The efficacy of wastewater treatment plant on removal of perfluoroalkyl substances and their impacts on the coastal environment of False Bay, South Africa DOI Creative Commons
Cecilia Y. Ojemaye,

Adeola P. Abegunde,

Lesley Green

et al.

Environmental Science and Pollution Research, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 18, 2024

Abstract Per- and polyfluoroalkyl substances (PFASs), which have their origins in both industrial processes consumer products, can be detected at all treatment stages wastewater plants (WWTPs). Quantifying the emissions of PFAS from WWTPs into marine environment is crucial because potential impacts on receiving aquatic ecosystems. In this study, levels five were measured influent effluent sewage water samples obtained a municipal WWTP, discharges flow False Bay, Indian Ocean coast Cape Town, South Africa. Additionally, seawater, sediment, biota eight sites along Bay also analysed. Results showed high prevalence different environmental matrices. Perfluorononanoic acid was most dominant these matrices with maximum concentration wastewater, 10.50 ng/L; 18.76 239.65 ng/g dry weight (dw); invertebrates, 0.72–2.45 µg/g dw; seaweed, 0.36–2.01 dw. The study used chemical fingerprint PFASs WWTP effluents to track dispersion across large, previously pristine examined how each accumulated organisms. demonstrates that primary secondary cannot fully remove such compounds. There thus need improve quality before its release promote continuous monitoring focusing sources PFAS, including transformation fate ecological risks, particularly areas WWTP.

Language: Английский

The adverse role of endocrine disrupting chemicals in the reproductive system DOI Creative Commons

Jing Pan,

Pengfei Liu,

Xiao Yu

et al.

Frontiers in Endocrinology, Journal Year: 2024, Volume and Issue: 14

Published: Jan. 17, 2024

Reproductive system diseases pose prominent threats to human physical and mental well-being. Besides being influenced by genetic material regulation changes in lifestyle, the occurrence of these is closely connected exposure harmful substances environment. Endocrine disrupting chemicals (EDCs), characterized hormone-like effects, have a wide range influences on reproductive system. EDCs are ubiquitous natural environment present industrial everyday products. Currently, thousands been reported exhibit endocrine this number likely increase as testing for potential has not consistently required, obtaining data limited, partly due long latency many diseases. The ability avoid EDCs, especially those artificially synthesized origin, increasingly challenging. While can be divided into persistent non-persistent depending their degree degradation, recent uptick research studies area, we chosen focus pertaining detrimental effects health several that widely encountered daily life over past six years, specifically bisphenol A (BPA), phthalates (PAEs), polychlorinated biphenyls (PCBs), parabens, pesticides, heavy metals, so on. By focusing impact hypothalamic-pituitary-gonadal (HPG) axis, which leads development diseases, review aims provide new insights molecular mechanisms EDCs’ damage encourage further in-depth clarify potentially EDC through various other mechanisms. Ultimately, it offers scientific basis enhance risk management, an endeavor significant societal importance safeguarding health.

Language: Английский

Citations

42
Suspect screening and quantitative analysis of 165 contaminants of emerging concern in water, sediments, and biota using LC-MS/MS: Ecotoxicological and human health risk assessment DOI
Alice Cristina da Silva, Luan Valdemiro Alves de Oliveira, Luan Amaral Alexandre

et al.

The Science of The Total Environment, Journal Year: 2025, Volume and Issue: 963, P. 178434 - 178434

Published: Jan. 17, 2025

Language: Английский

Citations

2
The impact of triadimenol on male fertility: An in vitro study and molecular docking examination DOI

Merve Arici,

Bilgehan Ayşenur,

Dincel Efe Dogukan

et al.

Reproductive Toxicology, Journal Year: 2025, Volume and Issue: 132, P. 108861 - 108861

Published: Feb. 13, 2025

Language: Английский

Citations

1
Chromatographic Methods for the Determination of Organic Pollution in Urban Water: A Current Mini Review DOI
Paulina Gątarek, Angelina Rosiak, Joanna Kałużna‐Czaplińska

et al.

Critical Reviews in Analytical Chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 18

Published: March 7, 2024

The number of pollutants and chemicals with the potential to reach environment is still largely unknown, which poses great challenges for researchers in various fields science, environmental scientists, analytical chemists. Chromatographic techniques, both gas chromatography (GC) liquid (LC) coupled different types detection, are now invaluable tools identification a wide range chemical compounds contaminants water. This review devoted chromatographic techniques GC-MS, GC-Orbitrap-MS, GC-MS/MS, GC-HRMS, GC × GC-TOFMS, GC-ECD, LC-MS/MS, HPLC-UV, HPLC-PDA, UPLC-QTOFMS, used determinate emerging organic aquatic media, mainly urban water, published scientific literature over past several years. article also focuses on sample preparation methods analysis aqueous samples. Most research minimizing steps, reducing amount solvents used, speed analysis, ability apply it analytes sample. extremely important application sensitive selective monitor status water quality assess its impact human health.

Language: Английский

Citations

6
Addressing Contaminants of Emerging Concern in Aquaculture: A Vacuum Membrane Distillation Approach DOI Creative Commons
Claudio Marcos Eugênio Malaghini, Jussara Garcez, Rodrigo Barcellos Hoff

et al.

Membranes, Journal Year: 2025, Volume and Issue: 15(5), P. 127 - 127

Published: April 24, 2025

The presence of contaminants emerging concern (CECs) in agricultural and fisheries water has raised significant environmental health concerns. Vacuum membrane distillation (VMD) shown promise as an effective method for removing non-volatile contaminants, such CECs, from water. This study presents a novel application bench-scale VMD unit to treat Lagoa da Conceição, Florianópolis, Brazil, using microporous membranes (0.22 µm) under the following optimized conditions: 75 °C, flow rate 24 L·h−1, vacuum pressure −640 mmHg. system demonstrated remarkable performance several key antimicrobials, including sulfamethoxazole, ciprofloxacin, azithromycin, clindamycin (500 μg·L−1), with rejection rates 99.1%, 98%, 99.9%, 99%, respectively, average flux 7.08 L·m−2·h−1. Additionally, achieved substantial 99.98% salt rejection. Ecotoxicity tests revealed low toxicity azithromycin but high clindamycin, while human risk assessment indicated moderate-to-high risks ciprofloxacin clindamycin. findings highlight potential sustainable technology removal CECs biocompounds, enhancing safety reducing hazards. offers promising solution addressing contamination on broader scale.

Language: Английский

Citations

0
Spatial and Household Determinants of Pesticide Exposure Among Girls in a Rural Agricultural Region of Costa Rica DOI

Mecca E. Howe,

Yaw Edu Essandoh,

Kevin Romanak

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0
Human sperm as an in vitro toxicity model: a versatile tool for assessing the risk of environmental contaminants DOI Creative Commons

Shannen Keyser,

Daniel Marcu,

Morgan T D Davidse

et al.

Archives of Toxicology, Journal Year: 2025, Volume and Issue: unknown

Published: May 3, 2025

Abstract Contaminants of emerging concern (CECs) pose a significant threat to human and ecosystem health due their persistence, bioaccumulation in higher trophic levels, potential toxicity. While vivo models are commonly used for toxicity screening, developing alternative vitro techniques rapid environmental risk assessment is essential. Spermatozoa, with compartmentalized structure, measurable characteristics sensitivity changes, offer as an model screening. We evaluated the impact selected CECs, including pharmaceuticals pesticides, on sperm function highly motile subpopulations from donor semen. Standardised protocols were applied assess various functional parameters after 1–4 h exposure either individual or mixture chemicals. Our findings revealed that total motility insufficient detect subtle toxic effect. More responsive measures, such kinematics, induced hyperactivation, viability, mitochondrial membrane (MMP) presence reactive oxygen species (ROS) should be assessed elucidate effect environment function. Most chemicals exerted dose–response parameters, concentrations resulting most negative effects. The inherent spermatozoa oxidative stress, damage energy metabolism, makes them robust assessing These features highlight utility cellular evaluating CECs advancing methodologies.

Language: Английский

Citations

0
Photolytic Transformation of Trace Organic Compounds: Roles of Direct Photolysis and Indirect Photolysis by Singlet Oxygen DOI
Doorae Lee, Ibrahim Alyami, Hercílio E. Zimila

et al.

Water Research, Journal Year: 2025, Volume and Issue: unknown, P. 123799 - 123799

Published: May 1, 2025

Language: Английский

Citations

0
Non-Targeted Analysis of Environmental Contaminants and Their Associations with Semen Health Factors in Men from New York City DOI Creative Commons
Trevor A. Johnson,

Sarah Adelman,

Bobby B. Najari

et al.

Environment & Health, Journal Year: 2024, Volume and Issue: 3(2), P. 164 - 176

Published: Nov. 3, 2024

Characterizing the chemical composition of semen can provide valuable insights into exposome and environmental factors that directly affect seminal overall health. In this study, we compared molecular profiles 45 donated samples from general population New York City participants examined correlation between in fertility parameters, i.e., sperm concentration, motility, morphology, volume. Samples were prepared using a protein precipitation procedure analyzed liquid chromatography (LC) coupled to high-resolution mass spectrometry (HRMS). Non-targeted analysis (NTA) revealed 18 chemicals not previously reported human studies, with 3-hydroxyoctanedioic acid, cosmetic additive, emerging as plausible candidate found be at higher levels cases vs controls (p < 0.01) associated adverse motility morphology. Four level 1 identified compounds have associations health parameters; dibutyl phthalate 2-aminophenol negatively impacted 4-nitrophenol was low while palmitic acid both morphology This study aims utilize NTA understand association contaminants concern (CECs) along full profile find trends separating poor normal parameters each other chemically. Our results suggest collective effects many CECs could adversely quality.

Language: Английский

Citations

2
Non-Targeted Assessment of Environmental Contaminants and their Correlations with Semen Health Factors in New York City DOI Creative Commons
Trevor A. Johnson,

Sarah Adelman,

Bobby B. Najari

et al.

Published: Sept. 2, 2024

Characterizing chemical composition of semen can provide valuable insights into the exposome and environmental factors that directly affect seminal overall health. In this study, we compared molecular profiles 45 donated samples from general population New York City participants examined correlation between in vs. fertility parameters, i.e., sperm count, morphology, motility volume. Samples were prepared using a protein precipitation procedure analyzed liquid chromatography (LC) high-resolution mass spectrometry (HRMS). Non-targeted analysis (NTA) revealed eighteen chemicals not previously reported human studies, with 3-hydroxyoctanedioic acid, cosmetic additive, emerging as plausible candidate found to be at higher levels cases controls (p < 0.01) associated adverse morphology. This study aims first its kind utilize NTA understand association contaminants concern (CECs) along full profile find trends separating poor normal health parameters each other chemically. Our results suggest collective effects many CECs could adversely quality.

Language: Английский

Citations

1