
real‐time
information,
allow
farmers
draw
well‐informed
judgments.
It
contribute
sustainability
increasing
yield,
productivity,
quality,
reducing
waste,
enhancing
product
traceability.
also
develops
agri‐tech
companies
create
jobs,
need
for
tech‐driven
professions
allowing
smallholder
compete
larger
markets.
Despite
advantages,
Ethiopia,
availability
scattered
small
landholdings,
limited
farmers’
budgets,
poor
infrastructure,
dependence
on
importation
technologies,
increased
tenure
insecurity,
skill
shortage,
lack
training
can
discourage
implementation
4.0.
However,
2025
digital
climate‐smart
initiative,
introduction
5G
networks
data
centers,
tax
exemption
agricultural
machinery
imports
open
chances
adopting
country.
successfully
implement
it
country,
government
concerned
bodies
should
work
establish
microfinance
subsidies
farmers,
increase
market
access
literacy
rate,
encourage
collaboration,
invest
rural
infrastructure.
As
result,
improve
security,
promote
environmental
sustainability,
more
build
resilient
support
population.
Advanced Functional Materials,
Год журнала:
2023,
Номер
33(46)
Опубликована: Сен. 3, 2023
Abstract
CRISPR/Cas13a
is
a
powerful
genome
editing
system
for
RNA
knockdown
that
holds
enormous
potential
cancer
treatment
by
targeting
currently
undruggable
oncogenes
or
immune
checkpoints.
However,
the
precise
intratumoral
activation
of
to
maximize
therapeutic
efficiency
while
guaranteeing
biosafety
remains
daunting
challenge.
Here,
cascade
self‐uncloaking
nanoassembly
(SRC)
based
on
dual‐prodrug
comprising
SN38
and
Cas13a/RNP
developed,
external
encapsulation
performed
coating
with
ROS‐responsive
probe,
which
stimulated
tumor
microenvironment
achieve
efficient
NIR‐II
imaging
CH10055
due
disaggregation
into
single
molecules,
second
release
prodrug
in
hypoxic
environment
enables
targeted
controlled
release.
not
only
induces
immunogenic
cell
death
(ICD),
but
significantly
combats
immunosuppressive
colorectal
combination
novel
checkpoint
TIM3
regulate
cGAS‐STING
pathways,
resulting
synergistic
both
innate
adaptive
immunity.
The
SRC
exhibits
tenfold
increase
regression
α
‐PD‐L1
PD‐L1‐resistant
orthotopic
xenograft
models
inducing
effective
infiltration.
These
results
demonstrate
feasibility
using
treatment,
immense
promise
as
neoadjuvant
strategy
enhancing
CRC
immunotherapy.
