
Molecules, Год журнала: 2025, Номер 30(5), С. 1016 - 1016
Опубликована: Фев. 22, 2025
Beta-blockers are pharmaceuticals used to treat cardiovascular diseases such as hypertension, angina pectoris, and arrhythmia. Due high consumption, they continuously released into the environment, being detected in many aqueous matrices. The aim of this research is test effectiveness two green liquid-phase microextraction procedures, dispersive liquid-liquid (DLLME) solidification floating organic droplet (SFOME) for selective extraction eight beta-blockers (atenolol, nadolol, pindolol, acebutolol, metoprolol, bisoprolol, propranolol, betaxolol) from matrices their analysis by gas chromatography (GC) or liquid (LC). influence parameters, type volume disperser solvents, ionic strength were studied. developed procedures provide a good enrichment factor six compounds (61.22-243.97), recovery (53.04-92.1%), sample cleaning both procedures. Good limits detection (0.13 0.69 µg/mL GC 0.07 0.15 HPLC) quantification (0.39 2.10 0.20 0.45 LC) obtained. successfully applied selected wastewater samples, proving applicability real samples.
Язык: Английский