Rising Concern About the Carcinogenetic Role of Micro-Nanoplastics DOI Open Access
Lorenzo Ruggieri, Ottavia Amato, Cristina Marrazzo

и другие.

International Journal of Molecular Sciences, Год журнала: 2024, Номер 26(1), С. 215 - 215

Опубликована: Дек. 30, 2024

In recent years, awareness regarding micro-nanoplastics’ (MNPs) potential effects on human health has progressively increased. Despite a large body of evidence the origin and distribution MNPs in environment, their impact remains to be determined. this context, there is major need address carcinogenic risks, since could hypothetically mediate direct indirect effects, latter mediated by particle-linked chemical carcinogens. Currently, field scarce heterogeneous, but reported increased incidence malignant tumors among younger populations, together with ubiquitous environmental abundance MNPs, are rising global concern possible role development progression cancer. review, we provide an overview currently available eco-toxicology, as well methods for identification characterization MNP particulates health-associated focus addition, suggest routes future research order unravel carcinogenetic exposure understand prognostic preventive implications intratumoral MNPs.

Язык: Английский

Microplastics in aquatic ecosystems: Detection, source tracing, and sustainable management strategies DOI Creative Commons
Baihui Wu,

Haiyang Yu,

Pengyu Lei

и другие.

Ecotoxicology and Environmental Safety, Год журнала: 2025, Номер 291, С. 117883 - 117883

Опубликована: Фев. 1, 2025

Microplastics (MPs) are emerging contaminants characterized by persistence, cross-media transport, and complex pollutant interactions, posing serious ecotoxicological risks to ecosystems human health. Effective MPs management requires multi-faced, long-term, strategies involving targeted sampling, quantitative detection, comprehensive risk assessments, all of which entail significant resource investment. Despite advancements in remediation technologies, a holistic governance framework integrating these innovations remains underdeveloped. This review synthesizes current knowledge on MPs, elaborating their diverse morphologies, degradation pathways, role as vectors for toxic substances. State-of-the-art extraction techniques evaluated this article, including micropore adsorption using nanocomposites, alongside the incorporation advanced analytical tools such spectroscopic methods, electron microscopy, bioinformatics augment environmental forensics. also underscores necessity formulating robust global policies regulate pollution discusses potential biodegradation thermal sustainable solutions removal. By promoting an interdisciplinary approach, advocates coordinated response, science, policy frameworks, waste mitigate escalating impact well-being.

Язык: Английский

Процитировано

2

Microplastics in honey from Türkiye: Occurrence, characteristic, human exposure, and risk assessment DOI
Burhan Başaran, Zehra Özçi̇fçi̇, Esra Demir Kanbur

и другие.

Journal of Food Composition and Analysis, Год журнала: 2024, Номер 135, С. 106646 - 106646

Опубликована: Авг. 11, 2024

Язык: Английский

Процитировано

11

Ingested Polystyrene Micro-Nanoplastics Increase the Absorption of Co-Ingested Arsenic and Boscalid in an In Vitro Triculture Small Intestinal Epithelium Model DOI Creative Commons
Davood Kharaghani, Glen M. DeLoid, Trung Huu Bui

и другие.

Microplastics, Год журнала: 2025, Номер 4(1), С. 4 - 4

Опубликована: Янв. 7, 2025

Micro-nano plastics (MNPs) are emerging environmental and food contaminants that raising serious health concerns. Due to the polycontamination of web with pollutants (EPs), now MNPs, co-ingestion EPs MNPs is likely occur, potential synergistic effects such co-ingestions completely unstudied. In this study, we therefore sought determine two model EPs, arsenic boscalid, on uptake toxicity 25 1000 nm polystyrene (PS-25 PS-1000), vice versa, employing a triculture small intestinal epithelium combined simulated digestion. 24 h exposures, neither nor + caused significant toxicity. The presence PS-25 significantly increased (from 0.0 5.8%, p < 0.001) translocation 5.2 9.8%, 0.05) but had no effect boscalid or translocation, whereas PS-1000 either EP. both PS was also by rising from 10.6 19.5% (p 0.01) for 4.8 8.5% PS-1000. These findings highlight need further studies assess MNP-EP interactions possible adverse impacts.

Язык: Английский

Процитировано

1

Unveiling Hidden Threats: Introduction of a Routine Workflow for Label-Free and Non- destructive Detection of Microplastics in Human FFPE Tissue Sections DOI Open Access
Elisabeth S. Gruber,

Verena Karl,

Kristina Duswald

и другие.

medRxiv (Cold Spring Harbor Laboratory), Год журнала: 2025, Номер unknown

Опубликована: Янв. 10, 2025

ABSTRACT Microplastic (MP) pollution has emerged as a significant environmental and health concern. This study aimed at developing novel method for detecting MP particles in deparaffinized formalin-fixed paraffin-embedded (FFPE) routine tissue sections of human colon samples. By utilizing mid-infrared photothermal (MIP) microscopy, also known optical infrared (OPTIR) spectroscopy, we here to establish work-flow representing non-destructive spectroscopic approach distinct identification localization polymers FFPE by respecting standardized protocols well integrated into clinical routine. After OPTIR analysis, samples were processed H&E staining histopathological analysis defined regions interest. using succeeded localizing polyethylene (PE), polystyrene (PS), terephthalate (PET) MPs interest (21 PE particles, 1 PS particle, PET fiber) clearly identifying the embedded respective sections. Subsequent confirmed characteristic features inflammation spatially associated with polymers. We present first time diagnostic workflow that potential enhance our understanding accumulation organ slides allows exploration its implications health. The observed morphological proximity identified could possibly indicate link between exposure inflammation.

Язык: Английский

Процитировано

0

Microplastic production, distribution, and removal from the environment: a review DOI
Yu. V. Ioni,

Muhammad Farooq,

D. Roshka

и другие.

Russian Chemical Reviews, Год журнала: 2025, Номер 94(3), С. RCR5155 - RCR5155

Опубликована: Март 1, 2025

The presence of microplastics (MPs) in the environment is a highly relevant and aggravating environmental problem, which concern not only for specialists various fields but also everyone who cares about future Earth. ever-increasing production polymers expanding use plastic products enlarged MP concentrations Earth's ecosystem. need to control accumulation spread MPs caused by current crisis where no microplastic-free areas have remained on number studies dealing with existing potential threat living organisms from consumption increasing every year. aim this review systematize available information occurrence briefly describe main types polymer materials acting as sources mechanisms formation transport environment. hazardous behaviour analyzed considering their impact physiology aquatic soil organisms. Special emphasis demonstrating adverse effect emissions 3D printing materials. An overview methods capture given facilitate analysis development more reliable removal disposal. As result review, we assess long-term human health consequences exposure. Understanding formation, lifecycle environment, ways interaction will controlling design implementation effective techniques remediation prevent ecological consequences. <br>The bibliography includes 244 references.

Язык: Английский

Процитировано

0

Indoor Airborne Microplastics: Human Health Importance and Effects of Air Filtration and Turbulence DOI Creative Commons
Christine C. Gaylarde, José Antônio Baptista Neto, Estefan Monteiro da Fonseca

и другие.

Microplastics, Год журнала: 2024, Номер 3(4), С. 653 - 670

Опубликована: Ноя. 5, 2024

Microplastics (MPs) are omnipresent particles that receive special attention because of their persistent nature and potential impact on human disease the environment. Most MPs generated by degradation larger plastic items such as clothing, car tires, discarded materials. In indoor environments, where beings spend most time, aerial MP levels higher, majority fibers produced from textiles. Airborne indoors a greater danger to humans than ingested in food drink. Fragments small enough remain substantially suspended air column, airborne microparticles measured PM10 PM2.5, become available for assimilation through respiration, potentially producing various health problems. Larger act ingestion skin contact. can carry microorganisms micropollutants adsorbed surfaces, facilitating uptake survival within body. Indoor thus represent emerging pollutants fast-growing concern especially important invaders respiratory system, reaching alveoli lungs finally entering circulatory system other tissues. Since this direct exposure contamination via is so important, we discuss article ways which concentration dispersal be affected turbulence induced anthropogenic objects conditioners, filters, purifiers. Much evidence equivocal further research necessary.

Язык: Английский

Процитировано

1

Micro-Nanoparticle Characterization: Establishing Underpinnings for Proper Identification and Nanotechnology-Enabled Remediation DOI Open Access

Wesley Allen Williams,

Shyam Aravamudhan

Polymers, Год журнала: 2024, Номер 16(19), С. 2837 - 2837

Опубликована: Окт. 8, 2024

Microplastics (MPLs) and nanoplastics (NPLs) are smaller particles derived from larger plastic material, polymerization, or refuse. In context to environmental health, they separated into the industrially-created “primary” category degradation derivative “secondary” where exhibit different physiochemical characteristics that attenuate their toxicities. However, some particle types more well documented in terms of fate environment potential toxicological effects (secondary) versus industrial fabrication chemical characterization (primary). Fourier Transform Infrared Spectroscopy (FTIR/µ-FTIR), Raman/µ-Raman, Proton Nuclear Magnetic Resonance (H-NMR), Curie Point-Gas Chromatography-Mass Spectrometry (CP-gc-MS), Induced Coupled Plasma-Mass (ICP-MS), Nanoparticle Tracking Analysis (NTA), Field Flow Fractionation-Multiple Angle Light Scattering (FFF-MALS), Differential Scanning Calorimetry (DSC), Thermogravimetry (TGA), Mobility Particle [Sizing] (DMPS), Electron Microscopy (SEM), Transmission (TEM), X-ray Microspectroscopy (STXM) reviewed as part a suite methods for ascertainment distinguishment. addition, Optical-Photothermal (O-PTIR), Z-Stack Confocal Microscopy, Mueller Matrix Polarimetry, Digital Holography (DH) touched upon cutting-edge modes characterization. Organizations, like water treatment waste management industry, those groups bring awareness this issue, which direct contact with hydrosphere, can utilize these techniques order sense remediate polymer pollution. The primary goal review paper is highlight extent pollution introduce its effect on biodiversity planet while underscoring current field research. secondary involves illustrating theoretical avenues future research needs address optimize MPL/NPL remediation, utilizing nanotechnology, before sleeping giant problem awakens.

Язык: Английский

Процитировано

0

The Effects of Microplastics on Musculoskeletal Disorder; A Narrative Review DOI Creative Commons

Hiroyori Fusagawa,

Alex Youn,

Elyse Wilkerson

и другие.

Current Reviews in Musculoskeletal Medicine, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 22, 2024

Abstract Purpose of Review The physical health impacts microplastics have received increasing attention in recent years. However, limited data impedes a full understanding the internal exposure to microplastics, especially concerning musculoskeletal system. purpose this review is summarize literature regarding effects on Recent Findings Microplastics been shown cause abnormal endochondral ossification and disrupt normal function pre-osteoblasts, osteocyte-like cells, pre-osteoclasts through gene mutations, endoplasmic reticulum stress induction, reduced autophagosome formation bone growth areas. Although there are few reports their muscle, it has noted that inhibit energy lipid metabolism, decrease type I muscle fiber density, impair angiogenesis, atrophy, increase deposition. Summary Only studies interfere with growth-related cells reduce mass quality. This underscores need for further research into other parts system using human tissues at disease level.

Язык: Английский

Процитировано

0

Rising Concern About the Carcinogenetic Role of Micro-Nanoplastics DOI Open Access
Lorenzo Ruggieri, Ottavia Amato, Cristina Marrazzo

и другие.

International Journal of Molecular Sciences, Год журнала: 2024, Номер 26(1), С. 215 - 215

Опубликована: Дек. 30, 2024

In recent years, awareness regarding micro-nanoplastics’ (MNPs) potential effects on human health has progressively increased. Despite a large body of evidence the origin and distribution MNPs in environment, their impact remains to be determined. this context, there is major need address carcinogenic risks, since could hypothetically mediate direct indirect effects, latter mediated by particle-linked chemical carcinogens. Currently, field scarce heterogeneous, but reported increased incidence malignant tumors among younger populations, together with ubiquitous environmental abundance MNPs, are rising global concern possible role development progression cancer. review, we provide an overview currently available eco-toxicology, as well methods for identification characterization MNP particulates health-associated focus addition, suggest routes future research order unravel carcinogenetic exposure understand prognostic preventive implications intratumoral MNPs.

Язык: Английский

Процитировано

0