Heliyon, Год журнала: 2024, Номер 10(23), С. e40589 - e40589
Опубликована: Ноя. 21, 2024
Язык: Английский
Journal of Food Processing and Preservation, Год журнала: 2025, Номер 2025(1)
Опубликована: Янв. 1, 2025
Peptide size is a key factor influencing their biological activity. Taking advantage of this relationship, ultrafiltration (UF) emerges as valuable tool for fractionating complex peptide mixtures obtained from natural sources. Recent studies have focused on the application technology to legumes and oilseeds, with aim identifying fractions bioactive potential. The study aimed at evaluating in vitro hypocholesterolemic antidiabetic activity protein hydrolysate sunflower ( Helianthus annuus ) seeds. results showed that highest degree hydrolysis values was 120 min both enzymes: alcalase flavourzyme 70.06% 38.75%, respectively. Protein hydrolysates UF membrane process helped obtain low molecular weight such 1–3 kDa fraction greater 79% enzymes (alcalase flavourzyme), while higher < 1 80 100 reaction 55.65% 70.18% inhibition α ‐amylase. best value ‐glucosidase 34.73% 46.02% > 5 20 min. allowed obtaining different weights activity, which could be an alternative design development nutraceutical products treatment chronic degenerative diseases.
Язык: Английский
Процитировано
2
Journal of Food Biochemistry, Год журнала: 2024, Номер 2024, С. 1 - 21
Опубликована: Янв. 5, 2024
Plants could be used for multiple medicinal purposes. Moringa oleifera (MO) is considered the most famous plant this purpose. The present review aimed to spot light on recent medicinal, biochemical, and nutritional applications of MO. contains a huge number nutrients such as fatty acids, amino proteins, polysaccharides, minerals, vitamins. It has been control glucose, lipids, vitamins, hormones, antioxidants in many animals human models. Its are also varied wide; it manage lots disorders. Extracts isolated ingredients from open way researchers all over world study its biochemical impact experimental clinical spots significance MO opening discussion demonstrating strengths weaknesses research area. Regardless contrary concept, we promising that studied both molecular levels. We recommended further effects healthy diseased
Язык: Английский
Процитировано
9
Elsevier eBooks, Год журнала: 2024, Номер unknown, С. 305 - 325
Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
4
Frontiers in Microbiology, Год журнала: 2024, Номер 15
Опубликована: Янв. 24, 2024
Introduction Fungal keratitis (FK) poses a severe threat to vision, potentially leading blindness if not promptly addressed. Clitoria ternatea flower extracts have history of use in Ayurvedic and Indian traditional medicines, particularly for treating eye ailments. This study investigates the antifungal antibiofilm effects on FK clinical isolate Coniochaeta hoffmannii . Structural details key compound identification were analysed through FTIR GC-MS. Methods The minimum inhibitory concentration (MIC) fungicidal (MFC) determined using broth dilution well plate techniques. Biofilm activity was assessed microscopic evaluation, while anti-irritant cytotoxic properties evaluated CAE-EI MTT assays. Through GC-MS FT-IR analysis compounds dissolved extract their functional group studied, toxicity screening pharmacokinetic prediction conducted silico Subsequently, with high corneal permeability further identified, molecular docking simulation studies at 150 ns used investigate interactions fungal virulence factors human inflammatory proteins. Results Discussion At 250 µg/mL, displayed effective biofilm inhibition. MIC MFC values as 500 1000 respectively. assays indicated no significant irritant up 3 mg/mL. Compounds like 9,9-dimethoxybicyclo[3.3.1]nonane-2,4-dione showed strong stable cellobiose dehydrogenase, endo β 1,4 xylanase, glucanase, inflammation-associated TNF-α Interleukin IL-1b protein targets. findings indicate that from C. flowers could be formulated an safe alternative developing new topical therapeutics.
Язык: Английский
Процитировано
4
Next research., Год журнала: 2025, Номер unknown, С. 100218 - 100218
Опубликована: Фев. 1, 2025
Язык: Английский
Процитировано
0
Journal of Food Biochemistry, Год журнала: 2024, Номер 2024, С. 1 - 17
Опубликована: Март 21, 2024
The possibility of developing waste by-products food processing into functional additives along with probiotics is an interesting avenue to research. This study investigated the nutritional and attributes dried mango peel powder (MPP) Langra cultivar its putative potential act as a prebiotic in presence two probiotic strains Lacticaseibacillus rhamnosus NCDC347 Limosilactobacillus fermentum NCDC143 @ 2.5 & 5% after 24 48 h fermentation. Proximate analysis revealed that MPP contains 6.45 % moisture, 6.34 protein, 3.88 fat, 2.50 ash, 32.86 crude dietary fiber, 47.97 total carbohydrate content. MP displayed substantial antioxidant 54.6% DPPH inhibitory activity, 15.67 mg GAE/g TPC, 8.88 QuE/g TFC, OHC 1.47 g oil/g, WHC 4.7 water/g. could selectively stimulate growth over enteric bacteria. It was combination @5% L. fermentation had best vitro activity score 3.35 3.53 against Escherichia coli ATCC 25922 Enterococcus faecalis NCDC114, respectively. better than commercial malto-dextrin for all combinations tested. percentage inhibition increased during NCDC143, highlighting role source antioxidants. These findings contribute formulation synbiotic products are able maintain selected healthy microbiota human gut.
Язык: Английский
Процитировано
3
Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
0
Heliyon, Год журнала: 2024, Номер 10(23), С. e40589 - e40589
Опубликована: Ноя. 21, 2024
Язык: Английский
Процитировано
0