Опубликована: Авг. 13, 2024
Язык: Английский
Matter, Год журнала: 2025, Номер 8(3), С. 101942 - 101942
Опубликована: Янв. 13, 2025
Язык: Английский
Процитировано
2
Advanced Science, Год журнала: 2025, Номер unknown
Опубликована: Янв. 23, 2025
Reactive oxygen species (ROS) play a dual role in wound healing. They act as crucial signaling molecules and antimicrobial agents when present at moderate levels. However, excessive levels of ROS can hinder the healing process for individuals with diabetes. As result, targeting to maintain redox balance has become promising strategy improving recovery. Currently, no biomaterials have been reported simultaneously up-regulate down-regulate achieve broad-spectrum antibacterial antioxidant properties. Inspired by site-dependent effect nanomaterials, micron-sized ferroferric oxide (Fe3O4)/MXene (FM) heterojunction is synthesized using hydrothermal method. The FM could scavenge extracellular activating catalase (CAT)-like superoxide dismutase (SOD)-like nanozyme activities. Meanwhile, release ferric ions ferrous defect engineering induce bacterial ferroptosis, up-regulating intercellular ROS, lipid peroxidation. For applications vivo, incorporated into tips gelatin methacryloyl (GelMA)-based microneedle (termed GFM microneedle) two-step casting technique. results showed that combined photothermal therapy improve S. aureus-infected skin regeneration diabetic rats. effectiveness safety are not less favorable than commercial dressing. This study provides proof-of-concept heterojunction-mediated regenerative medicine via ROS-targeting strategy.
Язык: Английский
Процитировано
0
Separation and Purification Technology, Год журнала: 2025, Номер unknown, С. 132678 - 132678
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0
Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 161994 - 161994
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0
ACS Applied Polymer Materials, Год журнала: 2025, Номер unknown
Опубликована: Апрель 10, 2025
Язык: Английский
Процитировано
0
Chemistry - An Asian Journal, Год журнала: 2025, Номер unknown
Опубликована: Апрель 22, 2025
Abstract Precise targeted delivery of antibiotics to infected sites is crucial for enhancing therapeutic efficacy and minimizing side effects. In this work, we present magnetic hydrogel‐based microrobots active antibiotic achieve bacterial elimination. These comprise a poly(acrylic acid‐co‐acrylamide) hydrogel microspheres encapsulating Fe 3 O 4 nanoparticle chains. The scaffold offers abundant spaces binding high‐capacity loading vancomycin via electrostatic interactions. embedded nanochains enable propulsion. Under rotating field ( H r t )), the can actively deliver their swarming motions, then eliminate bacteria (e.g., Staphylococcus aureus ) utilizing sustainable release on site. hold great promise as motile antibacterial platform treat infectious diseases.
Язык: Английский
Процитировано
0
Journal of Materials Chemistry B, Год журнала: 2024, Номер 12(41), С. 10550 - 10558
Опубликована: Янв. 1, 2024
Micro/nanorobots (MNRs) hold great promise for various applications due to their capability execute complex tasks in hard-to-reach micro/nano cavities. However, the developed magnetic MNRs, as marionettes of external fields, lack built-in intelligence self-targeting, while chemotactic MNRs suffer from limited self-targeting range. Here, we demonstrate magnetic-chemotactic ZnO/Fe-Ag Janus microrobots (JMRs) capable rapid, remote bacterial elimination. The JMRs utilize Fe engine coarse navigation a distance, allowing control swiftly guide them vicinity hidden/uncharted target that establishes local chemical gradient ([CO
Язык: Английский
Процитировано
1
Small, Год журнала: 2024, Номер unknown
Опубликована: Дек. 23, 2024
Abstract Micro/nanomotors (MNMs) are highly versatile small‐scale devices capable of converting external energy inputs into active motion. Among the various sources, light stands out due to its abundance and ability provide spatiotemporal control. However, effectiveness light‐driven motion in complex environments, such as biological tissues or turbid water, is often limited by scattering reduced penetration. To overcome these challenges, recent innovations have integrated light‐based actuation with other stimuli—such magnetic, acoustic, electrical fields—broadening functional range control MNMs. This review highlights cutting‐edge developments dual‐energy powered MNMs, emphasizing examples where paired secondary sources for enhanced propulsion task performance. Furthermore, insights offered fabrication techniques, biomedical applications, future directions hybrid while addressing remaining challenges this rapidly evolving field.
Язык: Английский
Процитировано
1
Journal of Drug Delivery Science and Technology, Год журнала: 2024, Номер unknown, С. 106410 - 106410
Опубликована: Ноя. 1, 2024
Язык: Английский
Процитировано
0
Deleted Journal, Год журнала: 2024, Номер 2(4)
Опубликована: Ноя. 1, 2024
Abstract Magnetic microparticles (MPs) and nanoparticles (NPs) have long been used as ideal miniaturized delivery detection platforms. Their use micro‐ nanorobots (MNRs) is also emerging in the recent years with help of more dedicated external magnetic field manipulations. In this review, we summarize research progress on nanoparticle (MNP)‐based MNRs. First, fabrication from either template‐assisted NP doping methods or directly synthesized MPs summarized. The driving torque sources for both types MNRs are analyzed, their propulsion control under low Reynolds number flows discussed by evaluating symmetry breaking mechanisms interparticle interactions. Subsequently, these scientific models, bioimaging agents, active delivery, treatment platforms (drug cell sterilization), biomedical diagnostics has reviewed. Finally, perspective MNPs‐based was outlined, including challenges future directions.
Язык: Английский
Процитировано
0