International Journal of Molecular Sciences,
Год журнала:
2025,
Номер
26(7), С. 2970 - 2970
Опубликована: Март 25, 2025
Chaga
(Inonotus
obliquus)
is
an
increasingly
used
natural
product
in
botanical
dietary
supplements,
valued
for
its
bioactive
compounds.
However,
inconsistent
standardized
analytical
methods
raise
concerns
over
authenticity,
mislabeling,
and
quality
control.
This
study
employs
a
multi-analytical
approach
to
differentiate
wildcrafted
chaga
canker
from
North
American
particularly
those
containing
mycelia
fermented
grain
products.
High-Performance
Thin-Layer
Chromatography
(HPTLC),
Liquid
with
Evaporative
Light
Scattering
Detection
(LC-ELSD)
or
Photo/Diode
Array
(LC-PDA/DAD),
Chromatography-Quadrupole
Time-of-Flight
Mass
Spectrometry
(LC-QToF-MS),
Nuclear
Magnetic
Resonance
(NMR)
spectroscopy,
UV-Vis
spectrophotometry,
iodine-starch
assays
were
evaluate
key
markers,
including
triterpenoids,
polysaccharides,
melanin.
Whole
contained
triterpenoids
(inotodiol,
trametenolic
acid)
phenolics,
like
osmundacetone,
while
melanin
absorbance
at
500
nm
differentiated
it
β-Glucan
quantification
confirmed
starch-rich
composition
grains
absence
authentic
canker.
NMR
fingerprinting
LC-QToF-MS
metabolomics
demonstrated
stark
compositional
deviations
between
canker,
I.
obliquus
mycelium,
By
integrating
complementary
techniques,
we
establish
framework
that
can
reliably
distinguish
genuine
misrepresented
products,
ensuring
consumer
safety
fostering
trust
the
functional
mushroom,
mycelium
markets.
Frontiers in Nutrition,
Год журнала:
2022,
Номер
9
Опубликована: Дек. 6, 2022
The
potential
of
edible
mushrooms
as
an
unexploited
treasure
trove,
although
rarely
included
in
known
food
guidelines,
is
highlighted.
Their
role
shielding
people
against
the
side
effects
unhealthy
stylish
diet
reviewed.
Mushrooms
complement
human
with
various
bioactive
molecules
not
identified
or
deficient
foodstuffs
plant
and
animal
sources,
being
considered
a
functional
for
prevention
several
diseases.
have
been
widely
used
medicinal
products
more
than
2,000
years,
but
globally
field
use
wild
has
untapped.
There
broad
range
which
remain
poorly
even
unreported
valuable
pool
sources
compounds
biopharma
utilization
new
dietary
supplements.
Some
unique
elements
their
preventative
healthcare
are
emphasized,
through
positive
impact
on
immune
system.
antiviral,
anti-inflammatory,
anti-neoplastic,
other
health
concerns
discussed.
incorporate
top
non-digestible
oligosaccharides,
ergothioneine,
humans
unable
to
synthesize,
later
antioxidant,
cytoprotective,
anti-inflammatory
element,
therapeutic
potential,
approved
by
world
agencies.
prebiotic
activity
beneficially
affects
gut
homeostasis
performance
balance
microbiota
enhanced.
Several
recent
studies
neurological
contribution
growth
nerve
brain
cells
mentioned.
Indeed,
foods'
nutraceuticals
presently
regarded
next-generation
foods,
supporting
wellness,
promising
prophylactic
agents.
Molecules,
Год журнала:
2023,
Номер
28(14), С. 5393 - 5393
Опубликована: Июль 14, 2023
Medicinal
mushrooms,
e.g.,
Lion’s
Mane
(Hericium
erinaceus
(Bull.)
Pers.),
Reishi
(Ganoderma
lucidum
(Curtis)
P.
Karst.),
Chaga
(Inonotus
obliquus
(Ach.
ex
Pers.)
Pilát),
Cordyceps
(Ophiocordyceps
sinensis
(Berk.)
G.H.
Sung,
J.M.
Hywel-Jones
and
Spatafora),
Shiitake
(Lentinula
edodes
Pegler),
Turkey
Tail
(Trametes
versicolor
(L.)
Lloyd),
are
considered
new-generation
foods
of
growing
interest
to
consumers.
They
characterised
by
a
high
content
biologically
active
compounds,
including
(1,3)(1,6)-β-d-glucans,
which
classified
as
dietary
fibre,
triterpenes,
phenolic
sterols.
Thanks
their
low-fat
content,
they
low-calorie
product
functional
food.
have
beneficial
effect
on
the
organism
through
improvement
its
overall
health
nutritional
level.
The
constituents
contained
in
medicinal
mushrooms
exhibit
anticancer,
antioxidant,
antidiabetic,
immunomodulatory
effects.
In
addition,
these
accelerate
metabolism,
help
fight
obesity,
slow
down
ageing
processes
thanks
antioxidant
activity.
vast
therapeutic
properties
still
not
fully
understood.
Detailed
mechanisms
effects
human
require
long-term
clinical
studies
confirm
nutraceutical
effects,
safety
use,
dosage.
great
potential
be
used
design
innovative
foods.
There
is
need
for
further
research
possibility
incorporating
into
food
products
assess
interactions
bioactive
substances
with
ingredients
matrix.
This
review
focuses
selected
presents
current
knowledge
possibilities
use
production
Heliyon,
Год журнала:
2022,
Номер
8(12), С. e12093 - e12093
Опубликована: Дек. 1, 2022
The
purpose
of
this
review
is
to
provide
information
on
the
nutritional
value
mushrooms
and
how
preserve
that
quality
after
harvest.
Mushrooms
contain
a
variety
vitamins
minerals,
including
B,
C,
D,
are
low
in
calories
high
fiber
(iron,
phosphorus,
copper,
potassium
selenium).
Consuming
may
help
prevent
or
treat
serious
health
conditions
like
cancer,
diabetes,
cardiac
diseases.
protein
cholesterol.
After
being
harvested,
mushrooms'
continues
deteriorate,
showing
signs
discoloration,
moisture
loss,
texture
changes,
an
increase
number
microorganisms,
nutrient
flavor
loss.
Maintaining
postharvest
extending
shelf
life
requires
preservation
techniques,
such
as
physical,
chemical,
thermal
processes.
To
its
during
post-harvest,
there
steps
must
be
taken,
precooling
refrigeration,
washing
with
hydrogen
peroxide,
citric
acid,
sodium
erythorbate,
calcium
chloride,
edible
coating
Aloe
vera,
apple
peel
powder,
carboxymethyl
cellulose,
lecithin,
tartaric
modified
atmosphere
packages,
use
high-quality
packaging
materials
polypropylene.
can
kept
fresher
for
longer
by
steeping
canning.
Researchers,
farmers,
academics
interested
mushroom
cultivation
product
diversification
could
benefit
from
review.
International Journal of Biological Macromolecules,
Год журнала:
2022,
Номер
214, С. 312 - 323
Опубликована: Июнь 14, 2022
Type
2
diabetes
mellitus
is
a
global
disease
that
endangers
human
health,
and
the
need
for
development
of
nontoxic
treatment
candidates
urgent.
In
present
work,
one
homogeneous
polysaccharide
from
Inonotus
obliquus
(IN)
was
isolated,
protective
effect
mechanism
IN
on
type
were
investigated
aspects
intestinal
barrier.
mainly
consisted
9
monosaccharides
with
Mw
373
kDa.
attenuated
body
weight
loss,
alleviated
pathological
damage,
suppressed
production
proinflammatory
cytokines.
Additionally,
repaired
barrier
by
upregulating
expression
Ki-67,
ZO-1
MUC2.
Furthermore,
abundance
Firmicutes
significantly
increased
treatment,
while
levels
Bacteroidetes
inhibited.
conclusion,
protected
against
ameliorating
dysfunction
might
serve
as
novel
drug
candidate
mellitus.
Applied Sciences,
Год журнала:
2022,
Номер
12(22), С. 11426 - 11426
Опубликована: Ноя. 10, 2022
Vast
quantities
of
side
streams
produced
worldwide
by
the
agricultural
and
food
industry
present
an
environmental
challenge
opportunity
for
waste
upcycling
in
frame
circular
bioeconomy.
Fungi
are
capable
transforming
lignocellulosic
residues
wastes
into
a
variety
added-value
compounds
with
applications
functional
products,
pharmaceuticals,
chemicals,
enzymes,
proteins,
emerging
sector
nutraceuticals.
The
liquid
state
culture
fungi
is
efficient
potentially
scalable
reproducible
biotechnological
tool
that
allows
optimized
production
fungal
metabolites.
Particularly,
utilization
agro-industrial
by-products,
residues,
as
substrate
macrofungi
suggested
attainable
solution
management
these
streams,
contributing
to
climate
change
mitigation.
This
review
presents
recently
published
literature
field
cultures
using
different
substrates,
methods,
factors
affecting
their
growth
metabolite
production,
well
applications,
focusing
on
natural
valuable
produced.
PeerJ,
Год журнала:
2023,
Номер
11, С. e15329 - e15329
Опубликована: Май 9, 2023
Garcinia
mangostana
L.
(Mangosteen),
a
functional
food,
belongs
to
the
Garcinaceae
family
and
has
various
pharmacological
effects,
including
anti-oxidative,
anti-inflammatory,
anticancer,
antidiabetic,
neuroprotective
effects.
Mangosteen
abundant
chemical
constituents
with
powerful
After
searching
scientific
literature
databases,
PubMed,
Science
Direct,
Research
Gate,
Web
of
Science,
VIP,
Wanfang,
CNKI,
we
summarized
traditional
applications,
botanical
features,
composition,
effects
mangosteen.
Further,
revealed
mechanism
by
which
it
improves
health
treats
disease.
These
findings
provide
theoretical
basis
for
mangosteen's
future
clinical
use
will
aid
doctors
researchers
who
investigate
biological
activity
functions
food.
Frontiers in Nutrition,
Год журнала:
2024,
Номер
11
Опубликована: Март 20, 2024
Shiitake
mushrooms
are
renowned
for
their
popularity
and
robust
nutritional
value,
susceptible
to
spoilage
due
inherent
biodegradability.
Nevertheless,
because
of
lack
protection,
these
have
a
short
shelf
life.
Throughout
the
post-harvest
phase,
experience
persistent
decline
in
quality.
This
is
evidenced
by
changes
such
as
discoloration,
reduced
moisture
content,
texture
changes,
an
increase
microbial
count,
depletion
nutrients
flavor.
Ensuring
postharvest
quality
preservation
prolonging
mushroom
life
necessitates
utilization
techniques,
including
physical,
chemical,
thermal
processes.
review
provides
comprehensive
overview
deterioration
processes
affecting
quality,
covering
elements
loss,
alterations,
increased
It
also
explores
key
factors
influencing
processes,
temperature,
relative
humidity,
water
activity,
respiration
rate.
Furthermore,
delves
into
recent
progress
preserving
through
techniques
drying,
cooling,
packaging,
irradiation,
washing,
coating.
Journal of Veterinary Medical Science,
Год журнала:
2025,
Номер
87(2), С. 232 - 240
Опубликована: Янв. 1, 2025
Muscle-invasive
bladder
cancer
(MIBC)
is
a
common
form
of
BC
in
dogs.
Adjuvant
chemotherapy
administration
commonly
applied
MIBC
cases,
but
patients
sometimes
experience
treatment
failure
and
recurrence.
Therefore,
supplements
with
anticancer
properties,
such
as
traditional
Chinese
medicines
(TCMs),
are
required,
they
have
been
widely
used
Japanese
human
medicine
may
be
useful
veterinary
medicine.
Furthermore,
organoid
cultures
can
mimic
the
characteristics
their
original
tissues,
self-renewal
organization.
We
previously
established
novel
experimental
model
for
using
dog
(DBCO)
culture.
Herein,
we
examined
antiproliferative
effects
mechanisms
39
substances,
consisting
TCMs,
TCM
supplements,
crude
drug
extracts,
on
DBCOs.
Among
D3
(also
known
Shibe-ria),
which
mixture
chaga
(Inonotus
obliquus)
notoginseng
(Panax
notoginseng),
significantly
diminished
cell
viability
The
expression
stem
markers,
CD44
SOX2,
was
reduced
considerably
D3-treated
components
D3,
exerted
an
effect
DBCO,
whereas
did
not.
also
volume
DBCO
xenografted
tumors
mice
vivo.
Overall,
benefits
natural
supplement
