Zinc and melatonin mediated antimicrobial, anti-inflammatory, and antioxidant coatings accelerate bone defect repair
Fengzhen Jia,
Jiaxin Guan,
Jiali Wang
и другие.
Colloids and Surfaces B Biointerfaces,
Год журнала:
2024,
Номер
unknown, С. 114335 - 114335
Опубликована: Окт. 1, 2024
Язык: Английский
Emerging Trends in Smart Self-Healing Coatings: A Focus on Micro/Nanocontainer Technologies for Enhanced Corrosion Protection
Coatings,
Год журнала:
2024,
Номер
14(3), С. 324 - 324
Опубликована: Март 8, 2024
Smart
self-healing
coatings
offer
a
revolutionary
approach
to
mitigating
metal
corrosion,
problem
with
significant
economic
and
environmental
impacts.
Divided
into
intrinsic
extrinsic
types,
these
autonomously
rectify
the
damage.
Intrinsic
variants
utilize
reversible
bonds
achieve
ongoing
repair,
while
ones
incorporate
micro/nanocontainers
that
activate
upon
triggers
mend
micro-cracks,
their
efficacy
dictated
by
encapsulated
healing
agents’
volume.
This
review
dissects
rapidly
evolving
sector
of
stimuli-responsive
coatings,
emphasizing
progress
in
micro/nano
container
technology.
It
discusses
synthesis
encapsulation
processes
different
charts
transition
from
single
multistimulus-responsive
systems,
which
enhances
coatings’
sensitivity
functionality.
The
addition
multifunctional
traits
such
as
self-reporting
anti-microbial
actions
further
broadens
industrial
applicability.
provides
succinct
overview
field’s
current
state
future
potential,
envisioning
paradigm
shift
corrosion
protection
through
advanced
smart
coatings.
Язык: Английский
Smart responsive in situ hydrogel systems applied in bone tissue engineering
Shunli Wu,
Tingting Gai,
Jie Chen
и другие.
Frontiers in Bioengineering and Biotechnology,
Год журнала:
2024,
Номер
12
Опубликована: Май 28, 2024
The
repair
of
irregular
bone
tissue
suffers
severe
clinical
problems
due
to
the
scarcity
an
appropriate
therapeutic
carrier
that
can
match
dynamic
and
complex
damage.
Fortunately,
stimuli-responsive
in
situ
hydrogel
systems
are
triggered
by
a
special
microenvironment
could
be
ideal
method
regenerating
because
injectability,
gelatin,
spatiotemporally
tunable
drug
release.
Herein,
we
introduce
two
main
stimulus-response
approaches,
exogenous
endogenous,
forming
hydrogels
engineering.
First,
summarize
specific
distinct
responses
extensive
range
external
stimuli
(e.g.,
ultraviolet,
near-infrared,
ultrasound,
etc.)
form
created
from
biocompatible
materials
modified
various
functional
groups
or
hybrid
nanoparticles.
Furthermore,
“smart”
hydrogels,
which
respond
endogenous
physiological
environmental
temperature,
pH,
enzyme,
etc.),
achieve
gelation
one
injection
vivo
without
additional
intervention.
Moreover,
mild
chemistry
response-mediated
also
offer
fascinating
prospects
engineering,
such
as
Diels–Alder,
Michael
addition,
thiol-Michael
Schiff
reactions,
etc.
recent
developments
challenges
smart
their
application
administration
engineering
discussed
this
review.
It
is
anticipated
advanced
strategies
innovative
ideas
will
exploited
field
increase
quality
life
for
patients
with
Язык: Английский
Multifunctional hydrogel scaffolds based on polysaccharides and polymer matrices promote bone repair: A review
International Journal of Biological Macromolecules,
Год журнала:
2025,
Номер
294, С. 139418 - 139418
Опубликована: Янв. 5, 2025
Язык: Английский
Mineral nanoparticles and nanocomposite hydrogels with osteoinductive properties for bone regeneration
Опубликована: Март 17, 2025
Mineral
nanoparticles
and
osteoinductive
biomaterials
are
essential
in
advancing
bone
regeneration
by
addressing
skeletal
conditions
injuries
that
compromise
structural
integrity
functionality.
These
stimulate
the
differentiation
of
precursor
cells
into
osteoblasts,
creating
biocompatible
environments
conducive
to
tissue
regeneration.
Among
most
promising
innovations,
mineral-based
nanocomposite
hydrogels
have
emerged
as
effective
strategies
for
enhancing
potential.
This
review
explores
diverse
types
biomaterials,
including
natural
sources,
synthetic
compounds,
hybrid
designs
incorporate
mineralized
nanoparticles.
Emphasis
is
placed
on
polymeric
delivery
platforms
these
materials,
highlighting
their
dual
role
supports
bioactive
agents
promote
osteogenesis.
Challenges
such
immune
rejection,
biodegradability,
mechanical
stability,
short
vivo
residence
time
critically
discussed,
alongside
impact
clinical
translation.
By
presenting
a
comprehensive
analysis
mechanisms,
applications,
limitations,
this
identifies
opportunities
integrating
with
emerging
fields
like
immunology
biomechanics.
Ultimately,
work
aims
provide
actionable
insights
advance
development
novel,
clinically
relevant
solutions
improve
patient
outcomes
address
growing
global
need
repair
Язык: Английский
“Disguise strategy” to bacteria: A multifunctional hydrogel with bacteria-targeting and photothermal conversion properties for the repair of infectious bone defects
Bioactive Materials,
Год журнала:
2025,
Номер
47, С. 343 - 360
Опубликована: Фев. 12, 2025
Язык: Английский
Preparations of P(Acrylamido-2-methylpropane sulfonic acid-co-N,N′-dimethylacrylamide)/P(Acrylamide-co-acrylic acid) tough double network hydrogels as a carrier toward antibacterial applications
Materials Today Chemistry,
Год журнала:
2025,
Номер
44, С. 102591 - 102591
Опубликована: Фев. 15, 2025
Язык: Английский
Advances of novel hydrogels in the healing process of alveolar sockets
Biomaterials Advances,
Год журнала:
2025,
Номер
173, С. 214280 - 214280
Опубликована: Март 9, 2025
Язык: Английский
Icariin-Enhanced Osteoclast-Derived Exosomes Promote Repair of Infected Bone Defects by Regulating Osteoclast and Osteoblast Communication
International Journal of Nanomedicine,
Год журнала:
2024,
Номер
Volume 19, С. 12389 - 12407
Опубликована: Ноя. 1, 2024
Infected
bone
defects
pose
a
challenging
clinical
issue
due
to
an
imbalance
of
osteoclasts
(OC)
and
osteoblasts
(OB).
Exosomes
are
crucial
for
intercellular
signaling
OC
OB
in
repair.
Icariin,
has
been
shown
regulate
the
balance
between
OB.
However,
specific
mechanisms
by
which
icariin
influences
exosomes
derived
from
osteoclasts,
subsequently
impacts
osteoblast
activity,
remain
unclear.
This
study
aims
investigate
effects
icariin-treated
osteoclast-derived
(ICA-OC-Exo)
on
function
repair
cases
infected
defects.
Язык: Английский