Spectral Characteristics, In Silico Perspectives, Density Functional Theory (DFT), and Therapeutic Potential of Green-Extracted Phycocyanin from Spirulina
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(17), С. 9170 - 9170
Опубликована: Авг. 23, 2024
Phycocyanin
(PC)
is
a
naturally
occurring
green
pigment
in
Spirulina.
It
was
extracted
by
ultrasonic
extraction
using
technology,
and
its
structure
studied
IR-
NMR-spectroscopy.
Spectral
data
confirmed
the
PC
structure.
This
study
also
involves
an
silico
assessment
of
diverse
applications
PC.
Utilizing
QSAR,
PreADME/T,
SwissADME,
Pro-Tox,
this
explores
safety
profile,
pharmacokinetics,
potential
targets
QSAR
analysis
reveals
favorable
with
parent
most
metabolites
showing
no
binding
to
DNA
or
proteins.
PreADME/T
indicates
low
skin
permeability,
excellent
intestinal
absorption,
medium
supporting
oral
administration.
Distribution
suggests
moderate
plasma
protein
cautious
blood-brain
barrier
guiding
formulation
strategies.
Metabolism
assessments
highlight
interactions
key
cytochrome
P450
enzymes,
influencing
drug
interactions.
Target
prediction
unveils
targets,
suggesting
therapeutic
effects,
including
cardiovascular
benefits,
anti-inflammatory
activities,
neuroprotection,
immune
modulation.
Based
on
analysis,
holds
promise
for
various
due
safety,
bioavailability,
benefits.
Experimental
validation
crucial
elucidate
precise
molecular
mechanisms,
ensuring
safe
effective
utilization
dietary
contexts.
DFT
calculations,
geometry
optimization,
MEP
HOMO-LUMO
energy
surface,
quantum
reactivity
parameters
compound,
were
obtained
B3LYP/6-311G(d,p)
level.
integrated
approach
contributes
comprehensive
understanding
PC's
pharmacological
profile
informs
future
research
directions.
Язык: Английский
Bioactive Compounds from Spirulina spp.—Nutritional Value, Extraction, and Application in Food Industry
Separations,
Год журнала:
2024,
Номер
11(9), С. 257 - 257
Опубликована: Авг. 30, 2024
The
surging
popularity
of
plant-based
diets
and
the
growing
emphasis
on
clean-label
products
have
intensified
interest
in
Spirulina
within
food
industry.
As
more
people
adopt
vegetarian,
vegan,
or
flexitarian
lifestyles,
demand
for
protein
sources
has
escalated.
Spirulina’s
high
content
complete
amino
acid
profile
make
it
an
ideal
candidate
to
meet
this
demand.
However,
incorporating
into
is
not
without
its
challenges.
Its
strong,
earthy,
fishy
taste
can
be
off-putting
consumers
difficult
mask
formulations.
Furthermore,
isolating
bioactive
compounds
while
preserving
their
integrity
complex,
especially
considering
heat
sensitivity
many
these
components.
Traditional
extraction
methods
often
employ
temperatures,
which
degrade
valuable
compounds.
Consequently,
there
a
preference
non-thermal
techniques.
This
paper
provides
overview
recent
advancements
cultivation,
extraction,
application
products.
Язык: Английский
Optimised Extraction and Purification of Dual-Function Cosmetic-Grade Phycocyanin and Allophycocyanin from Dried Arthrospira platensis Biomass Using Conventional Methods
Applied Sciences,
Год журнала:
2025,
Номер
15(2), С. 532 - 532
Опубликована: Янв. 8, 2025
Arthospira
platensis
is
a
filamentous
cyanobacterium
considered
an
important
source
of
phycobiliproteins
(PBP),
class
water-soluble
pigments
with
wide
range
applications.
Although
several
extraction
and
purification
techniques
PBP
have
been
reported,
there
still
need
for
strategies
that
achieve
balance
between
simplicity,
cost-effectiveness,
scalability.
To
address
this
need,
study
systematically
evaluated
conventional
methods—homogenisation,
freeze–thaw
cycles,
maceration.
Maceration
showed
the
best
yield
purity
recovery
among
tested
techniques,
under
optimal
conditions
(three
2
h/cycle,
0.1
M
phosphate
buffer),
55.9
mg/g
biomass
phycocyanin
(PC)
24.9
allophycocyanin
(APC)
notable
antioxidant
capacity
(Folin-Ciocalteu’s
ABTS●+
assays)
were
yielded.
Among
ammonium
sulphate
fractionation
achieved
2.3
recoveries
92.9%
79.9%
PC
APC,
respectively,
while
0.5%
activated
carbon
resulted
in
extract
2.5
90.9%
87.2%
(APC).
The
suggested
procedures
could
be
fast
cost-effective
way
to
obtain
cosmetic-grade
PBP,
thus
offering
accessible
solution
industries
prioritising
sustainable
economically
viable
production
pipelines.
Язык: Английский
Phycocyanin: A potential bioresource for functional food product development
South African Journal of Botany,
Год журнала:
2024,
Номер
174, С. 49 - 65
Опубликована: Сен. 6, 2024
Язык: Английский
Improved recyclability of Spirulina culture medium through ultrafiltration
Separation and Purification Technology,
Год журнала:
2024,
Номер
354, С. 129168 - 129168
Опубликована: Авг. 12, 2024
Язык: Английский
Optimization of phycobiliprotein extraction from triple algal co-culture
Systems Microbiology and Biomanufacturing,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 13, 2024
Язык: Английский
The blue palette of life: A comprehensive review of natural bluish colorants with potential commercial applications
Food Research International,
Год журнала:
2024,
Номер
196, С. 115082 - 115082
Опубликована: Сен. 23, 2024
Язык: Английский
ALGALELIXIRS: UNRAVELING THE MULTIFACETED IMPACT OF SPIRULINA IN HUMAN HEALTH
Food Bioscience,
Год журнала:
2024,
Номер
unknown, С. 105365 - 105365
Опубликована: Окт. 1, 2024
Язык: Английский
Comparison of Pressurized Water Extraction With Ultrasound Assisted Extraction for Isolation of Phycobiliproteins From Arthrospira platensis (Spirulina)
Phytochemical Analysis,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 10, 2024
Cyanobacterium
Arthrospira
platensis
(AP)
(Nordstedt)
Gomont
contains
high
content
of
phycobiliproteins
(PBP),
which
are
an
important
source
for
food
industry.
Methods
effectively
extracting
proteins
contained
in
AP
cells
demanded
to
provide
a
supply
the
material.
Water-based
extraction
methods
advisable
due
solubility
PBP.
Язык: Английский