Environmental Science and Pollution Research, Год журнала: 2024, Номер 31(28), С. 40758 - 40777
Опубликована: Май 31, 2024
Язык: Английский
Frontiers in Endocrinology, Год журнала: 2024, Номер 14
Опубликована: Янв. 17, 2024
Reproductive system diseases pose prominent threats to human physical and mental well-being. Besides being influenced by genetic material regulation changes in lifestyle, the occurrence of these is closely connected exposure harmful substances environment. Endocrine disrupting chemicals (EDCs), characterized hormone-like effects, have a wide range influences on reproductive system. EDCs are ubiquitous natural environment present industrial everyday products. Currently, thousands been reported exhibit endocrine this number likely increase as testing for potential has not consistently required, obtaining data limited, partly due long latency many diseases. The ability avoid EDCs, especially those artificially synthesized origin, increasingly challenging. While can be divided into persistent non-persistent depending their degree degradation, recent uptick research studies area, we chosen focus pertaining detrimental effects health several that widely encountered daily life over past six years, specifically bisphenol A (BPA), phthalates (PAEs), polychlorinated biphenyls (PCBs), parabens, pesticides, heavy metals, so on. By focusing impact hypothalamic-pituitary-gonadal (HPG) axis, which leads development diseases, review aims provide new insights molecular mechanisms EDCs’ damage encourage further in-depth clarify potentially EDC through various other mechanisms. Ultimately, it offers scientific basis enhance risk management, an endeavor significant societal importance safeguarding health.
Язык: Английский
Процитировано
36
Reproductive Toxicology, Год журнала: 2025, Номер 132, С. 108861 - 108861
Опубликована: Фев. 13, 2025
Язык: Английский
Процитировано
1
Critical Reviews in Analytical Chemistry, Год журнала: 2024, Номер unknown, С. 1 - 18
Опубликована: Март 7, 2024
The number of pollutants and chemicals with the potential to reach environment is still largely unknown, which poses great challenges for researchers in various fields science, environmental scientists, analytical chemists. Chromatographic techniques, both gas chromatography (GC) liquid (LC) coupled different types detection, are now invaluable tools identification a wide range chemical compounds contaminants water. This review devoted chromatographic techniques GC-MS, GC-Orbitrap-MS, GC-MS/MS, GC-HRMS, GC × GC-TOFMS, GC-ECD, LC-MS/MS, HPLC-UV, HPLC-PDA, UPLC-QTOFMS, used determinate emerging organic aquatic media, mainly urban water, published scientific literature over past several years. article also focuses on sample preparation methods analysis aqueous samples. Most research minimizing steps, reducing amount solvents used, speed analysis, ability apply it analytes sample. extremely important application sensitive selective monitor status water quality assess its impact human health.
Язык: Английский
Процитировано
6
The Science of The Total Environment, Год журнала: 2025, Номер 963, С. 178434 - 178434
Опубликована: Янв. 17, 2025
Язык: Английский
Процитировано
0
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0
Environment & Health, Год журнала: 2024, Номер 3(2), С. 164 - 176
Опубликована: Ноя. 3, 2024
Characterizing the chemical composition of semen can provide valuable insights into exposome and environmental factors that directly affect seminal overall health. In this study, we compared molecular profiles 45 donated samples from general population New York City participants examined correlation between in fertility parameters, i.e., sperm concentration, motility, morphology, volume. Samples were prepared using a protein precipitation procedure analyzed liquid chromatography (LC) coupled to high-resolution mass spectrometry (HRMS). Non-targeted analysis (NTA) revealed 18 chemicals not previously reported human studies, with 3-hydroxyoctanedioic acid, cosmetic additive, emerging as plausible candidate found be at higher levels cases vs controls (p < 0.01) associated adverse motility morphology. Four level 1 identified compounds have associations health parameters; dibutyl phthalate 2-aminophenol negatively impacted 4-nitrophenol was low while palmitic acid both morphology This study aims utilize NTA understand association contaminants concern (CECs) along full profile find trends separating poor normal parameters each other chemically. Our results suggest collective effects many CECs could adversely quality.
Язык: Английский
Процитировано
2
Опубликована: Сен. 2, 2024
Characterizing chemical composition of semen can provide valuable insights into the exposome and environmental factors that directly affect seminal overall health. In this study, we compared molecular profiles 45 donated samples from general population New York City participants examined correlation between in vs. fertility parameters, i.e., sperm count, morphology, motility volume. Samples were prepared using a protein precipitation procedure analyzed liquid chromatography (LC) high-resolution mass spectrometry (HRMS). Non-targeted analysis (NTA) revealed eighteen chemicals not previously reported human studies, with 3-hydroxyoctanedioic acid, cosmetic additive, emerging as plausible candidate found to be at higher levels cases controls (p < 0.01) associated adverse morphology. This study aims first its kind utilize NTA understand association contaminants concern (CECs) along full profile find trends separating poor normal health parameters each other chemically. Our results suggest collective effects many CECs could adversely quality.
Язык: Английский
Процитировано
1
E3S Web of Conferences, Год журнала: 2023, Номер 431, С. 01010 - 01010
Опубликована: Янв. 1, 2023
In recent years the male gametes of plants are used for biotesting in ecotoxicology. High proportion sterile pollen is indicator environmental pollution and presence mutagens, which cause genetic disturbances. The viability Gorodkov’s rowan ( Sorbus gorodkovii Pojark) Scots pine Pinus sylvestris L.) vicinity environmentally hazard enterprises Arctic cities Murmansk region have been studied. following parameters were considered: number fertile their percentage ratio, sterility index, palynotoxic effect pollution. content abortive S. (55–65%), index (2.1–2.4) (38.2–50%) indicates mutagenicity genotoxicity emissions thermal power plants, that leads to formation gametes. level P. (42.5–50.7%), (1.4–1.7) (19.1–29.8%) indicates, mining processing plant "Apatit" containes mutagenic chemicals a genotoxic on gametophyte. can be bioindication environment as impact gametopathogenic factors.
Язык: Английский
Процитировано
2
E3S Web of Conferences, Год журнала: 2024, Номер 510, С. 03038 - 03038
Опубликована: Янв. 1, 2024
The results of influence industrial pollution on vegetative growth and pollen fertility Sorbus gorodkovii (Gorodkov,s rowan) in the impact area Pechenganickel plant (city Zapolyarny), are presented. Five experimental sites with S. were laid vicinity processing plant. Leaf measurements (leaf length total 2 middle leaflets a compound leaf) carried out every 7 days June July. Samples inflorescences mature selected from each site. Studies by acetocarmine method. It was found that is resistant to chronical environment heavy metals. Leaves significantly inhibited only beginning their ontogenesis. Pollen city Zapolyarny, high. Obtained data confirms previous some authors Subarctic climate Kola Peninsula, trees rapidly adapted anthropogenic stress increases resistance
Язык: Английский
Процитировано
0
Animal Reproduction Science, Год журнала: 2024, Номер unknown, С. 107519 - 107519
Опубликована: Июнь 1, 2024
Язык: Английский
Процитировано
0