Nano TransMed,
Год журнала:
2024,
Номер
3, С. 100042 - 100042
Опубликована: Июль 11, 2024
Novel
drug
delivery
systems
comprise
sophisticated
technology
merged
into
systems.
These
are
created
with
the
aim
of
addressing
limitations
conventional
For
instance,
inefficient
in
tackling
challenging
human
diseases
such
as
cancer.
thus
formed
materials
to
enhance
permeation
target
cells.
They
improve
patients'
compliance
and
efficacy.
include
self-powered
microelectromechanical
Nanotechnology
is
a
rapidly
growing
promising
field,
especially
system
development
disease
therapy.
often
utilise
nanocarriers
due
their
numerous
advantages.
One
benefits
ability
manipulate
size
surface
functionalisation
achieve
site-specific
targeting.
Many
researchers
have
reported
controlled
targeted
release
profiles.
Nanocarriers
propelled
tissues,
where
entrapped
drugs
released,
prolonging
therapeutic
efficacy
decreasing
undesired
side
effects.
Hence,
these
offer
delivery,
low
toxicity,
high
bioavailability
improved
efficiency.
It
essential
understand
mechanisms
toxicity
order
develop
efficient
safe
This
review
describes
utilisation
novel
also
dwells
on
loading,
targeting
from
nanocarriers.
The
primary
concerns
clinical
applications
potential
presented.
expected
that
this
will
be
helpful
formulation
seeking
solutions
cancer
cardiovascular
diseases.
Frontiers in Aging Neuroscience,
Год журнала:
2024,
Номер
16
Опубликована: Апрель 12, 2024
Neuroinflammation
refers
to
a
highly
complicated
reaction
of
the
central
nervous
system
(CNS)
certain
stimuli
such
as
trauma,
infection,
and
neurodegenerative
diseases.
This
is
cellular
immune
response
whereby
glial
cells
are
activated,
inflammatory
mediators
liberated
reactive
oxygen
nitrogen
species
synthesized.
key
process
that
helps
protect
brain
from
pathogens,
but
inappropriate,
or
protracted
inflammation
yields
pathological
states
Parkinson’s
disease,
Alzheimer’s,
Multiple
Sclerosis,
other
disorders
showcase
various
pathways
neurodegeneration
distributed
in
parts
CNS.
review
reveals
major
neuroinflammatory
signaling
associated
with
neurodegeneration.
Additionally,
it
explores
promising
therapeutic
avenues,
stem
cell
therapy,
genetic
intervention,
nanoparticles,
aiming
regulate
neuroinflammation
potentially
impede
decelerate
advancement
these
conditions.
A
comprehensive
understanding
intricate
connection
between
diseases
pivotal
for
development
future
treatment
strategies
can
alleviate
burden
imposed
by
devastating
disorders.
Abstract
This
review
explores
recent
advancements
and
applications
of
3D
printing
in
healthcare,
with
a
focus
on
personalized
medicine,
tissue
engineering,
medical
device
production.
It
also
assesses
economic,
environmental,
ethical
considerations.
In
our
the
literature,
we
employed
comprehensive
search
strategy,
utilizing
well-known
databases
like
PubMed
Google
Scholar.
Our
chosen
keywords
encompassed
essential
topics,
including
printing,
nanotechnology,
related
areas.
We
first
screened
article
titles
abstracts
then
conducted
detailed
examination
selected
articles
without
imposing
any
date
limitations.
The
for
inclusion,
comprising
research
studies,
clinical
investigations,
expert
opinions,
underwent
meticulous
quality
assessment.
methodology
ensured
incorporation
high-quality
sources,
contributing
to
robust
exploration
role
realm
healthcare.
highlights
printing's
potential
customized
drug
delivery
systems,
patient-specific
implants,
prosthetics,
biofabrication
organs.
These
innovations
have
significantly
improved
patient
outcomes.
Integration
nanotechnology
has
enhanced
precision
biocompatibility.
demonstrates
cost-effectiveness
sustainability
through
optimized
material
usage
recycling.
healthcare
sector
witnessed
remarkable
progress
promoting
patient-centric
approach.
From
implants
radiation
shielding
offers
tailored
solutions.
Its
transformative
applications,
coupled
economic
viability
sustainability,
revolutionize
Addressing
biocompatibility,
standardization,
concerns
is
responsible
adoption.
Graphical
Cancers,
Год журнала:
2024,
Номер
16(6), С. 1156 - 1156
Опубликована: Март 14, 2024
Hyperthermia
(HT)
is
an
anti-cancer
therapy
commonly
used
with
radio
and
chemotherapies
based
on
applying
heat
(39-45
°C)
to
inhibit
tumor
growth.
However,
controlling
towards
tumors
not
normal
tissues
challenging.
Therefore,
nanoparticles
(NPs)
are
in
HT
apply
only
induce
DNA
damage
the
expression
of
shock
proteins,
which
eventually
result
apoptosis.
The
aim
this
review
article
summarize
recent
advancements
use
magnetic
NPs
locally
increase
temperature
promote
cell
death.
In
addition,
development
nanocarriers
as
NP-based
drug
delivery
systems
discussed.
Finally,
efficacy
combined
chemotherapy,
radiotherapy,
gene
therapy,
photothermal
immunotherapy
explored.
Fungal Diversity,
Год журнала:
2024,
Номер
125(1), С. 1 - 71
Опубликована: Март 20, 2024
Abstract
The
field
of
mycology
has
grown
from
an
underappreciated
subset
botany,
to
a
valuable,
modern
scientific
discipline.
As
this
study
grown,
there
have
been
significant
contributions
science,
technology,
and
industry,
highlighting
the
value
fungi
in
era.
This
paper
looks
at
current
research,
along
with
existing
limitations,
suggests
future
areas
where
scientists
can
focus
their
efforts,
mycology.
We
show
how
become
important
emerging
diseases
medical
discuss
trends
potential
drug
novel
compound
discovery.
explore
phylogenomics,
its
potential,
outcomes
address
question
phylogenomics
be
applied
fungal
ecology.
In
addition,
functional
genomics
studies
are
discussed
importance
unravelling
intricate
mechanisms
underlying
behaviour,
interactions,
adaptations,
paving
way
for
comprehensive
understanding
biology.
look
research
building
materials,
they
used
as
carbon
sinks,
biocircular
economies.
numbers
always
great
interest
often
written
about
estimates
varied
greatly.
Thus,
we
needs
order
obtain
more
reliable
estimates.
aspects
machine
learning
(AI)
it
mycological
research.
Plant
pathogens
affecting
food
production
systems
on
global
scale,
such,
needed
area,
particularly
disease
detection.
latest
data
High
Throughput
Sequencing
if
still
gaining
new
knowledge
same
rate
before.
A
review
nanotechnology
is
provided
addressed.
Arbuscular
Mycorrhizal
Fungi
addressed
acknowledged.
Fungal
databases
becoming
important,
therefore
provide
major
databases.
Edible
medicinal
huge
medicines,
especially
Asia
prospects
discussed.
Lifestyle
changes
(e.g.,
endophytes,
pathogens,
and/or
saprobes)
also
extremely
trend
special
issue
Diversity.
Molecules,
Год журнала:
2024,
Номер
29(9), С. 2073 - 2073
Опубликована: Апрель 30, 2024
The
concept
of
nanomedicine
has
evolved
significantly
in
recent
decades,
leveraging
the
unique
phenomenon
known
as
enhanced
permeability
and
retention
(EPR)
effect.
This
facilitated
major
advancements
targeted
drug
delivery,
imaging,
individualized
therapy
through
integration
nanotechnology
principles
into
medicine.
Numerous
nanomedicines
have
been
developed
applied
for
disease
treatment,
with
a
particular
focus
on
cancer
therapy.
Recently,
utilized
various
advanced
fields,
including
diagnosis,
vaccines,
immunotherapy,
gene
tissue
engineering.
Multifunctional
facilitate
concurrent
medication
therapeutic
monitoring,
allowing
immediate
responses
personalized
treatment
plans.
review
concerns
advancement
nanomaterials
their
potential
applications
biological
medical
fields.
Along
this,
we
also
mention
clinical
translations
challenges
that
is
currently
facing
to
overcome
translation
barrier.
Nanomaterials,
Год журнала:
2024,
Номер
14(17), С. 1425 - 1425
Опубликована: Авг. 31, 2024
Silver
nanoparticles
(Ag
NPs)
have
accumulated
significant
interest
due
to
their
exceptional
physicochemical
properties
and
remarkable
applications
in
biomedicine,
electronics,
catalysis
sensing.
This
comprehensive
review
provides
an
in-depth
study
of
synthetic
approaches
such
as
biological
synthesis,
chemical
physical
synthesis
with
a
detailed
overview
sub-methodologies,
highlighting
advantages
disadvantages.
Additionally,
structural
affected
by
methods
are
discussed
detail
examining
the
dimensions
surface
morphology.
The
explores
distinctive
Ag
NPs,
including
optical,
electrical,
catalytic,
antimicrobial
properties,
which
render
them
beneficial
for
range
applications.
Furthermore,
this
describes
diverse
several
fields,
medicine,
environmental
science,
optoelectronics.
However,
numerous
applications,
kinds
issues
still
exist.
Future
attempts
need
address
difficulties
regarding
techniques,
friendliness,
affordability.
In
order
ensure
secure
utilization
it
is
necessary
establish
sustainability
techniques
eco-friendly
production
methods.
aims
give
analysis,
multifaceted
NPs.
International Journal of Nanomedicine,
Год журнала:
2024,
Номер
Volume 19, С. 6099 - 6126
Опубликована: Июнь 1, 2024
Abstract:
The
relentless
pursuit
of
effective
cancer
diagnosis
and
treatment
strategies
has
led
to
the
rapidly
expanding
field
nanotechnology,
with
a
specific
focus
on
nanocomposites.
Nanocomposites,
combination
nanomaterials
diverse
properties,
have
emerged
as
versatile
tools
in
oncology,
offering
multifunctional
platforms
for
targeted
delivery,
imaging,
therapeutic
interventions.
Nanocomposites
exhibit
great
potential
early
detection
accurate
imaging
diagnosis.
Integrating
various
modalities,
such
magnetic
resonance
(MRI),
computed
tomography
(CT),
fluorescence
into
nanocomposites
enables
development
contrast
agents
enhanced
sensitivity
specificity.
Moreover,
functionalizing
targeting
ligands
ensures
selective
accumulation
tumor
tissues,
facilitating
precise
diagnostic
accuracy.
On
front,
revolutionized
by
overcoming
traditional
challenges
associated
drug
delivery.
controlled
release
from
nanocomposite
carriers
enhances
bioavailability,
reduces
systemic
toxicity,
improves
overall
efficacy.
Additionally,
integration
stimuli-responsive
components
within
site-specific
triggered
unique
microenvironment
tumor.
Despite
remarkable
progress
field,
biocompatibility,
scalability,
long-term
safety
profiles
remain.
This
article
provides
comprehensive
overview
recent
developments,
challenges,
prospects,
emphasizing
transformative
revolutionizing
landscape
diagnostics
therapeutics.
In
Conclusion,
integrating
heralds
new
era
precision
medicine.
Keywords:
nanocomposites,
cancer,
diagnosis,
therapy,
nanoparticles,
theranostic
Pharmaceuticals,
Год журнала:
2024,
Номер
17(6), С. 677 - 677
Опубликована: Май 24, 2024
Nanotechnology
has
emerged
as
a
transformative
force
in
oncology,
facilitating
advancements
site-specific
cancer
therapy
and
personalized
oncomedicine.
The
development
of
nanomedicines
explicitly
targeted
to
cells
represents
pivotal
breakthrough,
allowing
the
precise
interventions.
These
cancer-cell-targeted
operate
within
intricate
milieu
tumour
microenvironment,
further
enhancing
their
therapeutic
efficacy.
This
comprehensive
review
provides
contemporary
perspective
on
precision
medicine
underscores
critical
role
nanotechnology
advancing
It
explores
categorization
nanoparticle
types,
distinguishing
between
organic
inorganic
variants,
examines
significance
delivery
anticancer
drugs.
Current
insights
into
strategies
for
developing
actively
across
various
types
are
also
provided,
thus
addressing
relevant
challenges
associated
with
drug
barriers.
Promising
future
directions
nanomedicine
approaches
delivered,
emphasising
imperative
continued
optimization
nanocarriers
medicine.
discussion
translational
research’s
need
enhance
patients’
outcomes
by
refining
nanocarrier
technologies
nanotechnology-driven,
therapy.
