Biogenic synthesis and characterization of antimicrobial, antioxidant, and antihemolytic zinc oxide nanoparticles from Desertifilum sp. TN-15 cell extract DOI Creative Commons

Taswar Nadeem,

Muhammad Kaleem, Lubna Anjum Minhas

и другие.

Discover Nano, Год журнала: 2024, Номер 19(1)

Опубликована: Окт. 2, 2024

Abstract Cyanobacteria, being a prominent category of phototrophic organism, exhibit substantial potential as valuable source bioactive compounds and phytonutrients, including liposomes, amino derivatives, proteins, carotenoids. In this investigation, polyphasic approach was employed to isolate characterize newly discovered cyanobacterial strain from rice field in the Garh Moor district Jhang. Desertifilum sp. TN-15, unique less explored strain, holds significant promise novel candidate for synthesis nanoparticles. This noticeable research gap underscores novelty untapped TN-15 nanomedicine. The characterization biogenically synthesized ZnO–NPs involved application diverse analytical techniques. Ultraviolet–visible spectroscopy revealed surface plasmon resonance peak at 298 nm. Fourier transform infrared spectral analysis utilized confirm involvement biomolecules biogenic stability. Scanning electron microscopy probe morphology unveiling their size 94.80 nm star-shaped. Furthermore, X-ray diffraction substantiated crystalline nature ZnO–NPs, with measuring 46 To assess physical stability zeta dynamic light scattering measurements were conducted, yielding values + 31.6 mV, nm, respectively, indicative favorable antibacterial capabilities are attributed its abundance components, Through zinc oxide nanoparticles (ZnO–NPs) we have effectively used these chemicals generate that noteworthy activity against Staphylococcus aureus (MIC: 30.05 ± 0.003 µg/ml). Additionally, displayed potent antifungal antioxidant properties, well antihemolytic effects on red blood cells (IC 50 : 4.8 Cytotoxicity assessment using brine shrimps an IC value 3.1 µg/ml. multifaceted actions underscore applications pharmacological therapeutic fields. study proposes method production utilizing recently identified highlighting growing significance biological systems environmentally friendly fabrication metallic nanomaterials.

Язык: Английский

Catalyzing innovation: Exploring iron oxide nanoparticles - Origins, advancements, and future application horizons DOI
Pankaj Kumar, Nikesh Thakur, Kuldeep Kumar

и другие.

Coordination Chemistry Reviews, Год журнала: 2024, Номер 507, С. 215750 - 215750

Опубликована: Фев. 29, 2024

Язык: Английский

Процитировано

42

Green synthesis of iron oxide nanoparticles for mitigation of chromium stress and anti-oxidative potential in Triticum aestivum DOI Creative Commons

Saleha Zafar,

Atikah Farooq,

Sana Batool

и другие.

Hybrid Advances, Год журнала: 2024, Номер 5, С. 100156 - 100156

Опубликована: Фев. 21, 2024

Язык: Английский

Процитировано

18

Iron Oxide Nanoparticles: Green Synthesis and Their Antimicrobial Activity DOI Creative Commons
Johana Zúñiga-Miranda, Julio Guerra, Alexander Mueller

и другие.

Nanomaterials, Год журнала: 2023, Номер 13(22), С. 2919 - 2919

Опубликована: Ноя. 8, 2023

The rise of antimicrobial resistance caused by inappropriate use these agents in various settings has become a global health threat. Nanotechnology offers the potential for synthesis nanoparticles (NPs) with activity, such as iron oxide (IONPs). IONPs is promising way to overcome or pathogenicity because their ability interact several biological molecules and inhibit microbial growth. In this review, we outline pivotal findings over past decade concerning methods green using bacteria, fungi, plants, organic waste. Subsequently, delve into primary challenges encountered utilizing diverse organisms materials. Furthermore, compile most common employed characterization IONPs. To conclude, highlight applications antibacterial, antifungal, antiparasitic, antiviral agents.

Язык: Английский

Процитировано

31

Breaking Barriers in Eco-Friendly Synthesis of Plant-Mediated Metal/Metal Oxide/Bimetallic Nanoparticles: Antibacterial, Anticancer, Mechanism Elucidation, and Versatile Utilizations DOI Open Access
Swati Dubey, Tarun Virmani, ShivKumar Yadav

и другие.

Journal of Nanomaterials, Год журнала: 2024, Номер 2024, С. 1 - 48

Опубликована: Апрель 12, 2024

Nanotechnology has emerged as a promising field in pharmaceutical research, involving producing unique nanoscale materials with sizes up to 100 nm via physiochemical and biological approaches. Nowadays more emphasis been given eco-friendly techniques for developing nanomaterials enhance their applications minimize health environmental risks. With the help of green nanotechnology, wide range metal, metal oxide, bimetallic nanoparticles distinct chemical compositions, sizes, morphologies have manufactured which are safe, economical, environment friendly. Due biocompatibility vast potential biomedical (antibacterial, anticancer, antiviral, analgesic, anticoagulant, biofilm inhibitory activity) other fields such (nanofertilizers, fermentative, food, bioethanol production, construction field), garnered significant interest worldwide. The precursors combined natural extracts plants, algae, fungi, bacteria get potent novel Ag, Au, Co, Cu, Fe, Zr, Zn, Ni, Pt, Mg, Ti, Pd, Cd, Bi2O3, CeO2, Co3O4, CoFe2O4, CuO, Fe2O3, MgO, NiO, TiO2, ZnO, ZrO2, Ag-Au, Ag-Cr, Ag-Cu, Ag-Zn, Ag-CeO2, Ag-CuO, Ag-SeO2, Ag-TiO2, Ag-ZnO, Cu-Ag, Cu-Mg, Cu-Ni, Pd-Pt, Pt-Ag, ZnO-CuO, ZnO-SeO, ZnO-Se, Se-Zr, Co-Bi2O3. These plant-mediated possess excellent antibacterial anticancer activity when tested against several microorganisms cancer cell lines. Plants contain essential phytoconstituents (polyphenols, flavonoids, terpenoids, glycosides, alkaloids, etc.) compared sources (bacteria, algae) higher concentration that play vital role development because these plant-phytoconstituents act reducing, stabilizing, capping agent helps nanoparticles. After concluding all findings, this review designed first time way it imparts satisfactory knowledge about together, along mechanisms. Additionally, provides information characterization (UV–vis, FT-IR, DLS, XRD, SEM, TEM, BET, AFM) employed nanoparticles, applications, industries. Hence, various types versatile application diverse is not covered pieces literature.

Язык: Английский

Процитировано

13

Algae-derived bioactive compounds as potential pharmaceuticals for cancer therapy: A comprehensive review DOI Creative Commons
Lubna Anjum Minhas, Muhammad Kaleem, Hafiz Muhammad Umer Farooqi

и другие.

Algal Research, Год журнала: 2024, Номер 78, С. 103396 - 103396

Опубликована: Янв. 18, 2024

Cancer is considered a pandemic, costing precious lives throughout the globe. Besides its deadly outcomes, survival rate after cancer therapies meager. Anti-cancer drug resistance and cytotoxicity are leading causes of poor prognosis anticancer treatments. Though advancements in genetic engineering, nanotechnology, bioinformatics revolutionized discovery development, importance natural compounds for development indispensable. Algae reservoirs distinctive chemical entities offer promising line research. Chemotherapy has been beneficial up to now, but it also comes with quite undesirable side effects. algae-derived products an area that revolutionizing itself as these less poisonous, quicker, cheaper, safer, more environmentally friendly than traditional treatment approaches. Complementary alternative extracted from marine or freshwater flora, particularly prokaryotic eukaryotic algae, have studied their pharmaceutical potential. However, application nutraceuticals still infancy. Algae, autotrophic organism, most untapped richest source compounds. Through this comprehensive review, efforts made draw attention recent significant achievements algae-based therapeutics target nuclear cellular components. Additionally, challenges solutions discussed detail.

Язык: Английский

Процитировано

10

Biogenic synthesis of iron oxide nanoparticles and experimental modeling studies on the removal of heavy metals from wastewater DOI Creative Commons
Muhammad Kaleem, Lubna Anjum Minhas, Muhammad Zaffar Hashmi

и другие.

Journal of Saudi Chemical Society, Год журнала: 2023, Номер 28(1), С. 101777 - 101777

Опубликована: Дек. 7, 2023

Water pollution is a major global challenge due to the fast expansion of industrial activities and increasing human population. Certain heavy metals can be exceedingly hazardous contribute significantly water contamination. In this study, iron oxide nanoparticles (IONPs) were synthesized using cyanobacteria extract remove (Cd Pb) from wastewater. To characterize IONPs, several analytical techniques employed such as Ultraviolet-visible spectroscopy revealed an SPR (surface plasmon resonance) peak at 348 nm, FTIR (Fourier transform infrared) spectral analysis show OH, C-H S=O functional groups which confirmed biomolecules responsible for biogenic synthesis stability. The surface morphology IONPs was investigated (SEM) scanning electron reveled their nearly spherical or cubic shape. Additionally, XRD (X-ray diffraction) crystallinity with crystalline size measuring 18.21 nm. Effects contact time, pH, initial metal ions concentrations, dosage studied on adsorption Cd Pb ions. Different kinetics isotherm models applied experimental data. Pseudo second-order kinetic Langmuir well fitted onto IONPs. Higher correlation coefficients (R2) values (R2: 0.990 adsorption) 0.998 0.999 adsorption, respectively) found, indicated favorable interaction between adsorbent. calculated maximal capacities 105.932 118.764 mg/g Pb, respectively. Recyclability conducted after five adsorption/desorption cycles, retained efficiency negligible decline. After removal up 80.41 88.35 % Results study indicate that cyanobacteria-mediated efficient adsorbent contaminated aqueous solution.

Язык: Английский

Процитировано

20

Sustainable Synthesis of Cobalt Oxide Nanoparticles (Co3O4-NPs) Using Extract of Nodosilinea nodulosa: Characterization and Potential Biological Applications DOI

Faiqa Aslam,

Lubna Anjum Minhas, Muhammad Kaleem

и другие.

BioNanoScience, Год журнала: 2024, Номер 14(5), С. 4764 - 4778

Опубликована: Июль 30, 2024

Язык: Английский

Процитировано

6

Synthesis of Silver Oxide Nanoparticles: A Novel Approach for Antimicrobial Properties and Biomedical Performance, Featuring Nodularia haraviana from the Cholistan Desert DOI Creative Commons
Lubna Anjum Minhas, Muhammad Kaleem,

Amber Jabeen

и другие.

Microorganisms, Год журнала: 2023, Номер 11(10), С. 2544 - 2544

Опубликована: Окт. 12, 2023

Nanoparticles have emerged as a prominent area of research in recent times, and silver nanoparticles (AgNPs) synthesized via phyco-technology gained significant attention due to their potential therapeutic applications. Nodularia haraviana, unique lesser-explored cyanobacterial strain, holds substantial promise novel candidate for synthesizing nanoparticles. This noticeable gap underscores the novelty untapped haraviana applied nanotechnology. A range analytical techniques, including UV-vis spectral analysis, dynamic light scattering spectroscopy, scanning electron microscopy, Fourier transform infrared X-ray powder diffraction, were used investigate characterize AgNPs. Successful synthesis AgNPs was confirmed through UV-visible which showed surface plasmon resonance peak at 428 nm. The crystalline size 24.1 Dynamic analysis revealed that oxide had 179.3 nm diameters negative charge −18 mV. Comprehensive vitro pharmacogenetic properties potential. antimicrobial evaluated by determining minimum inhibitory concentration against various microbial strains. Dose-dependent cytotoxicity assays performed on Leishmanial promastigotes (IC50: 18.71 μgmL−1), amastigotes 38.6 brine shrimps 134.1 μg mL−1) using concentrations findings this study antioxidant results (DPPH: 57.5%, TRP: 55.4%, TAC: 61%) enzyme inhibition protein kinase (ZOI: 17.11 mm) alpha-amylase (25.3%). Furthermore, biocompatibility tests macrophages >395 human RBCs 2124 mL−1). phyco-synthesized less toxic could be multiple biological applications, drug design pharmaceutical biomedical industries. offers valuable insights paves way further advancements research.

Язык: Английский

Процитировано

15

Green synthesis of iron oxide nanoparticles using Lyptolyngbya foveolarum and Azospirillum brasilense for wastewater treatment DOI Creative Commons
Mostafa M. El‐Sheekh, Mohamed T. Shaaban, A Goda

и другие.

International Journal of Environmental Science and Technology, Год журнала: 2025, Номер unknown

Опубликована: Янв. 4, 2025

Abstract Nanotechnology applications in the treatment of wastewater are becoming a growing trend. These days, eco-friendly production nanoparticles is increasingly vital. Among different multiple studies have been conducted on iron because their strong reducing power and high reactivity. Two types (magnetite Fe 3 O 4 hematite 2 ) were synthesized using Lyptolyngbya foveolarum extract Azospirillum brasilense supernatant. Characterization via UV analysis, X-ray diffraction (XRD) pattern, transmission electron microscopy, Fourier transform infrared spectrum, zeta potential, (dynamic light scattering) DLS validated successfully oxide including magnetite plus hematite. The current investigation aims to compare efficacy each type nanoparticle alone at concentrations eliminate ammonia, nitrate, phosphate, COD, BOD from wastewater. Synergism between two reveals removal efficiency equals 87.68%, 91.87%, 71.9%, 81.75%, 82% with BOD, respectively.

Язык: Английский

Процитировано

0

Biosynthesis and characterization of iron oxide nanoparticles fabricated using cell-free supernatant of Pseudomonas fluorescens for antibacterial, antifungal, antioxidant, and photocatalytic applications DOI Creative Commons
Sanaz Ashrafi-Saiedlou, MirHassan Rasouli-Sadaghiani, Mohammad Reza Fattahi

и другие.

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Янв. 6, 2025

This study investigates the biosynthesis of iron oxide nanoparticles (Fe2O3NPs) using cell-free supernatant Pseudomonas fluorescens. The synthesized Fe2O3NPs were characterized through UV–VIS, XRD, FTIR, FESEM, EDX, TEM, BET, and VSM analyses. XRD results confirmed that successfully EDX analysis indicated accounted for 89.5% sample composition. Imaging via SEM TEM revealed average diameters 20.43 ± 5.38 nm 24.32 5.03 nm, respectively. antimicrobial effects assessed against four bacterial strains fungal species. Inhibition zones 8.35 0.103 mm 8.31 0.128 observed syringae Staphylococcus aureus at a concentration 400 μg mL−1 Fe2O3NPs. Antifungal efficacy showed growth rate reductions 90.4% Aspergillus niger, 71.1% Monilinia fructigena, 68.8% Botrytis cinerea, 84.2% Penicillium expansum, compared to controls. demonstrated photocatalytic degradation efficiencies 89.93%, 84.81%, 79.71% methyl violet, orange, methylene blue, Also exhibited significant DPPH free radical scavenger activity with an IC50 value 8.45 0.59 mL−1. study's findings underscored potential in addressing environmental pollution combating pathogenic microorganisms.

Язык: Английский

Процитировано

0