Recent
advances
in
the
development
of
strategies
for
chemical
adaptation
biomacromolecules,
such
as
polysaccharides,
proteins,
and
lipids,
have
allowed
design
functional
hydrogels
suitable
current
requirements
biomedical
health
care
fields.
Hydrogels
are
three-dimensional
hydrophilic
materials
that
ability
to
absorb
retain
a
large
volume
water
produced
using
lower
fraction
precursor
macromolecules.
They
can
be
made
from
both
natural
synthetic
different
degrees
stiffness
elasticity,
depending
on
projected
application.
biocompatible,
therefore
safely
used
various
applications,
including
contact
lenses,
dressings,
medical
devices,
tissue
engineering
scaffolds.
Also,
they
effective
targeted
delivery
systems
drugs
antibiotics,
analgesics,
chemotherapeutics.
Due
protection
effect
with
regards
high
temperatures,
acidic
environments
enzymatic
degradation
which
affect
wide
range
unstable
macromolecules,
peptides
considered
promising
vehicles.
designed
adaptable
extracellular
matrices,
rigidity
porosity.
functionalized
variety
bioactive
molecules,
growth
factors,
peptides,
very
useful
cartilage
bone
regeneration,
neural
engineering,
wound
healing.
As
anti-aging
therapy
systems,
combined
plant
extracts
or
include
multitude
compounds,
collagen,
hyaluronic
acid,
vitamins,
enzymes,
amino
acids,
probiotics.
The
versatility
unique
properties
bio-hydrogels
challenging
determine
their
study
application
many
fields,
solutions.
aim
this
research
is
provide
an
insight
regarding
status
polysaccharide-based
applications
domain.
This
will
highlight
new
develop
novel
biomaterials
might
help
improving
human
health.
Aloe
vera-based
hydrogels
have
emerged
as
promising
platforms
for
the
delivery
of
therapeutic
agents
in
wound
dressings
due
to
their
biocompatibility
and
unique
wound-healing
properties.
The
present
study
provides
a
comprehensive
overview
recent
advances
application
healing.
synthesis
methods,
structural
characteristics,
properties
are
discussed.
Mechanisms
released
from
hydrogels,
including
diffusion,
swelling,
degradation,
also
analyzed.
In
addition,
effects
on
healing,
well
reduction
inflammation,
antimicrobial
activity,
tissue
regeneration,
highlighted.
incorporation
various
agents,
such
anti-inflammatory
ones,
into
is
reviewed
detail.
Furthermore,
challenges
future
prospects
dressing
applications
considered.
This
review
valuable
information
current
status
highlights
potential
improve
healing
outcomes.
Processes,
Год журнала:
2023,
Номер
11(9), С. 2696 - 2696
Опубликована: Сен. 8, 2023
Biomaterials
are
mostly
any
natural
and
synthetic
materials
which
compatible
from
a
biological
point
of
view
with
the
human
body.
widely
used
to
sustain,
increase,
reestablish
or
substitute
function
injured
tissue
organ
Additionally,
biomaterials
uninterruptedly
in
contact
body,
i.e.,
tissue,
blood
fluids.
For
this
reason,
an
essential
feature
is
their
biocompatibility.
Consequently,
review
summarizes
classification
different
types
based
on
origin,
as
ones.
Moreover,
advanced
applications
pharmaceutical
medical
domains
highlighted
specific
mechanical
physical
properties
biomaterials,
concerning
use.
The
high-priority
challenges
field
also
discussed,
especially
those
regarding
transfer
implementation
valuable
scientific
results
practice.
Gels,
Год журнала:
2024,
Номер
10(9), С. 547 - 547
Опубликована: Авг. 23, 2024
Regenerative
hydrogels
from
natural
polymers
have
come
forth
as
auspicious
materials
for
use
in
regenerative
medicine,
with
interest
attributed
to
their
intrinsic
biodegradability,
biocompatibility,
and
ability
reassemble
the
extracellular
matrix.
This
review
covers
latest
advances
used
wound
healing,
focusing
on
chemical
composition,
cross-linking
mechanisms,
functional
properties.
Key
carbohydrate
polymers,
including
alginate,
chitosan,
hyaluronic
acid,
polysaccharide
gums,
agarose,
carrageenan,
xanthan
gum,
are
discussed
terms
of
sources,
structures
specific
properties
suitable
applications.
The
further
explores
categorization
based
ionic
charge,
response
physiological
stimuli
(i.e.,
pH,
temperature)
particularized
roles
tissue
self-healing.
Various
methods
enhance
mechanical
biological
performance
these
also
examined.
By
highlighting
recent
innovations
ongoing
challenges,
this
article
intends
give
a
detailed
understanding
potential
revolutionize
medicine
improve
patient
healing
outcomes.
IntechOpen eBooks,
Год журнала:
2024,
Номер
unknown
Опубликована: Май 23, 2024
Conventional
therapeutic
models
based
on
the
premise
of
a
universal
solution
are
facing
decrease
in
efficiency,
emphasized
by
large
number
patients
who
show
resistance
or
do
not
respond
positively
to
classic
treatments.
This
perspective
highlights
urgency
for
more
precise
approaches
personalized
treatments
that
adaptable
specific
complexities
and
unique
challenges
faced
each
patient.
Hydrogels
biocompatible
biodegradable
systems
well-controlled
targeted
administration
agents,
being
formed
3D
reticulated
networks
water-soluble
polymeric
biomaterials,
natural,
synthetic,
hybrid
origin,
with
intrinsic
extrinsic
properties.
Due
easily
adjustable
porous
structure,
hydrogels
allow
encapsulation
macromolecular
drugs,
proteins,
small
molecules,
cells,
hormones,
growth
factors
gel
matrix
their
subsequent
controlled
release.
The
biomaterials
used,
crosslinking
methods,
design,
functionalization
strategies
obtaining
improved
properties
presented.
different
possibilities
application
described
transdermally,
as
dressing
materials,
oral,
ocular,
spray-able,
injectable,
up
intracellular
level.
chapter
extensively
investigates
advances
advantages
enable
effective,
noninvasive,
provide
greater
patient
comfort
wide
range
applications.
Gels,
Год журнала:
2024,
Номер
10(10), С. 636 - 636
Опубликована: Сен. 30, 2024
The
innovative
fusion
of
essential
oils
with
hydrogel
engineering
offers
an
optimistic
perspective
for
the
design
and
development
next-generation
materials
incorporating
natural
bioactive
compounds.
This
review
provides
a
comprehensive
overview
latest
advances
in
use
hydrogels
containing
biomedical,
dental,
cosmetic,
food,
food
packaging,
restoration
cultural
heritage
applications.
Polymeric
sources,
methods
obtaining,
cross-linking
techniques,
functional
properties
are
discussed.
unique
characteristics
polymer
agents
highlighted.
These
include
biocompatibility,
nontoxicity,
effective
antibacterial
activity,
control
sustained
prolonged
release
active
substances,
optimal
porosity,
outstanding
cytocompatibility.
Additionally,
specific
distinctive
explored,
along
their
extraction
encapsulation
methods.
advantages
disadvantages
these
also
We
have
considered
limitations
due
to
volatility,
solubility,
environmental
factors,
stability.
importance
loading
hydrogels,
stability,
biological
activity
is
analyzed.
highlights
through
in-depth
analysis,
recent
innovations,
challenges,
future
prospects
encapsulated
potential
multiple
applications
including
biomedicine,
dentistry,
cosmetics,
conservation.
The
removal
of
pharmaceutical
contaminants
from
wastewater
has
gained
considerable
attention
in
recent
years,
particularly
the
advancements
hydrogel-based
adsorbents
as
a
green
solution
for
their
ease
use,
modification,
biodegradability,
non-toxicity,
environmental
friendliness,
and
cost-effectiveness.
This
study
focuses
on
design
an
efficient
adsorbent
hydrogel
based
1%
chitosan,
40%
polyethylene
glycol
4000
(PEG4000),
4%
xanthan
gum
(referred
to
CPX)
diclofenac
sodium
(DCF)
water.
interaction
between
positively
charged
chitosan
negatively
PEG4000
leads
strengthening
structure.
obtained
CPX
hydrogel,
prepared
by
green,
simple,
easy,
low-cost,
ecological
method,
higher
viscosity
due
three-dimensional
polymer
network
mechanical
stability.
physical,
chemical,
rheological,
pharmacotechnical
parameters
synthesized
were
determined.
Swelling
analysis
demonstrated
that
new
synthetized
is
not
pH-dependent.
reached
adsorption
capacity
(172.41
mg/g)
at
highest
amount
(200
mg)
after
350
min.
In
addition,
kinetics
calculated
using
pseudo
first-order
model
Langmuir
Freundlich
isotherm
parameters.
results
demonstrate
can
be
used
option
remove
DCF
contaminant
wastewater.
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(9), С. 4949 - 4949
Опубликована: Май 1, 2024
Antimicrobial
resistance
(AMR)
poses
an
emanating
threat
to
humanity’s
future.
The
effectiveness
of
commonly
used
antibiotics
against
microbial
infections
is
declining
at
alarming
rate.
As
a
result,
morbidity
and
mortality
rates
are
soaring,
particularly
among
immunocompromised
populations.
Exploring
alternative
solutions,
such
as
medicinal
plants
iodine,
shows
promise
in
combating
resistant
pathogens.
Such
antimicrobials
could
effectively
inhibit
proliferation
through
synergistic
combinations.
In
our
study,
we
prepared
formulation
consisting
Aloe
barbadensis
Miller
(AV),
Thymol,
iodine
(I2),
polyvinylpyrrolidone
(PVP).
Various
analytical
methods
including
SEM/EDS,
UV-vis,
Raman,
FTIR,
XRD
were
carried
out
verify
the
purity,
composition,
morphology
AV-PVP-Thymol-I2.
We
evaluated
inhibitory
effects
this
10
selected
reference
strains
using
impregnated
sterile
discs,
surgical
sutures,
gauze
bandages,
face
masks,
KN95
masks.
antimicrobial
properties
AV-PVP-Thymol-I2
assessed
disc
diffusion
comparison
with
two
common
antibiotics.
25-month-old
exhibited
slightly
lower
zones,
indicating
changes
sustained-iodine-release
reservoir.
Our
findings
confirm
potent
antifungal
antibacterial
agent
strains,
demonstrating
strong
action
on
cotton
These
results
enable
potential
use
promising
wound
spray-on
contact-killing
agent.
